Viral Hepatitis: Chronic Hepatitis C

Viral Hepatitis: Chronic Hepatitis C PDF

Author: Resat Ozaras

Publisher: Springer

Published: 2019-07-06

Total Pages: 0

ISBN-13: 9783030037567

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This book presents up-to-date, practically oriented information on major topics in chronic hepatitis C. The coverage encompasses epidemiology; diagnosis, including molecular methods; treatment and challenges; and the management of co-infections. Readers will find guidance on pretherapeutic evaluation with respect to disease severity and extrahepatic manifestations. Resistance to antiviral treatment and its management are discussed, and the nature of optimal follow-up is addressed in detail. Treatment of HCV/HIV co-infection is considered separately, and the approach in special patient populations is thoroughly examined. Chronic Hepatitis C will be of high value for general practitioners and specialists in gastroenterology, infectious diseases, and internal medicine. It will be international in scope in terms of both authorship and appeal.

Eliminating the Public Health Problem of Hepatitis B and C in the United States

Eliminating the Public Health Problem of Hepatitis B and C in the United States PDF

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2016-06-01

Total Pages: 187

ISBN-13: 0309438020

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Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the first of two, examines the feasibility of hepatitis B and C elimination in the United States and identifies critical success factors. The phase two report will outline a strategy for meeting the elimination goals discussed in this report.

Hepatitis C Virus: From Molecular Virology to Antiviral Therapy

Hepatitis C Virus: From Molecular Virology to Antiviral Therapy PDF

Author: Ralf Bartenschlager

Publisher: Springer Science & Business Media

Published: 2013-03-12

Total Pages: 353

ISBN-13: 3642273408

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Hepatitis C virus (HCV), a major causative agent of chronic liver disease, is spread throughout the world and around 170 million people are persistently infected. In this volume, world-leading experts in the field of HCV research have compiled the most recent scientific advances to provide a comprehensive and very timely overview of the various facets of HCV. The book starts with a discussion of the possible origin of HCV and its spread among the human population. The focus of the subsequent chapters is on available cell culture and in vivo models before shifting to the molecular and cellular principles underlying the viral replication cycle. These chapters are complemented by insightful descriptions of the innate and adaptive immune responses to HCV as well as the virus-associated pathogenesis. Finally, the development of antiviral therapies, which is closely linked with progress in basic research, and the implementation of those therapies into present and future daily clinical practice are highlighted.

Guidelines on Hepatitis B and C Testing

Guidelines on Hepatitis B and C Testing PDF

Author: World Health Organization

Publisher: World Health Organization

Published: 2017

Total Pages: 0

ISBN-13: 9789241549981

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Testing and diagnosis of hepatitis B (HBV) and C (HCV) infection is the gateway for access to both prevention and treatment services, and is a crucial component of an effective response to the hepatitis epidemic. Early identification of persons with chronic HBV or HCV infection enables them to receive the necessary care and treatment to prevent or delay progression of liver disease. Testing also provides an opportunity to link people to interventions to reduce transmission, through counselling on risk behaviors and provision of prevention commodities (such as sterile needles and syringes) and hepatitis B vaccination. These are the first WHO guidelines on testing for chronic HBV and HCV infection and complement published guidance by WHO on the prevention, care and treatment of chronic hepatitis C and hepatitis B infection. These guidelines outline the public health approach to strengthening and expanding current testing practices for HBV and HCV, and are intended for use across age groups and populations.

