Heterologous Immunity: Implications and Applications in Vaccines and Immunotherapies
Author: Babita Agrawal
Publisher: Frontiers Media SA
Published: 2020-08-27
Total Pages: 168
ISBN-13: 2889639657
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Pharmaceutical Biotechnology
Author: Daan J. A. Crommelin
Publisher: CRC Press
Published: 2002-11-14
Total Pages: 456
ISBN-13: 9780415285018
DOWNLOAD EBOOK →The field of pharmaceutical biotechnology is evolving rapidly. A whole new arsenal of protein pharmaceuticals is being produced by recombinant techniques for cancer, viral infections, cardiovascular and hereditary disorders, and other diseases. In addition, scientists are confronted with new technologies such as polymerase chain reactions, combinatorial chemistry and gene therapy. This introductory textbook provides extensive coverage of both the basic science and the applications of biotechnology-produced pharmaceuticals, with special emphasis on their clinical use. Pharmaceutical Biotechnology serves as a complete one-stop source for undergraduate pharmacists, and it is valuable for researchers and professionals in the pharmaceutical industry as well.
Immunization Safety Review
Author: Institute of Medicine
Publisher: National Academies Press
Published: 2002-07-02
Total Pages: 304
ISBN-13: 0309169887
DOWNLOAD EBOOK →By two years of age, healthy infants in the United States can receive up to 20 vaccinations to protect against 11 diseases. Although most people know that vaccines effectively protect against serious infectious diseases, approximately one-quarter of parents in a recent survey believe that infants get more vaccines than are good for them, and that too many immunizations could overwhelm an infant's immune system. The Immunization Safety Review Committee reviewed the evidence regarding the hypothesis that multiple immunizations increase the risk for immune dysfunction. Specifically, the committee looked at evidence of potential biological mechanisms and at epidemiological evidence for or against causality related to risk for infections, the autoimmune disease type 1 diabetes, and allergic disorders.
Mucosal Vaccines
Author: Hiroshi Kiyono
Publisher: Elsevier
Published: 1996-10-23
Total Pages: 501
ISBN-13: 0080537057
DOWNLOAD EBOOK →This comprehensive, authoritative treatise covers all aspects of mucosal vaccines including their development, mechanisms of action, molecular/cellular aspects, and practical applications. The contributing authors and editors of this one-of-a-kind book are very well known in their respective fields. Mucosal Vaccines is organized in a unique format in which basic, clinical, and practical aspects of the mucosal immune system for vaccine development are described and discussed. This project is endorsed by the Society for Mucosal Immunology. Provides the latest views on mucosal vaccines Applies basic principles to the development of new vaccines Links basic, clinical, and practical aspects of mucosal vaccines to different infectious diseases Unique and user-friendly organization
Chimpanzees in Biomedical and Behavioral Research
Author: National Research Council
Publisher: National Academies Press
Published: 2011-12-05
Total Pages: 200
ISBN-13: 0309220424
DOWNLOAD EBOOK →For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future.
Trained Immunity-based Vaccines
Author: Jose Luis Subiza
Publisher: Frontiers Media SA
Published: 2021-08-25
Total Pages: 195
ISBN-13: 2889712311
DOWNLOAD EBOOK →Dr. Jose Luis Subiza is the founder and CEO of Inmunotek SL. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Micro- and Nanotechnology in Vaccine Development
Author: Mariusz Skwarczynski
Publisher: William Andrew
Published: 2016-09-20
Total Pages: 462
ISBN-13: 0323400299
DOWNLOAD EBOOK →This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress. MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles. Provides a comprehensive and unparalleled overview of the role of micro- and nanotechnology in vaccine development Allows researchers to quickly familiarize themselves with the broad spectrum of vaccines and how micro- and nanotechnologies are applied to their development Includes a combination of overview chapters setting out general principles, and focused content dealing with specific vaccines, making it useful to readers from a variety of disciplines
Toll-Like Receptors (TLRs) and Innate Immunity
Author: Stefan Bauer
Publisher: Springer Science & Business Media
Published: 2007-12-11
Total Pages: 243
ISBN-13: 3540721673
DOWNLOAD EBOOK →Overall recent research on TLRs has led to tremendous increase in our understanding of early steps in pathogen recognition and will presumably lead to potent TLR targeting therapeutics in the future. This book reviews and highlights our recent understanding on the function and ligands of TLRs as well as their role in autoimmunity, dendritic cell activation and target structures for therapeutic intervention.
The Science and Applications of Synthetic and Systems Biology
Author: Institute of Medicine
Publisher: National Academies Press
Published: 2011-12-30
Total Pages: 570
ISBN-13: 0309219396
DOWNLOAD EBOOK →Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
Pediatric Vaccines and Vaccinations
Author: Timo Vesikari
Publisher: Springer
Published: 2017-11-01
Total Pages: 264
ISBN-13: 3319599526
DOWNLOAD EBOOK →This graduate textbook serves as a highly readable guide on vaccines and vaccination in infants, children and adolescents from an European perspective. The first part of the book is dedicated to childhood and adolescent vaccine schedules, maternal and neonatal immunization and safety of vaccines. In a second part we focus on viral and bacterial vaccines. Further chapters discuss pediatric travel vaccines, vaccines in the pipeline and the European registration process. This book is intended to be a reference textbook and will help to standardize the information on vaccines and immunization program in the WHO European Region.
