Guinea Pig Zero

Guinea Pig Zero PDF

Author: Robert Helms

Publisher: Garrett County Press

Published: 2005-02-08

Total Pages: 270

ISBN-13: 1891053280

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From first person accounts of pharmaceutical studies gone bad to intricate medical histories, Guinea Pig Zero provides a fascinating look at the people who sell their bodies to science. While the book provides advice to present-day research subjects (by rating research clinics), the book also provides context by investigating the history and ethics behind this important, but little-known medical industry.

The Professional Guinea Pig

The Professional Guinea Pig PDF

Author: Roberto Abadie

Publisher: Duke University Press

Published: 2010-07-30

Total Pages: 199

ISBN-13: 0822393247

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The Professional Guinea Pig documents the emergence of the professional research subject in Phase I clinical trials testing the safety of drugs in development. Until the mid-1970s Phase I trials were conducted on prisoners. After that practice was outlawed, the pharmaceutical industry needed a replacement population and began to aggressively recruit healthy, paid subjects, some of whom came to depend on the income, earning their living by continuously taking part in these trials. Drawing on ethnographic research among self-identified “professional guinea pigs” in Philadelphia, Roberto Abadie examines their experiences and views on the conduct of the trials and the risks they assume by participating. Some of the research subjects he met had taken part in more than eighty Phase I trials. While the professional guinea pigs tended to believe that most clinical trials pose only a moderate health risk, Abadie contends that the hazards presented by continuous participation, such as exposure to potentially dangerous drug interactions, are discounted or ignored by research subjects in need of money. The risks to professional guinea pigs are also disregarded by the pharmaceutical industry, which has become dependent on the routine participation of experienced research subjects. Arguing that financial incentives compromise the ethical imperative for informed consent to be freely given by clinical-trials subjects, Abadie confirms the need to reform policies regulating the participation of paid subjects in Phase I clinical trials.

White Coat, Black Hat

White Coat, Black Hat PDF

Author: Carl Elliott

Publisher: Beacon Press

Published: 2011-09-13

Total Pages: 233

ISBN-13: 0807061441

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By New Yorker and Atlantic writer Carl Elliott, a readable and even funny account of the serious business of medicine. A tongue-in-cheek account of the changes that have transformed medicine into big business. Physician and medical ethicist Carl Elliott tracks the new world of commercialized medicine from start to finish, introducing the professional guinea pigs, ghostwriters, thought leaders, drug reps, public relations pros, and even medical ethicists who use medicine for (sometimes huge) financial gain. Along the way, he uncovers the cost to patients lost in a health-care universe centered around consumerism.

Captain America and the Struggle of the Superhero

Captain America and the Struggle of the Superhero PDF

Author: Robert G. Weiner

Publisher: McFarland

Published: 2009-06-08

Total Pages: 268

ISBN-13: 0786453400

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For more than 60 years, Captain America was one of Marvel Comics' flagship characters, representing truth, strength, liberty, and justice. The assassination of his alter ego, Steve Rogers, rocked the comic world, leaving numerous questions about his life and death. This book discusses topics including the representation of Nazi Germany in Captain America Comics from the 1940s to the 1960s; the creation of Captain America in light of the Jewish American experience; the relationship between Captain America and UK Marvel's Captain Britain; the groundbreaking partnership between Captain America and African American superhero the Falcon; and the attempts made to kill the character before his "real" death.

Guinea Pigs Add Up

Guinea Pigs Add Up PDF

Author: Margery Cuyler

Publisher: Walker Childrens

Published: 2010-07-01

Total Pages: 0

ISBN-13: 9780802797957

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In bouncy, appealing rhyme, young readers are introduced to a classroom with a hairy problem-guinea pigs that keep adding and adding! From one lonely guinea pig to two to five and all the way up to twenty, the kids find that having a classroom pet is more than they bargained for. Finally, each student gets to take a guinea pig home, until they are left with zero. That is, until Mr. Gilbert brings in a rabbit with a growing belly . . . ! From master storyteller Margery Cuyler and with energetic illustrations from Tracey Campbell Pearson, Guinea Pigs Add Up is perfect for budding mathematicians-or anyone with a love for unruly animals.

