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Author: Richard D. Blake
Publisher: University Science Books
Published: 2005-03-23
Total Pages: 812
ISBN-13: 9781891389283
DOWNLOAD EBOOK →This new text examines thebiophysics and biochemistry of nucleic acids and proteins, carving outthe dynamic interface between chemistry and molecular biology, and providing adetailed picture of nucleic acids and proteins, their structures, biologicalproperties, and origins and evolution.
Author: M. Karin
Publisher: Springer Science & Business Media
Published: 2013-03-08
Total Pages: 313
ISBN-13: 1468468111
DOWNLOAD EBOOK →This book is the first volume in a new series Progress in Gene Expres sion. The control of gene expression is a central-most topic in molecular biology as it deals with the utilization and regulation of gene informa tion. As we see huge efforts mounting all over the developed world to understand the structure and organization of several complex eukaryotic genomes in the form of Gene Projects and Genome Centers, we have to remember that without understanding the basic mechanisms that gov ern the use of genetic information, much of this effort will not be very productive. Fortunately, however, research during the past seven years on the mechanisms that control gene expression in eukaryotes has been extremely successful in generating a wealth of information on the basic strategies of transcriptional control. (Although regulation of gene ex pression is exerted at many different levels, much of the emphasis in this series will be on transcriptional control. A future volume, however, will deal with other levels of regulation). The progress in understanding the control of eukaryotic transcription can only be appreciated by realizing that seven years ago we did not know the primary structure of a single sequence specific transcriptional activator, and those whose primary structures were available (e. g. , homeo domain proteins) were not yet recognized to function in this capacity.
Author: E. J. Murray
Publisher:
Published: 1991-04-22
Total Pages: 464
ISBN-13:
DOWNLOAD EBOOK →Biology is the study of living things. The classical approach might be described as holistic and descriptive, whereas the modern molecular - proach aims to be investigative, reductionist, and mechanistic . Genes contain all the information for the structure of all living things ; thus, the understanding of how genes are regulated is an important step toward understanding the nature of living things. The study of gene regulation has been made more tractable by the design of simple expe- mental models in which a single gene can be isolated from the milieu of the organism. The new science of molecular biology has introduced techniques that permit the design of such experimental models. In sequence, the genome of the organism is dissected in such a manner that specific genes may now be introduced into an appropriate cell line . Subsequent analysis of the proteins expressed from the genes under study results in the identification of the regulatory DNA sequences .
Author: Gerald M. Kolodny
Publisher: Springer
Published: 1980
Total Pages: 200
ISBN-13:
DOWNLOAD EBOOK →The cause of cancer and its many manifestations is at present unknown. Since many of its manifestations, including is control of cell division, appear to represent abnormal patterns of gene expression, studies of the regulation of gene expression nwill provide important insights in the understanding and treatment of cancer. This volume attempts to present some of the recent work on regulation of gene expression in eukaryotic cells.
Author: Tapan Gupta
Publisher: Springer
Published: 2017-10-25
Total Pages: 319
ISBN-13: 3319664050
DOWNLOAD EBOOK →All living things contain carbon in some form, as it is the primary component of macromolecules including proteins, lipids, nucleic acids (RNA and DNA), and carbohydrates. As a matter of fact, it is the backbone of all organic (chemistry) compounds forming different kinds of bonds. Carbon: The Black, the Gray and the Transparent is not a complete scientific history of the material, but a book that describes key discoveries about this old faithful element while encouraging broader perspectives and approaches to its research due to its vast applications. All allotropes of carbon are described in this book, along with their properties, uses, and methods of procurement or manufacturing. Black carbon is represented by coal, gray carbon is represented by graphite, and transparent carbon is represented by diamond.
Author: Wei-Shou Hu
Publisher: John Wiley & Sons
Published: 2017-09-11
Total Pages: 504
ISBN-13: 1119159032
DOWNLOAD EBOOK →This book is a short introduction to the engineering principles of harnessing the vast potential of microorganisms, and animal and plant cells in making biochemical products. It was written for scientists who have no background in engineering, and for engineers with minimal background in biology. The overall subject dealt with is process. But the coverage goes beyond the process of biomanufacturing in the bioreactor, and extends to the factory of cell’s biosynthetic machinery. Starting with an overview of biotechnology and organism, engineers are eased into biochemical reactions and life scientists are exposed to the technology of production using cells. Subsequent chapters allow engineers to be acquainted with biochemical pathways, while life scientist learn about stoichiometric and kinetic principles of reactions and cell growth. This leads to the coverage of reactors, oxygen transfer and scale up. Following three chapters on biomanufacturing of current and future importance, i.e. cell culture, stem cells and synthetic biology, the topic switches to product purification, first with a conceptual coverage of operations used in bioseparation, and then a more detailed analysis to provide a conceptual understanding of chromatography, the modern workhorse of bioseparation. Drawing on principles from engineering and life sciences, this book is for practitioners in biotechnology and bioengineering. The author has used the book for a course for advanced students in both engineering and life sciences. To this end, problems are provided at the end of each chapter.
Author: Samantha Fowler
Publisher:
Published: 2018-01-07
Total Pages: 618
ISBN-13: 9789888407453
DOWNLOAD EBOOK →Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.
Author: Thimmaiah Govindaraju
Publisher: CRC Press
Published: 2019-01-30
Total Pages: 293
ISBN-13: 0429767668
DOWNLOAD EBOOK →Nucleic acids have structurally evolved over billions of years to effectively store and transfer genetic information. In the 1980s, Nadrian Seeman’s idea of constructing a 3D lattice from DNA led to utilizing DNA as nanomolecular building blocks to create emergent molecular systems and nanomaterial objects. This bottom-up approach to construct nanoscale architectures with DNA marked the beginning of a new field, DNA nanotechnology, contributing significantly to the broad area of nanoscience and nanotechnology. The molecular architectonics of small "designer" molecules and short DNA sequences through complementary binding interaction engenders well-defined functional nanoarchitectures with realistic applications in areas ranging from biology to materials science and is termed "DNA nanoarchitectonics." This book discusses novel approaches adapted by leading researchers from all over the world to create functional nucleic acid molecular systems and nanoarchitectures. Individual chapters contributed by active practitioners provide fundamental and advanced knowledge emanated from their own and others’ work. Each chapter includes numerous illustrations, historical perspectives, case studies and practical examples, critical discussions, and future prospects. This book can serve as a practical handbook or as a textbook for advanced undergraduate- and graduate-level students of nanotechnology and DNA nanotechnology, supramolecular chemistry, and nanoarchitectonics and researchers working on macromolecular science, nanotechnology, chemistry, biology, and medicine, especially those with an interest in sensors, biosensors, nanoswitches and nanodevices, diagnostics, drug delivery, and therapeutics.
Author: Bernard R. Glick
Publisher:
Published: 1998
Total Pages: 724
ISBN-13:
DOWNLOAD EBOOK →The second edition explains the principles of recombinant DNA technology as well as other important techniques such as DNA sequencing, the polymerase chain reaction, and the production of monclonal antibodies.
