-PDF Download- Handbook Of Analytical Therapeutic Drug Monitoring And Toxicology 1996 EBOOK

Handbook of Analytical Therapeutic Drug Monitoring and Toxicology (1996)

Author: Steven H.Y. Wong

Publisher: CRC Press

Published: 2017-11-22

Total Pages: 367

ISBN-13: 1351364286

Adapting modern advances in analytical techniques to daily laboratory practices challenges many toxicologists, clinical laboratories, and pharmaceutical scientists. The Handbook of Analytical Therapeutic Drug Monitoring and Toxicology helps you keep abreast of the innovative changes that can make your laboratory - and the studies undertaken in it - a success. This volume simplifies your search for appropriate techniques, describes recent contributions from leading investigators, and provides valuable evaluations and advice.

Handbook of Drug Monitoring Methods

Author: Amitava Dasgupta

Publisher: Springer Science & Business Media

Published: 2007-10-05

Total Pages: 441

ISBN-13: 1597450316

DOWNLOAD EBOOK →

Written in a handbook style with specific methods and tips on eliminating false positive and false negative results, this book is a practical guide to the detailed mechanisms of such occurrences.

Analytical Methods for Therapeutic Drug Monitoring and Toxicology

Author: Q. Alan Xu

Publisher: John Wiley & Sons

Published: 2011-04-12

Total Pages: 913

ISBN-13: 0470922796

DOWNLOAD EBOOK →

This book is a compilation of summarized analytical methods designed to serve the needs of pharmacologists, toxicologists, and other allied health professionals involved the development, use, or monitoring of pharmaceuticals. The summaries are structured monographs on 511 different drug entities detailing 964 different analytical methods, providing the reader with a thorough description of method validation. These analytical methods include not only high performance liquid chromatography (HPLC), but also gas chromatography (GC), immunoassay, electrophoresis, ultra performance liquid chromatography (UPLC) coupled with UV (UPLC-UV) detection and mass spectrometry (UPLC-MS/MS). With more detailed and complete summaries than sketchy and abbreviated formats used in the other books, this book provides a thorough description of method validation and results, as well as the operating parameters.

Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology

Author: Seth Kwabena Amponsah

Publisher: Springer Nature

Published: 2022-10-25

Total Pages: 384

ISBN-13: 3031123980

DOWNLOAD EBOOK →

This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges

Methods of Therapeutic Drug Monitoring Including Pharmacogenetics

Author: Georg Hempel

Publisher: Elsevier

Published: 2019-10-17

Total Pages: 380

ISBN-13: 0444640673

DOWNLOAD EBOOK →

Methods of Therapeutic Drug Monitoring Including Pharmacogenetics, Second Edition, Volume Seven in the Handbook of Analytical Separations series, covers all aspects of drug monitoring, including laboratory work, pharmacokinetic analysis and clinical aspects, thus enabling readers from different fields to understand the whole process of therapeutic drug monitoring and how to avoid common pitfalls. The book contains analytical techniques for the quantification of drugs, along with pharmacogenetic and pharmacogenomic methods. Also included are updates on sample preparation, including dried blood spot technology and microextraction methods. In addition, the book includes new drugs, such as tyrosine kinase inhibitors and the monitoring of immunosuppressant drugs. Presents a unique, interdisciplinary approach that appeals to a wide range of users Written by authors from international labs, providing a global perspective that can be applied in various regulatory environments Features additional therapeutic drugs to reflect the rising number of immunocompromised patients Includes a new mass spectroscopic methods chapter to capture the frequent use in TDM and the improved availability of LC-MS across laboratories

Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography

Author: Steven H.Y. Wong

Publisher: Routledge

Published: 2017-09-19

Total Pages: 521

ISBN-13: 135140847X

DOWNLOAD EBOOK →

This important, new reference provides the first , up-to-date, and comprehensive treatmentof the various liquid chromatography (LC) instrumentation for Therapeutic DrugMonitoring (TDM) and toxicology drug assays and reviews the clinical pharmacologyof major classes of drugs and their LC analyses.Written by authoritative contributors who bring many years of personal laboratory/clinical experience to the book, this interdisciplinary work : presents the principlesof TDM, sampling techniques, and various instrumentation topics, including computerinterfacing, mass spectrometry, fluorescence , electrochemical detection, and bloodcollection devices . .. examines six primary classes of drugs, complete with recommendedLC procedures and emphasizing recently introduced drugs and their LC analyses. .. and documents medicolegal guidelines and laboratory management considerations,providing a contemporary assessment of today's laboratory needs.The only practical, current guide available on the subject, Therapeutic Drug Monitoringand Toxicology by Li([uid Chromatography belongs in the personal libraries of clinicaland analytical chemists and biochemists, clinical pharmacologists, clinical toxicologists,clinical pathologists, immunologists, liquid chromatographers, mass spectroscopists, laboratorydirectors, laboratory instrument manufacturers , and medical technologists. Thebook is also vital supplementary reading for advanced undergraduate and graduate-levelclinical chemistry, toxicology, clinical pathology, and liquid chromatography course.

Forensic Science

Author:

Publisher: Elsevier

Published: 2000-11-17

Total Pages: 775

ISBN-13: 0080531857

DOWNLOAD EBOOK →

Forensic Science

Separation Techniques in Clinical Chemistry

Author: Hassan Y. Aboul-Enein

Publisher: CRC Press

Published: 2003-05-28

Total Pages: 548

ISBN-13: 9780203911105

DOWNLOAD EBOOK →

This reference examines innovations in separation science for improved sensitivity and cost-efficiency, increased speed, higher sample throughput and lower solvent consumption in the assessment, evaluation, and validation of emerging drug compounds. It investigates breakthroughs in sample pretreatment, HPLC, mass spectrometry, capillary electrophor

Antiepileptic Drugs

Author: M.J. Eadie

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 658

ISBN-13: 3642600727

DOWNLOAD EBOOK →

In 1985, volume 74 of the Springer-Verlag Handbook of Experimental Phar macology, under the editorship of H. -H. Frey and D. Janz, appeared. In this volume the then available data on the topic of antiepileptic drugs were col lated and analysed. Over the intervening years knowledge in this area has grown progressively. More new antiepileptic drugs than the total number of agents that were in common use 15 years ago have in the interval either come on to the market or are about to do so. As well, further agents are at a fairly advanced stage of development, whilst the already established drugs have by and large held their places in clinical practice. Knowledge of epileptogenesis has advanced considerably. The mechanisms of action of antiepileptic drugs at the molecular level and in various animal models of epileptic seizures and of the epileptic state are much better understood than they were previously. As well, more information is available concerning the natural history of human epilepsy, and this knowledge is important in making optimal use of the various agents that are now available. Therefore, it has seemed appropriate at this stage in the evolution of knowledge to produce a second volume dealing with Antiepileptic Drugs in the Handbook of Experimental Pharmacology series.

Analytical and Practical Aspects of Drug Testing in Hair

Author: Pascal Kintz

Publisher: CRC Press

Published: 2006-08-30

Total Pages: 382

ISBN-13: 1420006193

DOWNLOAD EBOOK →

Many advances have been made since the publication of Drug Testing in Hair. The mid-1990s witnessed the progress in cannabis detection while the late 1990s focused on benzodiazepines detection and the applications in doping control. In more recent years, toxicologists centered on the detection in hair of a single exposure and the related applicatio