Guitar Zero

Guitar Zero PDF

Author: Gary Marcus

Publisher: Penguin

Published: 2012-01-19

Total Pages: 252

ISBN-13: 110155228X

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On the eve of his 40th birthday, Gary Marcus, a renowned scientist with no discernible musical talent, learns to play the guitar and investigates how anyone—of any age —can become musical. Do you have to be born musical to become musical? Do you have to start at the age of six? Using the tools of his day job as a cognitive psychologist, Gary Marcus becomes his own guinea pig as he takes up the guitar. In a powerful and incisive look at how both children and adults become musical, Guitar Zero traces Marcus’s journey, what he learned, and how anyone else can learn, too. A groundbreaking peek into the origins of music in the human brain, this musical journey is also an empowering tale of the mind’s enduring plasticity. Marcus investigates the most effective ways to train body and brain to learn to play an instrument, in a quest that takes him from Suzuki classes to guitar gods. From deliberate and efficient practicing techniques to finding the right music teacher, Marcus translates his own experience—as well as reflections from world-renowned musicians—into practical advice for anyone hoping to become musical, or to learn a new skill. Guitar Zero debunks the popular theory of an innate musical instinct while simultaneously challenging the idea that talent is only a myth. While standing the science of music on its head, Marcus brings new insight into humankind’s most basic question: what counts as a life well lived? Does one have to become the next Jimi Hendrix to make a passionate pursuit worthwhile, or can the journey itself bring the brain lasting satisfaction? For all those who have ever set out to play an instrument—or wish that they could—Guitar Zero is an inspiring and fascinating look at the pursuit of music, the mechanics of the mind, and the surprising rewards that come from following one’s dreams.

The Plutonium Files

The Plutonium Files PDF

Author: Eileen Welsome

Publisher: Delta

Published: 2010-10-20

Total Pages: 814

ISBN-13: 0307767337

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When the vast wartime factories of the Manhattan Project began producing plutonium in quantities never before seen on earth, scientists working on the top-secret bomb-building program grew apprehensive. Fearful that plutonium might cause a cancer epidemic among workers and desperate to learn more about what it could do to the human body, the Manhattan Project's medical doctors embarked upon an experiment in which eighteen unsuspecting patients in hospital wards throughout the country were secretly injected with the cancer-causing substance. Most of these patients would go to their graves without ever knowing what had been done to them. Now, in The Plutonium Files, Pulitzer Prize-winning reporter Eileen Welsome reveals for the first time the breadth of the extraordinary fifty-year cover-up surrounding the plutonium injections, as well as the deceitful nature of thousands of other experiments conducted on American citizens in the postwar years. Welsome's remarkable investigation spans the 1930s to the 1990s and draws upon hundreds of newly declassified documents and other primary sources to disclose this shadowy chapter in American history. She gives a voice to such innocents as Helen Hutchison, a young woman who entered a prenatal clinic in Nashville for a routine checkup and was instead given a radioactive "cocktail" to drink; Gordon Shattuck, one of several boys at a state school for the developmentally disabled in Massachusetts who was fed radioactive oatmeal for breakfast; and Maude Jacobs, a Cincinnati woman suffering from cancer and subjected to an experimental radiation treatment designed to help military planners learn how to win a nuclear war. Welsome also tells the stories of the scientists themselves, many of whom learned the ways of secrecy on the Manhattan Project. Among them are Stafford Warren, a grand figure whose bravado masked a cunning intelligence; Joseph Hamilton, who felt he was immune to the dangers of radiation only to suffer later from a fatal leukemia; and physician Louis Hempelmann, one of the most enthusiastic supporters of the plan to inject humans with potentially carcinogenic doses of plutonium. Hidden discussions of fifty years past are reconstructed here, wherein trusted government officials debated the ethical and legal implications of the experiments, demolishing forever the argument that these studies took place in a less enlightened era. Powered by her groundbreaking reportage and singular narrative gifts, Eileen Welsome has created a work of profound humanity as well as major historical significance. From the Hardcover edition.

Beyond Bioethics

Beyond Bioethics PDF

Author: Osagie K. Obasogie

Publisher: Univ of California Press

Published: 2018-03-09

Total Pages: 547

ISBN-13: 0520961943

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For decades, the field of bioethics has shaped the way we think about ethical problems in science, technology, and medicine. But its traditional emphasis on individual interests such as doctor-patient relationships, informed consent, and personal autonomy is minimally helpful in confronting the social and political challenges posed by new human biotechnologies such as assisted reproduction, human genetic modification, and DNA forensics. Beyond Bioethics addresses these provocative issues from an emerging standpoint that is attentive to race, gender, class, disability, privacy, and notions of democracy—a "new biopolitics." This authoritative volume provides an overview for those grappling with the profound dilemmas posed by these developments. It brings together the work of cutting-edge thinkers from diverse fields of study and public engagement, all of them committed to this new perspective grounded in social justice and public interest values.

Chasing Medical Miracles

Chasing Medical Miracles PDF

Author: Alex O'Meara

Publisher: Bloomsbury Publishing USA

Published: 2010-06-03

Total Pages: 273

ISBN-13: 0802719902

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Provides a ehind-the-scenes look at clinical trials and how the companies involved with them have becomesignificant partart of the American medical establishment.