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Evaluating Human Genetic Diversity
Author: National Research Council
Publisher: National Academies Press
Published: 1998-01-19
Total Pages: 101
ISBN-13: 0309184746
DOWNLOAD EBOOK →This book assesses the scientific value and merit of research on human genetic differencesâ€"including a collection of DNA samples that represents the whole of human genetic diversityâ€"and the ethical, organizational, and policy issues surrounding such research. Evaluating Human Genetic Diversity discusses the potential uses of such collection, such as providing insight into human evolution and origins and serving as a springboard for important medical research. It also addresses issues of confidentiality and individual privacy for participants in genetic diversity research studies.
Human Populations, Genetic Variation, and Evolution
Author: Laura Newell Morris
Publisher:
Published: 1973
Total Pages: 500
ISBN-13: 9780700202126
DOWNLOAD EBOOK →Human Variation
Author: Aravinda Chakravarti
Publisher:
Published: 2014
Total Pages: 0
ISBN-13: 9781621820901
DOWNLOAD EBOOK →"A subject collection from Cold Spring Harbor perspectives in medicine."
Genetic Variation and Its Maintenance
Author: Derek Frank Roberts
Publisher: Cambridge University Press
Published: 1986-10-30
Total Pages: 318
ISBN-13: 9780521332576
DOWNLOAD EBOOK →This volume considers the genetic variability of human populations, particularly in the tropics: its origins and maintenance, and its contribution to the phenotypic variability of complex characters. The first section deals with the ways of analysing genetic variation and provides a valuable review of relevant developments in molecular biology. The origin and maintenance of genetic diversity is considered in the second section with data presented for Pacific, African, Asian and Central American populations. The final section concerns characters in which the genetic contribution to variability is complex and shows how such characters may be used to elucidate biological problems of affinity and differentiation, of adaptation and survival. Published as part of the Decade of the Tropics research programme of the International Union of Biological Sciences, this volume will be of particular interest to human geneticists, physical and biological anthropologists.
Human Evolutionary Genetics
Author: Mark Jobling
Publisher: Garland Science
Published: 2013-06-25
Total Pages: 689
ISBN-13: 131795226X
DOWNLOAD EBOOK →Human Evolutionary Genetics is a groundbreaking text which for the first time brings together molecular genetics and genomics to the study of the origins and movements of human populations. Starting with an overview of molecular genomics for the non-specialist (which can be a useful review for those with a more genetic background), the book shows h
Human Population Genetics and Genomics
Author: Alan R. Templeton
Publisher: Academic Press
Published: 2018-11-08
Total Pages: 498
ISBN-13: 0123860261
DOWNLOAD EBOOK →Human Population Genetics and Genomics provides researchers/students with knowledge on population genetics and relevant statistical approaches to help them become more effective users of modern genetic, genomic and statistical tools. In-depth chapters offer thorough discussions of systems of mating, genetic drift, gene flow and subdivided populations, human population history, genotype and phenotype, detecting selection, units and targets of natural selection, adaptation to temporally and spatially variable environments, selection in age-structured populations, and genomics and society. As human genetics and genomics research often employs tools and approaches derived from population genetics, this book helps users understand the basic principles of these tools. In addition, studies often employ statistical approaches and analysis, so an understanding of basic statistical theory is also needed. Comprehensively explains the use of population genetics and genomics in medical applications and research Discusses the relevance of population genetics and genomics to major social issues, including race and the dangers of modern eugenics proposals Provides an overview of how population genetics and genomics helps us understand where we came from as a species and how we evolved into who we are now
Populations Genetics of Humans
Author: Christine Langhoff
Publisher: GRIN Verlag
Published: 2003-06-07
Total Pages: 11
ISBN-13: 3638195244
DOWNLOAD EBOOK →Essay from the year 2002 in the subject Biology - Genetics / Gene Technology, grade: 2.1 (B), Oxford University (New College), language: English, abstract: The aim of population genetics is to model the dynamics of evolutionary change within and between populations i.e. a group of individuals who exist together in time and space and are capable of interbreeding. In human DNA approximately 0.08% of the nucleotide base pairs varies among individuals and thus populations genetics has been trying to establish why this is so. Four basic evolutionary forces responsible for genetic diversity in populations have been identified: mutation, natural selection, genetic drift and gene flow. Mutations are copying errors during DNA replication and transcriptions, which introduce new alleles into the population. Natural selection is the differential transmission of alleles into the next generation due to the consequences of functional differences on an individual’s survival and reproductive success. Genetic drift is the differential transmission of alleles into the next generation as a result of random sampling and has the greatest potential impact in small populations. Gene flow spreads alleles from one population into another via migration, making them more genetically similar to each other, and countering genetic differentiation by drift. I am going to examine the contribution of genetic drift, gene flow and natural selection to the levels of diversity and composition of genetic polymorphisms in different human populations. Further I am going to examine why some populations have greater diversity than others and compare the patterns of genetic diversity of humans and chimpanzees.
In the Light of Evolution
Author: National Academy of Sciences
Publisher: Sackler Colloquium
Published: 2007
Total Pages: 388
ISBN-13:
DOWNLOAD EBOOK →The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, four or five such colloquia are scheduled, typically two days in length and international in scope. Colloquia are organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. Colloquia presentations are recorded and posted on the National Academy of Sciences Sackler colloquia website and published on CD-ROM. These Colloquia are made possible by a generous gift from Mrs. Jill Sackler, in memory of her husband, Arthur M. Sackler.
Variation in the Human Genome
Author: Derek J. Chadwick
Publisher: John Wiley & Sons
Published: 2008-04-30
Total Pages: 340
ISBN-13: 0470514892
DOWNLOAD EBOOK →The mapping of human genes is proceeding rapidly. Genes associated with specific inherited diseases are being identified, often providing insight into the molecular cause of the disease. At the moment, however, little consideration is being given to the variation present in different human populations. Variation in the Human Genome discusses methods of analysing population genetic data and how contemporary genetic heterogeneity arises during the evolution and migration of human populations. Specific disorders such as cystic fibrosis, beta-thalassaemia, fragile X, phenylketonuria and tumour development susceptibility are used to illustrate this genetic variability and mechanisms of gene mutation and evolution.
