Centers of the Cancer Universe

Centers of the Cancer Universe PDF

Author: Donald L. Trump

Publisher: Rowman & Littlefield

Published: 2021-10-11

Total Pages: 313

ISBN-13: 1538144905

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A 2022 Choice Reviews Outstanding Academic Title An important history of the development of cancer centers of excellence and the revolution in cancer treatment. In the 1960s a coalition of concerned citizens, scientists and politicians joined forces to convince the federal government to focus its efforts on conquering cancer. The National Cancer Act of 1971 resulted and was signed into law on December 23, 1971 by President Nixon. The national “War on Cancer,” was declared with some leaders naively arguing that the disease would be conquered by the nation’s bicentennial—a mere five years in the future. Over the next five decades scientific discoveries demonstrated the great complexity of what had formerly been thought of as a single disease – with the advent of the genetic characterization of cancers, it is now recognized that there are almost an infinite number of cancers as defined by their many genetic mutations. The National Cancer Act established the infrastructure for the designation of centers by the National Cancer Institute (NCI) and these centers have evolved into models of multidisciplinary, collaborative cancer research, treatment and prevention contributing to a reduction in cancer mortality and increase in quality of life and survival that has translated into more than 17 million cancer survivors in the United States in 2021. Centers of the Cancer Universe: A Half-Century of Progress Against Cancer tells the story of how cancer research was not front and center at most universities and research institutions before the National Cancer Act of 1971, and why many physicians were reluctant even to treat patients with cancer in the early 20th century. It follows the behind-the-scenes lobbying, resistance and negotiating that preceded signing the Act into law, and how the cancer centers of today came to fruition, and shaped how cancer research, clinical trials and treatment would be conducted.

Pancreatic Cancer

Pancreatic Cancer PDF

Author: National Cancer Institute

Publisher: CreateSpace

Published: 2012-06-23

Total Pages: 80

ISBN-13: 9781478117353

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The National Cancer Institute's Pancreatic Cancer: A Summary of NCI's Portfolio and Highlight of Recent Research Progress provides a retrospective analysis of progress such as trends in numbers of NCI-funded pancreatic cancer research projects, publications, initiatives, and clinical trials. In 2000, the National Cancer Institute (NCI) convened the Pancreatic Cancer Progress Review Group (PRG) to review the pancreatic cancer research field and make recommendations concerning the most urgent needs and promising directions for future NCI investment. The PRG's report, Pancreatic Cancer: An Agenda for Action provided priority recommendations in six major areas: Health of the Field and Overarching Issues; Tumor Biology; Risk, Prevention, Screening, and Diagnosis; Therapy; Health Services Research: Scientific Toolkit. In 2007, a Clinical Trials Planning Meeting on Pancreas Cancer Treatment was convened to discuss the integration of basic and clinical knowledge in design of clinical trials in pancreatic adenocarcinoma. A Consensus Report of the meeting published in November 2009 provided recommendations in the following emphasis areas: New Targets for Drug Development; Utility of Preclinical Models; Future Clinical Trials; Establishment of Biorepositories; Development of Biomarkers. NCI's efforts in pancreatic cancer research have increased our understanding of the biological basis for pancreatic cancer, developed potential means to reduce morbidity and mortality associated with the disease, and expanded pancreatic cancer research capacity. The following or some research highlights in the five key priority areas identified by the PRG: Tumor Biology – Research on the tumor biology of pancreatic cancer has increased understanding of factors critical to key steps in the progression of pancreatic cancers; Risk, Prevention, Screening, and Diagnosis – Results of NCI-sponsored research related to the risk, prevention, screening, and diagnosis of pancreatic cancer have identified potential markers associated with pancreatic cancer risk as well as potential diagnostic markers; Therapy – NCI-sponsored research on therapy for pancreatic cancer has investigated optimal timing, delivery, and drug combinations that may improve the treatment of pancreatic cancer.~

Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop

Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop PDF

Author: National Academies Of Sciences Engineeri

Publisher: National Academies Press

Published: 2021-11-02

Total Pages:

ISBN-13: 9780309136594

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New technologies and improved understanding of the genesis and progression of various cancers have added to the enthusiasm for potential new strategies to improve screening and early detection of cancer. Research is also under way to evaluate refinements in current screening approaches, including determining optimal screening intervals, the ages at which screening should begin and end, as well as more specific estimates of the potential risks and benefits of screening for certain populations, such as racial and ethnic minority populations and people who have elevated risk for specific cancers. However, there remain significant challenges to developing, validating, and effectively implementing new cancer screening approaches. Guidelines for screening issued by different organizations vary considerably with no clear way of deciding which guidelines are most trustworthy. There is also a need to improve access to high-quality cancer screening and follow-up care, particularly in low-resource communities and among populations who are underserved or have numerous barriers to receiving care. Â To examine the challenges and opportunities related to improving current approaches to cancer screening, as well as the evidence base for novel cancer screening methods, the National Cancer Policy Forum held a workshop, Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening, on March 2-3, 2020, in Washington, DC. This workshop convened a broad range of experts, including clinicians, researchers, statisticians, and patient advocates, as well as representatives of health care organizations, academic medical centers, insurers, and federal agencies. This publication summarizes the presentations and discussions of the workshop and highlights suggestions from individual participants regarding how to improve cancer screening.

The Cancer Atlas

The Cancer Atlas PDF

Author: Ahmedin Jemal

Publisher:

Published: 2015

Total Pages: 0

ISBN-13: 9781604432282

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This atlas illustrates the latest available data on the cancer epidemic, showing causes, stages of development, and prevalence rates of different types of cancers by gender, income group, and region. It also examines the cost of the disease, both in terms of health care and commercial interests, and the steps being taken to curb the epidemic, from research and screening to cancer management programs and health education.

Unraveling Cancer

Unraveling Cancer PDF

Author: Mustafa A B

Publisher: Mustafa A.B

Published: 2024-01-24

Total Pages: 0

ISBN-13:

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"Unraveling Cancer: Progress and Future Directions in Cancer Research" delves into the multifaceted nature of cancer, exploring its causes, types, signs and symptoms, detection and diagnosis, treatment, coping strategies, living with cancer, prevention measures, and future directions in cancer research. The book covers genetic, environmental, and lifestyle factors contributing to cancer development, different types of cancer, early warning signs and symptoms, screening and diagnostic tests, cancer stages, treatment modalities, coping strategies, survivorship, late effects of treatment, recurrence, prevention measures, and risk reduction strategies. The book also highlights future directions in cancer research, such as personalized medicine, immunotherapy, and precision medicine, which aim to tailor treatment to the individual's genetic makeup, harness the body's immune system to fight cancer, and use genomic sequencing to identify targeted therapies for cancer treatment."