Heredity and Infection

Heredity and Infection PDF

Author: Jean-Paul Gaudilliére

Publisher: Routledge

Published: 2012-11-12

Total Pages: 402

ISBN-13: 1135138613

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Ideas about the transmission of disease have long formed the core of modern biology and medicine. Heredity and Infection examines their development over the last century. Two scientific revolutions - the bacteriological revolution of the 1890s and the genetic revolution at the start of the twentieth century - acted as the catalysts of major change in our understanding of the causes of illness. As well as being great scientific achievements, these were social and political watersheds that reconfigured the medical and administrative means of intervention. By establishing a clear distinction between transmission by infection and genetic transmission, this shift was instrumental in separating hygiene from eugenism. The authors argue that the popular perception of such a sharp divide stabilized only after 1945 when the use of antibiotics to end epidemics became commonplace. For health professionals the separation has never become an absolute one, and the book examines the various blends of heredity and infection that have preoccupied biology, medicine and the social sciences. Heredity and Infection recontructs the changing epidemiology of such historically important pathologies as tuberculosis , cancer and AIDS. In doing so, it demonstrates the role of experimental models, medical practices and cultural images in the making of contemporary biochemical knowledge.

Immunodeficient Rodents

Immunodeficient Rodents PDF

Author: Institute of Laboratory Animal Resour

Publisher: Legare Street Press

Published: 2023-07-18

Total Pages: 0

ISBN-13: 9781021229830

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This informative guide provides a comprehensive overview of the biology and care of immunodeficient rodents, which are essential for the study of human diseases and the development of new treatments. It is an invaluable resource for scientists, veterinarians, and animal care professionals. This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Susceptibility to Infectious Diseases

Susceptibility to Infectious Diseases PDF

Author: Richard Bellamy

Publisher: Cambridge University Press

Published: 2010-02-04

Total Pages: 0

ISBN-13: 9780521129596

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Written by recognized authorities, this book summarizes significant advances in understanding the complexity of host genetic susceptibility. Substantial progress has been made over the last ten years in identifying why some people are particularly susceptible to specific infectious diseases. Extensive evidence has also been accumulated to reveal that host genes are important determinants of the outcome of infection for many common pathogens. Diseases covered include those of great public health inportance such as malaria and HIV, as well as those of current topical interest such as Creutzfeldt-Jakob disease.

Genes, Behavior, and the Social Environment

Genes, Behavior, and the Social Environment PDF

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2006-12-07

Total Pages: 385

ISBN-13: 0309101964

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Over the past century, we have made great strides in reducing rates of disease and enhancing people's general health. Public health measures such as sanitation, improved hygiene, and vaccines; reduced hazards in the workplace; new drugs and clinical procedures; and, more recently, a growing understanding of the human genome have each played a role in extending the duration and raising the quality of human life. But research conducted over the past few decades shows us that this progress, much of which was based on investigating one causative factor at a time—often, through a single discipline or by a narrow range of practitioners—can only go so far. Genes, Behavior, and the Social Environment examines a number of well-described gene-environment interactions, reviews the state of the science in researching such interactions, and recommends priorities not only for research itself but also for its workforce, resource, and infrastructural needs.

She Has Her Mother's Laugh

She Has Her Mother's Laugh PDF

Author: Carl Zimmer

Publisher: Penguin

Published: 2018-05-29

Total Pages: 672

ISBN-13: 1101984600

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2019 PEN/E.O. Wilson Literary Science Writing Award Finalist "Science book of the year"—The Guardian One of New York Times 100 Notable Books for 2018 One of Publishers Weekly's Top Ten Books of 2018 One of Kirkus's Best Books of 2018 One of Mental Floss's Best Books of 2018 One of Science Friday's Best Science Books of 2018 “Extraordinary”—New York Times Book Review "Magisterial"—The Atlantic "Engrossing"—Wired "Leading contender as the most outstanding nonfiction work of the year"—Minneapolis Star-Tribune Celebrated New York Times columnist and science writer Carl Zimmer presents a profoundly original perspective on what we pass along from generation to generation. Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities... But, Zimmer writes, “Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are—our appearance, our height, our penchants—in inconceivably subtle ways.” Heredity isn’t just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors—using a word that once referred to kingdoms and estates—but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer’s lucid exposition and storytelling, this resounding tour de force delivers it. Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world’s best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.

Spreading Germs

Spreading Germs PDF

Author: Michael Worboys

Publisher: Cambridge University Press

Published: 2000-10-16

Total Pages: 358

ISBN-13: 9780521773027

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Spreading Germs discusses how modern ideas on the bacterial causes diseases were constructed and spread within the British medical profession.

Case Studies in Immunology

Case Studies in Immunology PDF

Author: Raif Geha

Publisher: Garland Science

Published: 2010-07-29

Total Pages: 353

ISBN-13: 113515306X

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This book presents case histories to illustrate in a clinical context essential points about the mechanisms of immunity. It includes cases that illustrate both recently discovered genetic immunodeficiencies and some more familiar and common diseases with interesting immunology.

Biology for AP ® Courses

Biology for AP ® Courses PDF

Author: Julianne Zedalis

Publisher:

Published: 2017-10-16

Total Pages: 1923

ISBN-13: 9781947172401

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Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.