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Immune Response and the Eye

Author: J. Wayne Streilein

Publisher: Karger Medical and Scientific Publishers

Published: 1999-01-01

Total Pages: 239

ISBN-13: 3805568932

In this book, the physiologic bases of ocular immune privilege and the distinctive systemic immune responses elicited by eye derived antigens are described. Several chapters discuss the pathogeneses of these disorders which arise from infections, autoimmunity, and neoplasms. Finally, chapters devoted to corneal and retinal transplantation describe attempts to exploit ocular immune privilege to promote graft survival and thereby cure blindness. Ophthalmologists, both clinicians and physician scientists, general and tumor immunologists, transplantation biologists and anyone seeking to understand the immunopathogenic diseases that threaten vision will appreciate the information presented in this book.

Innate Immunity and the Eye

Author: Manfred Zierhut

Publisher: JP Medical Ltd

Published: 2013-04-30

Total Pages: 246

ISBN-13: 9350903091

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The innate immune system comprises the cells and mechanisms that are the first line of defence against infection by other organisms. This book provides a comprehensive synopsis of eye diseases, their immunological mechanisms and the role of the immune cells and mediators. Beginning with an introduction to the role of the innate immune system, the following chapters discuss the different types of immune cells in the eye and their role in the etiopathogenesis of various diseases including glaucoma and age-related macular degeneration. Edited by Manfred Zierhut, recognised expert from the University of Tuebingen Germany, this book is presented in an easy to read format, enabling practitioners to understand even the most sophisticated eye disorders from an immunological perspective. Key points Comprehensive synopsis of the role of the innate immune system in eye diseases Covers different types of immune cells Edited by internationally recognised specialist in Germany

Immune Response and the Eye

Author: Jerry Y. Niederkorn

Publisher: Karger Medical and Scientific Publishers

Published: 2007-01-01

Total Pages: 357

ISBN-13: 3805581874

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In memory of J. Wayne Streilein, the pioneer in ocular immunology The second edition of Immune Response and the Eye' highlights recent insights into the dangerous compromise' between the immune system and the eye, which protects the eye against pathogens while limiting inflammation and immune-mediated injury to ocular tissues with little or no regenerative potential. It discusses the broad spectrum of physiological, immunological, anatomical, and biochemical adaptations that conspire to closely regulate the tone and tenor of immune responses in the eye. This volume further describes immune-mediated diseases that occur when the compromise between the immune system and the eye is breached. This breakdown in immune privilege threatens the vision of millions each year. Finally, recent advances in ocular immunology are presented, which offer potential therapeutic applications in corneal and retinal transplantation and in the management of blinding autoimmune diseases of the eye. Eye researchers, ophthalmologists and immunologists will appreciate the state-of-the-art and authoritative information presented in Immune Response and the Eye'

Immunology, Inflammation and Diseases of the Eye

Author: Darlene A. Dartt

Publisher: Academic Press

Published: 2011-05-05

Total Pages: 452

ISBN-13: 0123819741

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This selection of articles from the Encyclopedia of the Eye provides a comprehensive overview of immunological features, diseases and inflammation of the eye and its support structures and organs. Rather than taking an immunological focus that is strictly suitable for clinicians, the volume offers a considerable basic science background and addresses a broad range of topics - the immune system of the eye, its various disorders, mechanisms of inflammation of the eye and visual system, treatment, wound healing mechanisms, stem cells, and more. The first single volume to integrate comparative studies into a comprehensive resource on the neuroscience of ocular immunology Chapters are carefully selected from the Encyclopedia of the Eye by the world's leading vision researchers The best researchers in the field provide their conclusions in the context of the latest experimental results