Hepatitis C Virus I

Hepatitis C Virus I PDF

Author: Tatsuo Miyamura

Publisher: Springer

Published: 2016-11-08

Total Pages: 0

ISBN-13: 9784431560968

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This volume is composed of chapters that review important fundamental aspects of HCV biology and disease pathogenesis including, for example, the discovery and identification of the HCV genome, early virus-cell interactions including identification of various cellular receptors, HCV gene expression studied using the HCV replicon system, identification and characterization of HCV structural- and non-structural HCV proteins, HCV replication in cultured cells, and host factors involved in viral replication. This volume also contains chapters dealing with immunity to HCV infection and pathogenesis. This is particularly important in understanding hepatitis C because HCV infection alone is not cell lytic. Mechanisms underlying the persistent nature of HCV infection are also discussed in these chapters. Many of the authors published articles that were listed among the “top 10 papers” published in the 24 years since HCV was discovered in 1989. Their citations are above 1,000 (Web of Science). The authors describe the background and significance of their contributions to the field in the context of findings from other research groups.

Hepatitis and Liver Cancer

Hepatitis and Liver Cancer PDF

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2010-05-23

Total Pages: 252

ISBN-13: 0309146283

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The global epidemic of hepatitis B and C is a serious public health problem. Hepatitis B and C are the major causes of chronic liver disease and liver cancer in the world. In the next 10 years, 150,000 people in the United States will die from liver disease or liver cancer associated with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infections. Today, between 800,000 and 1.4 million people in the United States have chronic hepatitis B and between 2.7 and 3.9 million have chronic hepatitis C. People most at risk for hepatitis B and C often are the least likely to have access to medical services. Reducing the rates of illness and death associated with these diseases will require greater awareness and knowledge among health care workers, improved identification of at-risk people, and improved access to medical care. Hepatitis B is a vaccine-preventable disease. Although federal public health officials recommend that all newborns, children, and at-risk adults receive the vaccine, about 46,000 new acute cases of the HBV infection emerge each year, including 1,000 in infants who acquire the infection during birth from their HBV-positive mothers. Unfortunately, there is no vaccine for hepatitis C, which is transmitted by direct exposure to infectious blood. Hepatitis and Liver Cancer identifies missed opportunities related to the prevention and control of HBV and HCV infections. The book presents ways to reduce the numbers of new HBV and HCV infections and the morbidity and mortality related to chronic viral hepatitis. It identifies priorities for research, policy, and action geared toward federal, state, and local public health officials, stakeholder, and advocacy groups and professional organizations.

The Hepatitis C Handbook

The Hepatitis C Handbook PDF

Author: Matthew Dolan

Publisher:

Published: 1999

Total Pages: 473

ISBN-13: 9781556433139

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This definitive guide explains the symptoms and treatments of Hepatitis C and how to cope with the disease and features extensive sections on herbs, vitamins, and nutritional supplements.

My Mom Has Hepatitis C

My Mom Has Hepatitis C PDF

Author: Hedy Weinberg

Publisher: Hatherleigh Press

Published: 2000

Total Pages: 32

ISBN-13: 9781578260751

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Jake and Celia worry when their mom tells them that the Hepatitis C virus causes her to get tired, but soon adjust and find out how medicine and liver transplants help people get well.

Living with Hepatitis C, Fifth Edition

Living with Hepatitis C, Fifth Edition PDF

Author: Gregory T. Everson

Publisher: Hatherleigh Press

Published: 2009-09-29

Total Pages: 272

ISBN-13: 1578263506

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The Most Trusted Resource and Reference for Millions of Americans Living with Hepatitis C was the first book to explain in everyday language the causes of this disease, its major and minor symptoms, and all of the latest treatments available. Researchers have continued to make dramatic strides in helping the millions of Americans who suffer from Hepatitis C since the book's first publication, and each new edition has kept up with the most recent findings. The latest revised Living With Hepatitis C, Fifth Edition includes cutting-edge information on: * New treatments including pegylated and consensus interferons * Living-donor transplants * Co-infections with Hepatitis B and HIV/AIDS * Promising new clinical trials of protease and polymerase inhibitors * New maintenance therapies, an expanded and updated resource section, ways to avoid infection, and much more Living with Hepatitis C, Fifth Edition is still the "gold standard" resource and reference for those who must endure this disease. It offers guidance and answers for those infected by the virus--and for their spouses, families, and friends.