Podocytopathy

Podocytopathy PDF

Author: Z.-H. Liui

Publisher: Karger Medical and Scientific Publishers

Published: 2014-05-16

Total Pages: 274

ISBN-13: 3318026514

DOWNLOAD EBOOK →

The podocyte is a key cell that forms the last barrier of the kidney filtration unit. One of the most exciting developments in the field of nephrology in the last decade has been the elucidation of its biology and its role in the pathophysiology of inherited and acquired glomerular disease, termed podocytopathy. In this publication, world-renowned experts summarize the most recent findings and advances in the field: they describe the unique biological features and injury mechanisms of the podocyte, novel techniques used in their study, and diagnosis and potential therapeutic approaches to glomerular diseases. Due to its broad scope, this publication is of great value not only for clinical nephrologists and researchers, but also for students, residents, fellows, and postdocs.

Glomerulonephritis

Glomerulonephritis PDF

Author: Howard Trachtman

Publisher: Springer

Published: 2019-04-08

Total Pages: 0

ISBN-13: 9783319493787

DOWNLOAD EBOOK →

This Handbook serves as a convenient, state-of-the-art and comprehensive resource on the pathogenesis, diagnosis, and treatment of glomerular diseases. Clinical approaches, modalities and challenges are provided, along with new developments since the publication of Kidney Disease Improving Global Outcomes (KDIGO): Glomerulonephritis. Chapters dedicated to glomerular diseases mirror the current classification schemes used by Nephrologists and Pathologists and will include definition and natural history, epidemiology, clinical manifestations, pathology, diagnosis, differential diagnosis, treatment (algorithms when appropriate), prognosis and future prospects and current direction of research. Contributing authors consist of internationally renowned glomerulonephritis experts, renal pathologists and clinical nephrologists who are engaged in the management of glomerular diseases in clinical pediatric and internal medicine practices. Glomerulonephritis fills a considerable knowledge gap for general nephrologists, providers involved with the care of patients with glomerular diseases, and researchers. It should also be of value to medical students, interns, residents and fellows, as well as all clinicians engaged in medical education.

Recent Advances in IgA Nephropathy

Recent Advances in IgA Nephropathy PDF

Author: Kar Neng Lai

Publisher: World Scientific

Published: 2008-12

Total Pages: 440

ISBN-13: 9812835865

DOWNLOAD EBOOK →

IgA nephropathy is the most common primary glomerulonephritis in developed countries. The primary defect lies in the abnormalities of the IgA molecule. The disease affects all ages, mainly in the young adults, and may recur in a transplanted kidney.This outstanding volume provides a comprehensive overview of the advances in this disease over the last ten years. It covers the genetics, epidemiology, clinicopathological features, pathogenesis, prognostic mechanisms, and treatment of this unique disease. Twenty-seven chapters are written by 43 experts from 13 countries; these experts have been providing forefront scientific findings to the scientific community for the last 20 years. The book covers all clinical, pathological and molecular aspects of IgA nephropathy. This is an essential source of reference for nephrologists, internists, pathologists, and molecular biologists. It is also suitable reading for graduate students or research scientists in the field of kidney diseases.

Pathogenesis and Treatment in IgA Nephropathy

Pathogenesis and Treatment in IgA Nephropathy PDF

Author: Yasuhiko Tomino

Publisher: Springer

Published: 2016-03-10

Total Pages: 342

ISBN-13: 4431555889

DOWNLOAD EBOOK →

This book discusses the latest findings on the pathogenesis and treatment of IgA nephropathy. It particularly focuses on recently recognized initiation and progression factors and the varying treatment strategies in different regions, such as Asia, Europe, and the United States. More than 40 years have passed since Dr. Jean Berger first described primary IgA nephropathy (“Nephropathy with mesangial IgA-IgG deposits”) as a new disease entity. Immunohistopathologically, IgA nephropathy is characterized by the granular deposition of IgA (IgA1) and C3 in the glomerular mesangial areas with mesangial cell proliferation and the expansion of mesangial matrices. It is clear that IgA nephropathy is one of the most common types of chronic glomerulonephritis in the world. This disease may lead to end-stage kidney disease, with its enormous economic impact on healthcare everywhere. Efforts by many investigators around the world have gradually clarified various aspects of the pathogenesis and treatment of IgA nephropathy. However, there are many controversial strategies for the treatment of patients with IgA nephropathy throughout the world, as there are several limitations for treatment in each country. This volume provides nephrologists everywhere with an overview and comparison of both global and regional findings in basic and clinical fields in IgA nephropathy. It covers genetic variation, aberrant IgA1 production, and classification etiology, guidelines, and treatment goals, with all chapters written by top international researchers.

Vaccine Adjuvants and Delivery Systems

Vaccine Adjuvants and Delivery Systems PDF

Author: Manmohan Singh

Publisher: John Wiley & Sons

Published: 2007-08-03

Total Pages: 470

ISBN-13: 0470134925

DOWNLOAD EBOOK →

The authoritative reference on recent developments in vaccinology New technologies, including recombinant protein and DNA, have sparked phenomenal progress in vaccine development and delivery systems. This unique resource brings scientists up to date on recent advances and provides the information they need to select candidate adjuvants. With chapters written by leading experts in their fields, Vaccine Adjuvants and Delivery Systems: * Provides a comprehensive overview of the rapidly evolving field and developing formulation methods * Covers cutting-edge technologies and gives the current status of adjuvants in clinical trials and those still in the pre-clinical stage * Includes detailed information on specific vaccine adjuvants, including MF59, TLR4 agonists, new iscoms, cytokines, polyphosphazenes, and more * Provides a historical perspective on the development of vaccine adjuvants and discusses the mechanisms of adjuvant actions * Covers some novel adjuvants and delivery systems and the safety evaluation of adjuvants A great reference for researchers, scientists, and students in vaccinology, biotechnology, immunology, and molecular biology, this resource is also valuable for researchers and scientists in veterinary medicine who work to prevent diseases in animals.

Adolescents with Chronic Kidney Disease

Adolescents with Chronic Kidney Disease PDF

Author: Maha N. Haddad

Publisher: Springer

Published: 2018-10-05

Total Pages: 283

ISBN-13: 3319972200

DOWNLOAD EBOOK →

End-stage renal disease is a devastating diagnosis to the patient, family and their care provider. This book covers all aspects of chronic kidney disease from a general description to its psychological impact on the adolescent and lastly its progression to end-stage and dialysis. It details the important aspects of the patient’s journey from diagnosis to their final destination including transplant and discussion of the medications used. It includes chapters on important etiologies of chronic kidney disease in adolescence, addressing the particular challenges a provider may be faced with in caring for this age group, and finally transition of their care to adult care providers. Written by experts in the field of pediatrics and nephrology Adolescents with Chronic Kidney Disease is the definitive resource in diagnosing and transitioning patients with chronic kidney disease.

Lanterna Rally - Theme by Grace Themes