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Handbook of Toxicology, Second Edition

Author: Michael J. Derelanko

Publisher: CRC Press

Published: 2001-08-29

Total Pages: 1448

ISBN-13: 9780849303708

LOCATE FREQUENTLY USED INFORMATION EASILY AND QUICKLY Working in the laboratory or office, you use a diverse assortment of basic information to design, conduct, and interpret toxicology studies and to perform risk assessments. The Second Edition of the best-selling Handbook of Toxicology gives you the information you need in a single reference source. NEW IN THIS EDITION: Expanded coverage of inhalation toxicology, neurotoxicology, and histopathology Additional regulatory chapters dealing with pesticides, medical devices, consumer products, and world-wide notification of new chemicals Areas of toxicology missing from the first edition such as ecotoxicology and in vitro toxicology A chapter providing extensive overview of the toxicology of metals Two chapters on basic male and female endocrinology and related toxicology Information on differences in physiological and biochemical parameters between children and adults References to Web site sources of valuable information Over 200 new tables and figures THE SINGLE SOURCE FOR THE INFORMATION YOU USE MOST FREQUENTLY Updated and expanded, this unique book includes practical reference information useful to toxicologists in the chemical and pharmaceutical industries, contract laboratories, regulatory agencies, and academia. To help you find information quickly and easily, data is arranged by toxicology subspecialty and each chapter begins with a detailed listing of information presented. Containing over 700 tables and figures, Handbook of Toxicology, Second Edition gives you a single source for the information you use most often.

Toxicology Handbook

Author: Lindsay Murray

Publisher: Elsevier Australia

Published: 2011

Total Pages: 543

ISBN-13: 0729539393

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The Toxicology Handbook 2e is a practical, didactic guide to the approach, assessment and management of poisoned patients. It has been written for hospital-based doctors at all levels and describes the risk assessment-based approach pioneered by the principal authors. the concise layout enables the reader to quickly locate information in a poisoning emergency. the book also features locally relevant information on bites, stings and envenoming. This book will also be useful for ambulance service paramedics and pharmacists.

A Comprehensive Guide to Toxicology in Nonclinical Drug Development

Author: Ali S. Faqi

Publisher: Elsevier

Published: 2024-02-11

Total Pages: 1074

ISBN-13: 0323984622

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A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Third Edition is a valuable reference providing a complete understanding of all aspects of nonclinical toxicology in pharmaceutical research. This updated edition has been expanded and re-developed covering a wide-range of toxicological issues in small molecules and biologics. Topics include ADME in drug discovery, pharmacokinetics, toxicokinetics, formulations, and genetic toxicology testing. The book has been thoroughly updated throughout to reflect the latest scientific advances and includes new information on antiviral drugs, anti-diabetic drugs, immunotherapy, and a discussion on post-pandemic drug development challenges and opportunities. This is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. Provides updated, unique content not covered in one comprehensive resource, including chapters on stem cells, antiviral drugs, anti-diabetic drugs, and immunotherapy Includes the latest international guidelines for nonclinical toxicology in both small and large molecules Incorporates practical examples in order to illustrate day-to-day activities and expectations associated with working in nonclinical toxicology

Clinical Toxicology

Author: Frank A. Barile

Publisher: CRC Press

Published: 2010-02-15

Total Pages: 484

ISBN-13: 142009226X

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Examining the complex interactions associated with clinical toxicological events and chemical exposure of drug administration, this updated and revised Second Edition functions as a stand-alone text or reference of clinical toxicology for professionals, students of toxicology and pharmacy, as well as forensic toxicologists, occupational healthcare

Handbook of Ecotoxicology

Author: David J. Hoffman

Publisher: CRC Press

Published: 2002-11-13

Total Pages: 1316

ISBN-13: 142003250X

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Handbook of Ecotoxicology, Second Edition focuses on toxic substances and how they affect ecosystems worldwide. It presents methods for quantifying and measuring ecotoxicological effects in the field and in the lab, as well as methods for estimating, predicting, and modeling in ecotoxicology studies. Completely revised and updated with 18 new chapt

The Toxicologist's Pocket Handbook, Second Edition

Author: Michael J. Derelanko

Publisher: CRC Press

Published: 2017-11-10

Total Pages:

ISBN-13: 9781138473607

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Originally published to provide quick and portable access to the most frequently needed information in the original bestselling CRC Handbook of Toxicology, this new pocketbook is designed to serve the same purpose for the recently revised and expanded Handbook. It continues to provide the most frequently used toxicological reference material in a convenient pocket-sized format. Several sections have been expanded to offer important new information and meet current and emerging areas of concern. A great number of new tables have been added and a few less useful ones eliminated. It also includes a much more timely and reformatted glossary.

