Human Implantation

Human Implantation PDF

Author: Y. W. Loke

Publisher: Cambridge University Press

Published: 1995-11-30

Total Pages: 332

ISBN-13: 9780521441933

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This book explains and reviews some of the significant events involved in human implantation and the establishment of the placenta in the uterus. This critical phase in human reproduction has proved to be an elusive and challenging area of research, not least because of the immunological and genetic interactions between the mother and fetus. The volume focuses on the most recent advances in our understanding of the basic mechanisms involved, with a particular emphasis on cell biology and immunology. This lucid volume will benefit all those studying and undertaking research in reproductive biology and immunology, perinatal pathology, fetal medicine and obstetrics.

Immunology of Pregnancy

Immunology of Pregnancy PDF

Author: Gil Mor

Publisher: Springer Science & Business Media

Published: 2007-12-27

Total Pages: 338

ISBN-13: 0387349448

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This book covers in detail contemporary hypotheses and studies related to the immunology of implantation and provides a practical approach for the application of basic reproductive immunology research to pregnancy complications such as preeclampsia, pre-term labor and IUGR. Provides complete and up to date review of current knowledge of the role of the immune system during pregnancy and the interactions between the placenta and the maternal immune system.

Scientific and Medical Aspects of Human Reproductive Cloning

Scientific and Medical Aspects of Human Reproductive Cloning PDF

Author: National Research Council

Publisher: National Academies Press

Published: 2002-06-17

Total Pages: 295

ISBN-13: 0309076374

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Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.

How to Prepare the Endometrium to Maximize Implantation Rates and IVF Success

How to Prepare the Endometrium to Maximize Implantation Rates and IVF Success PDF

Author: Gabor Kovacs

Publisher: Cambridge University Press

Published: 2019-01-17

Total Pages: 217

ISBN-13: 1108244386

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The last step in the IVF treatment cycle, embryo transfer, is also the process with the highest failure rate. No matter how good the laboratory technique is, a successful pregnancy will not be achieved without meticulous preparation of the uterus to accept the embryo. This book reviews the scientific evidence on endometrial receptivity, including histological, hormonal, biochemical, and immunological factors. Practical and concise, it supports gynecologists and embryologists to make evidence-based decisions that can influence the success rates of implantation and live births. Part of a series of books offering treatments and strategies for fertility and conception to optimize IVF outcomes, this volume is for all clinicians and embryologists working in reproductive medicine.

Stem Cells and the Future of Regenerative Medicine

Stem Cells and the Future of Regenerative Medicine PDF

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2002-01-25

Total Pages: 112

ISBN-13: 0309170427

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Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Regulation of Implantation and Establishment of Pregnancy in Mammals

Regulation of Implantation and Establishment of Pregnancy in Mammals PDF

Author: Rodney D. Geisert

Publisher: Springer

Published: 2015-10-08

Total Pages: 271

ISBN-13: 3319158562

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Over the past few decades technological advances in transcriptomics, proteomics, metabolomics, and glycomics along with the ability to selectively knockout genes of interest has greatly advanced our understanding of maternal-conceptus interactions that are essential for the establishment and maintenance of a successful pregnancy. This knowledge provides a foundation from which to build research endeavors to help resolve infertility, embryonic loss and recurrent abortion in humans, captive wild animals and important farm species. The present volume on “Regulation of Implantation and Establishment of Pregnancy in Mammals” brings together current reviews from leading experts to address the diversity of mechanisms by which species establish and maintain pregnancy. Implantation in rodents, dogs, pigs, cattle, sheep, horses, primates, humans and embryonic diapause in wild species are discussed. Reviews will provide current knowledge on the role of endometrial steroid receptors, adhesion factors, cytokines, interferons, steroids, prostaglandins, growth factors and immune cells involved with regulation of conceptus development.

Embryo Implantation

Embryo Implantation PDF

Author: Daniel D. Carson

Publisher: Springer Science & Business Media

Published: 1999-09-24

Total Pages: 336

ISBN-13: 9780387988061

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This volume contains the proceedings of the International Symposium on Embryo Implantation: Molecular, Cellular and Clinical Aspects, held from October 3-6, 1997 in Newport Beach, California. Internationally recognized experts discuss the development and future of human in vitro fertilization and embryo implantation, the cellular aspects of implantation, hormonal regulation, molecular markers of receptivity, trophoblast factors, primate models and animal studies, and transcriptional regulation of maternal-fetal recognition.

Implantation and Early Pregnancy in Humans

Implantation and Early Pregnancy in Humans PDF

Author: E.R. Barnea

Publisher: CRC Press

Published: 1993-11-15

Total Pages: 536

ISBN-13: 9781850705130

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Over the last two decades, major advances in ovulation induction and assisted reproductive technologies have been made, and now, in the 1990s, the aim is to concentrate talent and efforts on the next obvious step - achieving a high rate of successful full-term pregnancies by concentrating on implantation and early pregnancy. Investigating and surmounting the disorders associated with this critical period are the major hurdles, which, through research and clinical efforts, must be overcome in order to achieve this goal.