A Dominant Character: How J. B. S. Haldane Transformed Genetics, Became a Communist, and Risked His Neck for Science

A Dominant Character: How J. B. S. Haldane Transformed Genetics, Became a Communist, and Risked His Neck for Science PDF

Author: Samanth Subramanian

Publisher: W. W. Norton & Company

Published: 2020-07-28

Total Pages: 475

ISBN-13: 0393634256

DOWNLOAD EBOOK →

One of the Wall Street Journal's 10 Best Books of 2020 One of the New York Times's 100 Notable Books of 2020 A biography of J. B. S. Haldane, the brilliant and eccentric British scientist whose innovative predictions inspired Aldous Huxley’s Brave New World. J. B. S. Haldane’s life was rich and strange, never short on genius or drama—from his boyhood apprenticeship to his scientist father, who first instilled in him a devotion to the scientific method; to his time in the trenches during the First World War, where he wrote his first scientific paper; to his numerous experiments on himself, including inhaling dangerous levels of carbon dioxide and drinking hydrochloric acid; to his clandestine research for the British Admiralty during the Second World War. He is best remembered as a geneticist who revolutionized our understanding of evolution, but his peers hailed him as a polymath. One student called him “the last man who might know all there was to be known.” He foresaw in vitro fertilization, peak oil, and the hydrogen fuel cell, and his contributions ranged over physiology, genetics, evolutionary biology, mathematics, and biostatistics. He was also a staunch Communist, which led him to Spain during the Civil War and sparked suspicions that he was spying for the Soviets. He wrote copiously on science and politics in newspapers and magazines, and he gave speeches in town halls and on the radio—all of which made him, in his day, as famous in Britain as Einstein. It is the duty of scientists to think politically, Haldane believed, and he sought not simply to tell his readers what to think but to show them how to think. Beautifully written and richly detailed, Samanth Subramanian’s A Dominant Character recounts Haldane’s boisterous life and examines the questions he raised about the intersections of genetics and politics—questions that resonate even more urgently today.

Enzymes

Enzymes PDF

Author: John Burdon Sanderson Haldane

Publisher: MIT Press (MA)

Published: 1965

Total Pages: 264

ISBN-13:

DOWNLOAD EBOOK →

Reasonable Faith

Reasonable Faith PDF

Author: John Haldane

Publisher: Routledge

Published: 2010-02-25

Total Pages: 447

ISBN-13: 1135165491

DOWNLOAD EBOOK →

In this awaited follow up to his book Faithful Reason, the well-known philosopher and Catholic thinker John Haldane brings his unrivalled insight to bear on questions of the existence of God and the nature and destiny of the human soul. His arguments weave elements drawn from philosophy of mind, epistemology and aesthetics, together with recurrent features of human experience to create a structure that simultaneously frames and supports ideas such as that the cosmos is a creation, human beings transcend their material composition, and that human fulfilment lies beyond death. As in many of his other writings this volume blends themes from Aquinas with insights drawn from analytical philosophy and further establishes John Haldane as the leading 'analytical thomist'.

Haldane, Mayr, and Beanbag Genetics

Haldane, Mayr, and Beanbag Genetics PDF

Author: Krishna Dronamraju

Publisher: Oxford University Press

Published: 2011-01-07

Total Pages: 293

ISBN-13: 0199813345

DOWNLOAD EBOOK →

Haldane, Mayr, and Beanbag Genetics presents a summary of the classic exchange between two great biologists - J.B.S. Haldane and Ernst Mayr - regarding the value of the contributions of the mathematical school represented by J.B.S. Haldane, R.A. Fisher and S. Wright to the theory of evolution. Their pioneering contributions from 1918 to the 1960s dominated and shaped the field of population genetics, unique in the annals of science. In 1959, Mayr questioned what he regarded as the beanbag genetic approach of these pioneers to evolutionary theory, "an input or output of genes, as the adding of certain beans to a beanbag and the withdrawing of others." In 1964, Mayr's contention was refuted by Haldane in a remarkably witty, vigorous and pungent essay, "A defense of beanbag genetics" which compared the mathematical theory to a scaffolding within which a reasonably secure theory expressible in words may be built up. Correspondence between Haldane and Mayr is included. Beanbag genetics has come a long way since 1964. Mayr's (1959) critique of simple uncomplicated population genetics is no longer valid. Population genetics today includes much more than Mayr's beanbag genetics. Population genetics models now include multiple factors, linkage, dominance and epistasis. These may be regarded as the advanced beanbag models. Furthermore, population genetics and developmental genetics have become interdependent. Contemporary beanbag genetics includes molecular clocks, nucleotide diversity, coalescence and DNA-based phylogenetic trees, along with the four major holdovers from classical genetics, mutation, selection, migration and random drift. Molecular genetics has made it possible to study evolution rates at the nucleotide level. It is also possible today to compare DNA similarities and divergence in diverse species of animals and plants, which were not previously crossable.