Handbook on the Toxicology of Metals: Volume II: Specific Metals

Author: Gunnar F. Nordberg

Publisher: Academic Press

Published: 2021-12-01

Total Pages: 1054

ISBN-13: 0128231386

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Handbook on the Toxicology of Metals, Volume II: Specific Metals, Fifth Edition provides complete coverage of 38 individual metals and their compounds. This volume is the second volume of a two-volume work which emphasizes toxic effects in humans, along with discussions on the toxic effects of animals and biological systems in vitro when relevant. The book has been systematically updated with the latest studies and advances in technology. As a multidisciplinary resource that integrates both human and environmental toxicology, the book is a comprehensive and valuable reference for toxicologists, physicians, pharmacologists, and environmental scientists in the fields of environmental, occupational and public health. Contains peer-reviewed chapters that deal with the effects of metallic elements and their compounds on biological systems with a focus on human health effects Includes information on sources, transport, and the transformation of metals in the environment Provides critical information on the properties, use, biological monitoring, dose-response relationships, diagnosis, treatment, and prevention of 38 metallic elements and their compounds

Handbook of Small Animal Toxicology and Poisonings

Author: Roger W. Gfeller

Publisher:

Published: 2004

Total Pages: 0

ISBN-13: 9780323012461

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This time-saving, pocket-size guide offers a thorough understanding of toxicology that is essential to diagnosing and treating the complex problems resulting from toxin ingestion, a leading cause of morbidity and mortality in animals. The 2nd edition covers patient assessment and treatment techniques, as well as information on over 100 categories of toxic agents. Discussions of each agent include its uses, mechanism, pathophysiology, clinical signs, diagnosis, common products containing the agent, and acute and long-term treatment. A new avian section makes this edition even more comprehensive and clinically useful. Over 1,000 toxic agents are discussed, offering a thorough presentation of toxicology relevant to veterinary practice. An easy-to-use alphabetical organization with section tabs for quick reference makes information easy to locate in any setting. Detailed diagnostic and treatment information is presented in an appealing, visually accessible approach. A greater emphasis on the ingestion of human medications addresses this common concern in detail. Additional plant and chemical toxins are discussed to highlight potential poisonings seen in veterinary practice. A new avian section focuses on specific considerations for treating birds. Redesigned icons draw attention to important points and sections to improve the text's readability. A four-page, full-color insert features approximately 24 color photographs of poisonous plants for quick identification. All content has been reviewed by board-certified toxicologists to ensure that it is up-to-date and accurate. A second color throughout makes the icons more readable, the design more inviting, and critical information more accessible.

Animal Clinical Chemistry

Author: G.O. Evans

Publisher: CRC Press

Published: 1996-04-29

Total Pages: 230

ISBN-13: 0748403507

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By presenting background information on the selection and application of biochemical tests in safety assessment studies, this text seeks to provide a basis for improving the knowledge required to interpret data from toxicological studies. In addition to chapters which discuss the assessment of specific organ toxicity (such as the liver, kidney and thyroid), the book also covers pre-analytical variables, regulatory requirements and statistical approaches, and highlights some of the major differences between man and different laboratory animals. The editor and contributor are all members of the Animal Clinical Chemistry Association, a group formed to advance the science of animal clinical chemistry in safety evaluation, toxicology and veterinary science.

Chemical Warfare Agents

Author: Timothy T. Marrs

Publisher: John Wiley & Sons

Published: 2007-04-04

Total Pages: 750

ISBN-13: 0470060026

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Chemical Warfare Agents, Second Edition has been totally revised since the successful first edition and expanded to about three times the length, with many new chapters and much more in-depth consideration of all the topics. The chapters have been written by distinguished international experts in various aspects of chemical warfare agents and edited by an experienced team to produce a clear review of the field. The book now contains a wealth of material on the mechanisms of action of the major chemical warfare agents, including the nerve agent cyclosarin, formally considered to be of secondary importance, as well as ricin and abrin. Chemical Warfare Agents, Second Edition discusses the physico-chemical properties of chemical warfare agents, their dispersion and fate in the environment, their toxicology and management of their effects on humans, decontamination and protective equipment. New chapters cover the experience gained after the use of sarin to attack travellers on the Tokyo subway and how to deal with the outcome of the deployment of riot control agents such as CS gas. This book provides a comprehensive review of chemical warfare agents, assessing all available evidence regarding the medical, technical and legal aspects of their use. It is an invaluable reference work for physicians, public health planners, regulators and any other professionals involved in this field. Review of the First Edition: "What more appropriate time for a title of this scope than in the post 9/11 era? ...a timely, scholarly, and well-written volume which offers much information of immense current and...future benefit." —VETERINARY AND HUMAN TOXICOLOGY