Handbook of Tumor Syndromes

Handbook of Tumor Syndromes PDF

Author: Dongyou Liu

Publisher: CRC Press

Published: 2020-05-08

Total Pages: 1446

ISBN-13: 1351187414

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Tumors/cancers are characterized by uncontrolled growths of abnormal cells that extend beyond their usual boundaries and disrupt the normal functions of affected organs and systems. While about 75%–80% of tumors/cancers arise sporadically without a family connection, 20%–25% appear to be familial (including 10%–15% nonhereditary familial tumors [or familial tumors] and 5%–10% hereditary familial tumors [or hereditary tumors]). As nonhereditary and hereditary familial tumors often show both tumor-related and non-tumor-related (or syndromic) symptoms, they are referred to as tumor syndromes (or cancer susceptibility syndromes). In comparison with sporadic tumors/cancers, tumor syndromes (>300 described so far) tend to occur at a younger age, involve multiple organs and systems, produce multiple (often in a distinct spectrum) and bilateral lesions, form multiple hamartomatous, benign, or precursor lesions; locate in specific site(s), display unique syndromic features, and affect multiple members/generations of a family. This book provides state-of-art and authoritative coverage of nearly 100 tumor syndromes, with chapters presenting overviews of individual tumor syndromes in relation to their biology, epidemiology, pathogenesis, clinical features, diagnosis, treatment, and prognosis. Featuring contributions from oncologists, clinicians, and specialists, the book offers a reliable, comprehensive reference on tumor syndromes for scholars and students of medicine, dentistry, pharmacology, nursing, public health, and other biomedical disciplines. Key Features Reviews the biology, epidemiology, pathogenesis, and clinical features of tumor syndromes Contains up-to-date information on the diagnosis and treatment of tumor syndromes Includes expert coverage from leading oncologists and clinicians Related Titles J. R. McIntosh, Understanding Cancer: An Introduction to the Biology, Medicine, and Societal Implications of This Disease (ISBN 978-0-8153-4535-0) P. S. T. Shanmugam, Understanding Cancer Therapies (ISBN 978-1-1381-9815-9) J. M. Baehring and J. M. Piepmeier, eds., Brain Tumors: Practical Guide to Diagnosis and Treatment (ISBN 978-0-3673-9022-8) D. Liu, Tumors and Cancers: Endocrine Glands – Blood – Marrow – Lymph (ISBN 978-1-4987-2975-8) Dongyou Liu, PhD, has worked at several research and clinical laboratories in Australia and the United States for the past three decades, with a focus on molecular characterization of microbial pathogens and detection of human genetic disorders and tumors/cancers. He is the primary author of more than 50 original research and review articles in various peer-reviewed international journals, the contributor of 197 book chapters, and the editor of more than 10 books.

Principles of Clinical Cancer Genetics

Principles of Clinical Cancer Genetics PDF

Author: Daniel C. Chung

Publisher: Springer Science & Business Media

Published: 2010-07-20

Total Pages: 234

ISBN-13: 038793846X

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Advances in genetics are transforming estimates of an individual’s risk of developing cancer and approaches to prevention and management of cancer in those who may have increased susceptibility. Identifying and caring for patients with hereditary cancer syndromes and their family members present a complex clinical, scientific and social challenge. This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed. In addition, ongoing research involving genome-wide screens to identify novel modest risk-associated genetic loci are explored, along with new approaches to the application of genetic markers in guiding therapeutic options.

Handbook of Cancer Risk Assessment and Prevention

Handbook of Cancer Risk Assessment and Prevention PDF

Author: Graham A. Colditz

Publisher: Jones & Bartlett Learning

Published: 2004

Total Pages: 372

ISBN-13: 9780763718831

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Written for health care providers at all levels, this handbook covers in depth fourteen of the most common cancers in the U.S. -- providing for each a scientific summary of risk factors, a risk assessment tool for patients, and helpful hints to promote risk-reducing lifestyle changes. Additional chapters focus specifically on five key lifestyle behaviors that lower not only the risk of cancer but also the risk of other chronic diseases.Throughout its entirety, the handbook emphasizes the importance of communicating risk effectively to patients. A chapter is devoted solely to this topic, and risk information about each cancer is presented in a variety of formats. Finally, the risk assessment tools -- adaptations from the popular website Your Cancer Risk -- offer patients the option to estimate their cancer risk and receive practical, personal tips for lowering that risk.At a time when the public is surrounded by conflicting health messages, especially from the media and the Internet, the Handbook of Cancer Risk-Assessment and Prevention is an essential source for reliable, up-to-date information on cancer prevention. It delivers positive health messages and offers practical advice that health care providers can use to help patients implement strategies to prevent cancer and other chronic diseases.

