Immune Responses to Biosurfaces

Immune Responses to Biosurfaces PDF

Author: John D. Lambris

Publisher: Springer

Published: 2015-08-25

Total Pages: 247

ISBN-13: 3319186035

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​The collection of chapters in this proceedings volume brings together research from academic and industry scientists and clinical development experts who are focused on contemporary and emerging aspects of improving treatments employing biosurfaces. Interactions between biomaterial implants, devices, cell therapies, and whole organ transplants frequently trigger activation of body defense systems and responses that negatively affect the clinical outcome. Optimal tissue integration and modulation of foreign body reactions is therefore essential for preserving anticipated functions and avoiding adverse effects. Topics covered include mechanistic and applied research within the fields of extracorporeal devices, soft and hard tissue implants, tissue and biomaterial-targeting, therapeutic modulation of foreign body reactions, cell encapsulations, as well as cell and whole organ transplantation.

Biosurfaces

Biosurfaces PDF

Author: Kantesh Balani

Publisher: John Wiley & Sons

Published: 2015-01-26

Total Pages: 397

ISBN-13: 1118950631

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Ideal as a graduate textbook, this title is aimed at helping design effective biomaterials, taking into account the complex interactions that occur at the interface when a synthetic material is inserted into a living system. Surface reactivity, biochemistry, substrates, cleaning, preparation, and coatings are presented, with numerous case studies and applications throughout. Highlights include: Starts with concepts and works up to real-life applications such as implantable devices, medical devices, prosthetics, and drug delivery technology Addresses surface reactivity, requirements for surface coating, cleaning and preparation techniques, and characterization Discusses the biological response to coatings Addresses biomaterial-tissue interaction Incorporates nanomechanical properties and processing strategies

Biosurfaces

Biosurfaces PDF

Author: Kantesh Balani

Publisher: John Wiley & Sons

Published: 2015-01-23

Total Pages: 465

ISBN-13: 111895064X

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Ideal as a graduate textbook, this title is aimed at helping design effective biomaterials, taking into account the complex interactions that occur at the interface when a synthetic material is inserted into a living system. Surface reactivity, biochemistry, substrates, cleaning, preparation, and coatings are presented, with numerous case studies and applications throughout. Highlights include: Starts with concepts and works up to real-life applications such as implantable devices, medical devices, prosthetics, and drug delivery technology Addresses surface reactivity, requirements for surface coating, cleaning and preparation techniques, and characterization Discusses the biological response to coatings Addresses biomaterial-tissue interaction Incorporates nanomechanical properties and processing strategies

Current Research in Pulsed Laser Deposition

Current Research in Pulsed Laser Deposition PDF

Author: Liviu Duta

Publisher: MDPI

Published: 2021-08-30

Total Pages: 224

ISBN-13: 3036510443

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Despite its limitation in terms of surface covered area, the PLD technique still gathers interest among researchers by offering endless possibilities for tuning thin film composition and enhancing their properties of interest due to: (i) the easiness of a stoichiometric transfer even for very complex target materials, (ii) high adherence of the deposited structures to the substrate, (iii) controlled degree of phase, crystallinity, and thickness of deposited coatings, (iv) versatility of the experimental set-up which allows for simultaneous ablation of multiple targets resulting in combinatorial maps or consecutive ablation of multiple targets producing multi-layered structures, and (v) adjustment of the number of laser pulses, resulting in either a spread of nanoparticles, islands of materials or a complete covering of a surface. Moreover, a variation of PLD, known as Matrix Assisted Pulsed Laser Evaporation, allows for deposition of organic materials, ranging from polymers to proteins and even living cells, otherwise difficult to transfer unaltered in the form of thin films by other techniques. Furthermore, the use of laser light as transfer agent ensures purity of films and pulse-to-pulse deposition allows for an unprecedented control of film thickness at the nm level. This Special Issue is a collection of state-of-the art research papers and reviews in which the topics of interest are devoted to thin film synthesis by PLD and MAPLE, for numerous research and industry field applications, such as bio-active coatings for medical implants and hard, protective coatings for cutting and drilling tools withstanding high friction and elevated temperatures, sensors, solar cells, lithography, magnetic devices, energy-storage and conversion devices, controlled drug delivery and in situ microstructuring for boosting of surface properties.

Magnetic Sensors and Actuators in Medicine

Magnetic Sensors and Actuators in Medicine PDF

Author: Horia Chiriac

Publisher: Woodhead Publishing

Published: 2023-07-15

Total Pages: 475

ISBN-13: 0128236000

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Magnetic Sensors and Actuators in Medicine: Materials, Devices, and Applications provides an overview of the various sensors and actuators, their characteristics, role in the development of medical applications, the medical problems they solve, and future directions. The book brings together recent advances in the physics, chemistry and engineering of magnetic materials related to sensors and actuators that improve their functions in medical applications. The book describes the main applications of magnetic sensors and actuators, starting from the common and emerging magnetic materials, their principles of operation, the medical problems that they are used to address, and the latest achievements in the field. Reviews a wide range of magnetic sensors and actuators employed in medical applications such as diagnosis, surgery and therapy Describes magnetic material-based sensors and actuators, including their operation principles, properties and optimization for specific applications Includes examples of recent advances, such as emerging magnetic materials, magnetic nanowires, nanorods and/or nanotubes

Handbook of Biomaterials Biocompatibility

Handbook of Biomaterials Biocompatibility PDF

Author: Masoud Mozafari

Publisher: Woodhead Publishing

Published: 2020-06-17

Total Pages: 759

ISBN-13: 0081029683

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Handbook of Biomaterials Biocompatibility is a systematic reference on host response to different biomaterials, taking into account their physical, mechanical and chemical properties. The book reviews recent progress in the design and study of biomaterials biocompatibility, along with current understanding on how to control immune system response. Sections provide the fundamental theories and challenges of biomaterials biocompatibility, the role of different biomaterials physicochemical surface properties on cell responses, cell responses to different physicochemical properties of polymers, ceramics, metals, carbons and nanomaterials, and biomaterials in different tissues, such as the cardiac, nervous system, cartilage and bone. This resource will be suitable for those working in the fields of materials science, regenerative engineering, medicine, medical devices and nanotechnology. Reviews the fundamental theories and challenges of biomaterials biocompatibility, including an overview of the standards and regulations Provides an overview on the cellular and molecular mechanisms involved in host responses to biomaterials Systematically looks at cellular response and tissue response to a wide range of biomaterials, including polymers, metals, ceramics, alloys and nanomaterials

Wound Healing Biomaterials - Volume 2

Wound Healing Biomaterials - Volume 2 PDF

Author: Magnus Ågren

Publisher: Woodhead Publishing

Published: 2016-05-30

Total Pages: 542

ISBN-13: 0081006063

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Wound Healing Biomaterials: Volume Two, Functional Biomaterials discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal wounds opening up a new area of research in biomaterials and the ways they can be applied to the challenges associated with wound care. Much research is now concerned with new therapies, regeneration methods, and the use of biomaterials that can assist in wound healing and alter healing responses. This book provides readers with a thorough review of the functional biomaterials used for wound healing, with chapters discussing the fundamentals of wound healing biomaterials, films for wound healing applications, polymer-based dressing for wound healing applications, and functional dressings for wound care. Includes more systematic and comprehensive coverage on the topic of wound care Provides thorough coverage of all specific therapies and biomaterials for wound healing Contains clear layout and organization that is carefully arranged with clear titles and comprehensive section headings Details specific sections on the fundamentals of wound healing biomaterials, films for wound healing applications, polymer-based dressing for wound healing applications, and more