Germfree Life And Gnotobiology

Germfree Life And Gnotobiology PDF

Author: Thomas Luckey

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 527

ISBN-13: 0323147100

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Germfree Life and Gnotobiology focuses on the theory and general aspects of germfree research and gnotobiology. Using a phylogenetic approach, the book provides a summary of germfree work in all phyla, from bacteria and viruses to protozoans and invertebrates. It characterizes germfree vertebrates based on data on morphology, biochemistry, nutrition, serology, and physiology. This book is organized into six chapters and begins with an overview of germfree life and gnotobiology, including biological isolation as the basis of germfree life, germfree conditions in nature, and the biological significance of germfree research. A section is devoted to nomenclature and terminology. The chapters on methods and nutrition are sufficiently detailed to serve as guides for experimental work. The book concludes with a chapter on exploratory research that explores the inoculation of germfree animals with known kinds of microorganisms. Terms have been introduced to describe concepts and provide precise communication. This book is a valuable source of information for scientists and researchers engaged in germfree research as a biological tool.

Germfree and Gnotobiotic Animal Models

Germfree and Gnotobiotic Animal Models PDF

Author: Bernard S. Wostmann

Publisher: CRC Press

Published: 2020-03-25

Total Pages: 202

ISBN-13: 0429610890

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The germfree animal is reared in the laboratory to be bacteria free; its counterpart, the gnotobiotic animal, is exposed to select microorganisms. The need for such an animal model for use in biomedical studies was first expressed by Pasteur in the late 1800s. Subsequent development of germfree and gnotobiotic animals led to an explosion of studies on the effects of microflora and its components on the physiology and metabolism of the host. Germfree and Gnotobiotic Animal Models brings together the most notable points of early and recent studies and gives reference to the most pertinent literature.

Gnotobiotics

Gnotobiotics PDF

Author: Trenton R Schoeb

Publisher: Academic Press

Published: 2017-08-11

Total Pages: 428

ISBN-13: 0128045833

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Gnotobiotics summarizes and analyzes the research conducted on the use of gnotobiotes, providing detailed information regarding actual facility operation and derivation of gnotobiotic animals. In response to the development of new tools for microbiota and microbiome analysis, the increasing recognition of the various roles of microbiota in health and disease, and the consequent expanding demand for gnotobiotic animals for microbiota/microbiome related research, this volume collates the research of this expanding field into one definitive resource. Reviews and defines gnotobiotic animal species Analyzes microbiota in numerous contexts Presents detailed coverage of the protocols and operation of a gnotobiotic facility

Bodies Out of Control

Bodies Out of Control PDF

Author: Matthew Weinstein

Publisher: Peter Lang

Published: 2010

Total Pages: 164

ISBN-13: 9781433105159

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"What is the cultural politics of science, health, and disease in the U.S.? Bodies Out of Control explores this question through a series of case studies. From its in-depth examination of the discussions of sickle-cell anemia, schistosomiasis, and cancer in middle school and high school textbooks to its analysis of the news coverage of the anthrax attacks of 2001, the book reveals the entanglements of science, colonialism, nationalism, and identity. The book also explores how the meaning of science itself is worked through in public discourses, offering alternatively medical salvation, confusion, and a vision of a world without pleasure. Finally, to explore what agency and a critical practice of engaging science in classrooms and elsewhere might look like, the book turns to the writings of politicized human research subjects, which demonstrate a spectrum of possibilities for more democratic engagements with science. As a whole, the book emphasizes the importance of engaging texts critically in science education and the ways that the cultural politics of science works through images of human and institutional bodies in and out of control."--Publisher's description.

The Laboratory Rat

The Laboratory Rat PDF

Author: Mark A. Suckow

Publisher: Academic Press

Published: 2019-11-10

Total Pages: 1182

ISBN-13: 0128143398

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The third edition of The Laboratory Rat features updated information on a variety of topics, including rats as research models for basic and translational research in areas such as genomics, alcoholism, diabetes, metabolic syndrome, obesity, neuroscience, spinal cord injury, traumatic brain injury, regenerative medicine, and infectious disease. New information related to the husbandry and veterinary care of rats is provided including topics related to nutrition, reproduction, anesthesia and surgery, infectious and noninfectious disease, and the care of surgical and other fragile models. It is a premier source of information on the laboratory rat, this book will be of interest to veterinary and medical students, senior graduate students, postdocs and researchers who utilize animals in biomedical research. New chapters on the care of surgical and fragile models and on the use of rats in research areas such as alcoholism, regenerative medicine, spinal cord injury, traumatic brain injury, and others are included. All chapters were written by scientific and veterinary experts. This book condenses information from many sources on topics related to the care and use of rats in research. It is the premier source of information on the laboratory rat.

International Congress for Microbiology

International Congress for Microbiology PDF

Author: Sam Stuart

Publisher: Elsevier

Published: 2014-05-16

Total Pages: 641

ISBN-13: 1483137244

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IX International Congress for Microbiology discusses the genetic regulation of microbial metabolism. This book presents the recommendations and suggestions on the nomenclature and classification of viruses. Organized into eight parts encompassing 72 chapters, this compilation of papers starts with an overview of the genetic code, which expresses the relationship between nucleotide triplets in messenger RNA and amino acids in proteins. This text then discusses the two aspects of the regulation of the physiology of Escherichia coli. Other chapters explore the ergot alkaloids and examine the problem of ergot alkaloid production and biosynthesis. This book discusses as well the antibiotic inhibitors of protein synthesis that are major clinical drugs, including chloramphenicol, tetracycline, streptomycin, erythromycin, and other aminoglycosides. The final chapter deals with karyological investigation of the cells during transformation by Rous virus (RSV), which shows that these cells retain a diploid character. This book is a valuable resource for epidemiologists, microbiologists, and experts in infectious diseases.