Management of Genetic Syndromes

Management of Genetic Syndromes PDF

Author: Suzanne B. Cassidy

Publisher: John Wiley & Sons

Published: 2011-09-20

Total Pages: 1678

ISBN-13: 1118210670

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The bestselling guide to the medical management of common genetic syndromes —now fully revised and expanded A review in the American Journal of Medical Genetics heralded the first edition of Management of Genetic Syndromes as an "unparalleled collection of knowledge." Since publication of the first edition, improvements in the molecular diagnostic testing of genetic conditions have greatly facilitated the identification of affected individuals. This thorough revision of the critically acclaimed bestseller offers original insights into the medical management of sixty common genetic syndromes seen in children and adults, and incorporates new research findings and the latest advances in diagnosis and treatment of these disorders. Expanded to cover five new syndromes, this comprehensive new edition also features updates of chapters from the previous editions. Each chapter is written by an expert with extensive direct professional experience with that disorder and incorporates thoroughly updated material on new genetic findings, consensus diagnostic criteria, and management strategies. Edited by two of the field's most highly esteemed experts, this landmark volume provides: A precise reference of the physical manifestations of common genetic syndromes, clearly written for professionals and families Extensive updates, particularly in sections on diagnostic criteria and diagnostic testing, pathogenesis, and management A tried-and-tested, user-friendly format, with each chapter including information on incidence, etiology and pathogenesis, diagnostic criteria and testing, and differential diagnosis Up-to-date and well-written summaries of the manifestations followed by comprehensive management guidelines, with specific advice on evaluation and treatment for each system affected, including references to original studies and reviews A list of family support organizations and resources for professionals and families Management of Genetic Syndromes, Third Edition is a premier source to guide family physicians, pediatricians, internists, medical geneticists, and genetic counselors in the clinical evaluation and treatment of syndromes. It is also the reference of choice for ancillary health professionals, educators, and families of affected individuals looking to understand appropriate guidelines for the management of these disorders. From a review of the first edition: "An unparalleled collection of knowledge . . . unique, offering a gold mine of information." —American Journal of Medical Genetics

Handbook of Musculoskeletal Tumors

Handbook of Musculoskeletal Tumors PDF

Author: Matthew T. Wallace

Publisher: Slack

Published: 2020

Total Pages: 316

ISBN-13: 9781630916350

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A quick-reference handbook with more than 100 figures, charts, and images, Handbook of Musculoskeletal Tumors provides a wide-ranging overview of musculoskeletal tumors for the practicing clinician. From a pathological fracture in the emergency department to a soft tissue tumor in the clinic, musculoskeletal tumors present in clinical practice yet receive minimal exposure in training. Edited by Drs. Matthew T. Wallace and Frank J. Frassica, Handbook of Musculoskeletal Tumors provides readers with concise recommendations for their encounters with diseases including: Latent bone lesions and active and aggressive benign bone lesions Osteosarcoma, Ewing sarcoma, and primary lymphoma of bone Myeloma and metastatic bone disease, chondrosarcoma, osteochondroma, multiple hereditary exostoses, Ollier disease, and Mafucci syndrome Benign soft tissue tumors, including lipomatous tumors, nerve sheath tumors, and myxoid, fibrous, and vascular lesions Soft tissue sarcomas, including undifferentiated pleomorphic sarcoma, liposarcomas, synovial sarcoma, rhabdomyosarcoma, and epithelioid sarcoma Anatomic-specific considerations, including intra-articular lesions and hand, foot, and spine tumors Written for primary care providers, practicing orthopedists and surgeons, residents and students in training, physician assistants, and nurses and nurse practitioners, Handbook of Musculoskeletal Tumors is a practical guide to help practitioners recognize and diagnose suspicious lesions, order appropriate testing, and facilitate prompt referrals to trained musculoskeletal oncologists when appropriate for additional management. Instructors in educational settings can visitwww.efacultylounge.com for additional materials to be used for teaching in the classroom.

Handbook of Cancer Treatment-Related Symptoms and Toxicities

Handbook of Cancer Treatment-Related Symptoms and Toxicities PDF

Author: Vamsidhar Velcheti

Publisher: Elsevier Health Sciences

Published: 2021-01-28

Total Pages: 355

ISBN-13: 032367299X

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Early recognition and management of adverse effects of cancer treatments are essential for optimal care of patients with cancer, and drastically different approaches are required for different physiologic reactions. Handbook of Cancer Treatment-Related Symptoms and Toxicities is a focused, one-stop resource that enables clinicians to quickly find up-to-date, reliable information needed at the point of care. The high-yield approach prioritizes the most common toxicities associated with cancer treatment, and concise, templated chapters offer fast access to information needed in day-to-day practice. Presents a user-friendly overview of cancer treatment-related symptoms and toxicities management in a practical, easy-to-use format, allowing you to quickly find information in one convenient, concise resource. Covers systemic and radiation therapies, including chemotherapy, immunotherapy, targeted therapies, and radiation therapy, detailing symptoms of each toxicity to confirm your diagnosis. Overviews pharmacologic and non-pharmacologic approaches to symptom management. Offers recommendations for mitigating toxicities in high-risk patients. Discusses key topics such as management of infusion reactions, when the need for biopsy is warranted, and the unique challenges posed by novel immunotherapies.

Soft Tissue and Bone Tumours

Soft Tissue and Bone Tumours PDF

Author: WHO Classification of Tumours Editorial Board

Publisher: WHO Classification of Tumours

Published: 2020

Total Pages: 0

ISBN-13: 9789283245025

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PLEASE NOTE: Text has been accidentally deleted from page 54 of this book. Please refer to the corrigenda (PDF file) posted on the Stylus Publishing web site or email [email protected] for an updated, printable page. ****When not purchasing directly from the official sales agents of the WHO, especially at online bookshops, please note that there have been issues with counterfeited copies. Buy only from known sellers and if there are quality issues, please contact the seller for a refund.***** Soft Tissue and Bone Tumours is the third volume in the 5th edition of the WHO series on the classification of human tumours. This series (also known as the WHO Blue Books) is regarded as the gold standard for the diagnosis of tumours and comprises a unique synthesis of histopathological diagnosis with digital and molecular pathology. These authoritative and concise reference books provide indispensable international standards for anyone involved in the care of patients with cancer or in cancer research, underpinning individual patient treatment as well as research into all aspects of cancer causation, prevention, therapy, and education. This volume will be of particular interest to pathologists, oncologists, surgeons, and epidemiologists who manage or research soft tissue and bone tumours. Sections are included on all recognized neoplasms of the soft tissue and bone, as well as on genetic tumour syndromes affecting these sites. Since the previous edition, there have been changes based on recent molecular and genetic information, with impact on clinical practice.