Whitcup and Nussenblatt's Uveitis

Author: Scott M. Whitcup

Publisher: Elsevier Health Sciences

Published: 2021-03-31

Total Pages: 432

ISBN-13: 0323789595

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Comprehensive and readable, Whitcup and Nussenblatt's Uveitis, 5th Edition, covers every aspect of this complex subspecialty in a single convenient volume. This clinically relevant guide covers the medical, pharmacological, and surgical treatment of uveitis in a visually rich, full-color format, offering a complete overview for today’s clinicians. New and updated case studies, key points boxes, and more than 400 images and graphics highlight major clinical points and provide insight into real situations that you can apply in practice. Features multiple chapters on diagnostic approach to help you meet the challenge of making accurate diagnoses. Reflects advancements and new developments on all aspects of uveitis including new medical and surgical treatments. Covers key topics such as the use of PCR in diagnostic testing, cataract surgery in patients with uveitis, the use of OCT in diagnosis and treatment, new infectious causes of uveitis (including Zika and Ebola), and novel treatments for inflammatory eye disease. Includes new clinical photographs, illustrations, and OCT images throughout. Reviews new randomized clinical trials of new uveitis therapy, as well as the approach to patients with HIV and HIV-associated ocular diseases including CMV retinitis and immune recovery uveitis. Provides expanded information on masquerade syndromes with important tips on diagnosis and management of intraocular lymphoma.

Immunology of Eye Diseases

Author: S. Lightman

Publisher: Springer

Published: 2011-10-05

Total Pages: 172

ISBN-13: 9789401076234

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The eye can become involved in immune-mediated diseases that affect it alone or as part of a multi-organ disease process. Much immunological attention has been focused on other organs affected by these processes and the subject of the immunology of eye diseases is a relatively new one. Many of these diseases that involve the eye are not life-threatening but can result in devastat ing loss of sight that if bilateral, will have major effects on the patient's life. Systemic immunological investigations are generally unhelpful in these patients and one of the major problems in this field has been the lack of diseased tissue available for examination to determine the pathological processes involved. Our poor understanding of basic mechanisms of disease in the eye has meant that treatment of many of these conditions is often inadequate. It has become possible to apply in the eye many ofthe techniques used to investigate the role of the immune system in other systems. Animal models of many of the disease processes have also allowed dissection of the immune response both within and outside the eye. It is my belief that a greater understanding of the mechanisms by which the structures in the eye become damaged will allow more specific and effective therapeutic strategies to be devised.

Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2

Author: David A. Sullivan

Publisher: Springer Science & Business Media

Published: 1998

Total Pages: 1090

ISBN-13: 9780306458125

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Harvard Medical School, Boston, MA. Proceedings of the Second International Conference on the Lacrimal Gland, Tear Film, and Dry Eye Syndromes, held November 16-19, 1996, at the Southampton Princess Resort, Bermuda. DNLM: Lacrimal Apparatus--congresses.

Ocular Immunology in Health and Disease

Author: Steven B. Koevary

Publisher:

Published: 1999

Total Pages: 212

ISBN-13:

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Provides detailed information about ocular immunity and the basis of ocular immune privilege, and elaborates on the role of immune effector mechanisms in specific ocular conditions. Offers a detailed overview of immune system function, discusses autoimmune diseases and allergic conditions affecting the eye and their treatment, reviews the immunology of corneal graft rejection, and discusses the immune system's role in ocular tumor elimination and corneal transplant. Annotation copyrighted by Book News, Inc., Portland, OR

Immunology at Eye Level

Author: Chelsea M Higgins

Publisher:

Published: 2020-04-25

Total Pages: 80

ISBN-13:

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Immunology at Eye Level is a comprehensive, basic guide to the immune system. Whether you are a parent researching how vaccines work, a student looking for a guide, or a patient trying to understand a diagnosis, this book can help. The book uses art and prose to explain concepts, making a complex issue easy to understand.

Common Eye Infections

Author: Imtiaz Chaudhry

Publisher: BoD – Books on Demand

Published: 2013-05-08

Total Pages: 268

ISBN-13: 953510926X

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Since ocular infections are one of the most frequent occurrences in ophthalmology, the treatment for these infections must be fast, precise and effective. In order to address this goal, it is important to identify and characterize the culprit microorganisms involved in the pathogenesis of ocular infections. Clinical diagnosis of ocular infections can be confirmed by several techniques based on microbiological test of ocular samples. Some of these techniques include classic microbiological testing in which it is necessary to isolate microorganisms to characterize them by biochemical analysis which require significant resources and timing.