Haldane

Haldane PDF

Author: John Campbell

Publisher: McGill-Queen's Press - MQUP

Published: 2020-07-16

Total Pages: 608

ISBN-13: 0228002338

DOWNLOAD EBOOK →

Can you name the creator of the Territorial Army, the British Expeditionary Force, the Imperial General Staff, and the Officers' Training Corps? The man who laid the foundation stones of MI5, MI6, the RAF, the LSE, Imperial College, the "redbrick" universities, and the Medical Research Council? This book restores Richard Burdon Haldane to his rightful place among the great men of British and Canadian history. Serving as war minister in the 1905 Liberal British government, his groundbreaking proposals on defence, education, and government structure were astonishingly ahead of his time – the very building blocks of modern Britain. Even the Canadian Constitution, as now interpreted, is unthinkable without Haldane. His ubiquitous networks ranged from Wilde to Einstein, Churchill to Carnegie, king to kaiser; his polymathic interests enabled pioneering cross-party, cross-sector cooperation. Yet in 1915 he was ejected from the Lord Chancellorship, unjustly vilified by an ignorant press campaign as a German sympathizer. John Campbell charts these ups and downs, reveals the intensely personal side of Haldane through previously unpublished love letters, and shows his enormous relevance in our search for just societies and states today. Amidst political and national instability, it is surely now right to reinstate Haldane as an outstanding example of true statesmanship.

Popularizing Science

Popularizing Science PDF

Author: Krishna R. Dronamraju

Publisher: Oxford University Press

Published: 2017

Total Pages: 385

ISBN-13: 0199333920

DOWNLOAD EBOOK →

J.B.S. Haldane (1892-1964) is widely appreciated as one of the greatest and most influential British scientists of the 20th century, making significant contributions to genetics, physiology, biochemistry, biometry, cosmology, and other sciences. More remarkable, then, is the fact that Haldane had no formal qualification in science. He made frequent appearances in the media, making pronouncements on a variety of poignant topics including mining disasters, meteorites, politics, and the economy, and was a popular scientific essay writer. Haldane also was famed for conducting painful experiments on himself, including several instances in which he permanently injured himself. A staunch Marxist and convert to Hinduism, Haldane lived a diverse, lively and interesting life that is still revered by today's science community. A biography of Haldane has not been attempted since 1968, and that book provided an incomplete account of the man's scientific achievement. "The Life and Works of J.B.S. Haldane" serves to fix this glaring omission, providing a complete biographical sketch written by Krishna Dronamraju, one of the last living men to have worked personally with Haldane. A new genre of biographies of 20th-century scientists has come into being, and thus far works have been written about men like Einstein, Oppenheimer, Bernal, Galton, and many more; the inclusion of Haldane within this genre is an absolute necessity. Dronamraju evaluates Haldane's social and political background, as well as his scientific creativity and accomplishments. Haldane embodies a generation of intellectuals who believed and promoted knowledge for its own sake, and that spirit of scientific curiosity and passion is captured in this biography.

Selected Genetic Papers of J.B.S. Haldane (Routledge Revivals)

Selected Genetic Papers of J.B.S. Haldane (Routledge Revivals) PDF

Author: Krishna R. Dronamraju

Publisher: Taylor & Francis

Published: 2022-05-29

Total Pages: 565

ISBN-13: 1317667212

DOWNLOAD EBOOK →

First published in 1990, this is a compilation of several important papers that have contributed to the foundation of population genetics, evolutionary biology and human genetics. The collection includes Haldane’s first paper in genetics, which was published in 1915, reporting the first case of linkage in a mammal, and - fifty years later, in 1965 - his last paper in genetics on selection for a single pair of allelomorphs with complete replacement. Haldane's Rule, the only idea named after him, was published in 1922 and is still valid today. Other papers, which include many Haldane firsts, such as the first estimation of a human mutation rate, first human gene map, first papers in population genetics, first estimate of the probability of fixation of a new mutation, and first measurement of mutation impact on a population, leading to the "genetic load" concept, are included. The volume also includes a paper presenting an ancient logical system for interpreting scientific results.