Genetic Basis of Oral Health Conditions

Genetic Basis of Oral Health Conditions PDF

Author: Alexandre Rezende Vieira

Publisher: Springer Nature

Published: 2019-11-28

Total Pages: 114

ISBN-13: 3030144852

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This book explains the genetic basis of a wide range of dental disorders, including dental caries, periodontitis, congenital anomalies, malocclusions, orofacial pain, dental implant failure, and cancer. Such conditions are typically multifactorial or complex, with involvement of more than one gene as well as environmental influences. A sound grasp of this framework is ever more important, given the emergence of consumer genomics, including direct-to-consumer genetic testing. Dental professionals now need to understand why one person is susceptible to a particular oral health condition while a first-degree relative either does not develop the condition or does so in a less severe form. Knowledge of how genes operate in the susceptible host is essential if patients are to be offered accurate advice about their risks. The information provided in this book will assist in the delivery of effective personalized dental care through optimization of preventive strategies. It will enable the practitioner to explain the extent to which a patient’s condition is pure "bad luck", whether that bad luck can be changed by behavioral choices, and how many of our behaviors are influenced by genes.

Genomics, Personalized Medicine and Oral Disease

Genomics, Personalized Medicine and Oral Disease PDF

Author: Stephen T. Sonis, DMD, DMSc

Publisher: Springer

Published: 2015-09-17

Total Pages: 408

ISBN-13: 331917942X

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The objective of this book is to catalyze the application of genomics to the diagnosis and treatment of oral diseases by comprehensively presenting focused discussions on the current state of knowledge. The first section book provides basic information about genetics, genomics and personalized medicine and the informatical methods available to apply and organize genetic data so that it has clinical relevance. Recognizing the genetic robustness of the oral cavity, the introductory section includes chapters on the oral micro biome and host genomics and response to infectious agents. The next two sections contain chapters which describe the genomics of specific oral diseases and conditions, including the genetic basis for mechanism and risk of treatment toxicities associated with cancer therapy and bisphosphonates. Four chapters focus on gene-based therapies and the pharmacogenomics applied to oral disease. The final chapter presents a provocative summary which describes a comprehensive vision of the melding of genomics to personalized medicine and the potential actionable outcomes that will likely affect clinical practice in the upcoming years.

Handbook of Life Course Health Development

Handbook of Life Course Health Development PDF

Author: Neal Halfon

Publisher: Springer

Published: 2017-11-20

Total Pages: 667

ISBN-13: 3319471430

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This book is open access under a CC BY 4.0 license. ​This handbook synthesizes and analyzes the growing knowledge base on life course health development (LCHD) from the prenatal period through emerging adulthood, with implications for clinical practice and public health. It presents LCHD as an innovative field with a sound theoretical framework for understanding wellness and disease from a lifespan perspective, replacing previous medical, biopsychosocial, and early genomic models of health. Interdisciplinary chapters discuss major health concerns (diabetes, obesity), important less-studied conditions (hearing, kidney health), and large-scale issues (nutrition, adversity) from a lifespan viewpoint. In addition, chapters address methodological approaches and challenges by analyzing existing measures, studies, and surveys. The book concludes with the editors’ research agenda that proposes priorities for future LCHD research and its application to health care practice and health policy. Topics featured in the Handbook include: The prenatal period and its effect on child obesity and metabolic outcomes. Pregnancy complications and their effect on women’s cardiovascular health. A multi-level approach for obesity prevention in children. Application of the LCHD framework to autism spectrum disorder. Socioeconomic disadvantage and its influence on health development across the lifespan. The importance of nutrition to optimal health development across the lifespan. The Handbook of Life Course Health Development is a must-have resource for researchers, clinicians/professionals, and graduate students in developmental psychology/science; maternal and child health; social work; health economics; educational policy and politics; and medical law as well as many interrelated subdisciplines in psychology, medicine, public health, mental health, education, social welfare, economics, sociology, and law.

Genetic Basis of Oro-dental Diseases In Children

Genetic Basis of Oro-dental Diseases In Children PDF

Author: Aprajita Panwar

Publisher: LAP Lambert Academic Publishing

Published: 2012

Total Pages: 200

ISBN-13: 9783659214875

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This Book markedly emphasizes the Importance of a person to know about his Genetics. Genetics Had already proven its importance in art of knowing about the species from the basic cell of reproduction and also about the various features that a species adopt from his ancestors. Thousands of inherited Human disorders have been catalogued till date, but the underlying genetic causes of less than 20 percent of those disorders have been discovered so far. Studies of population, families, and twins have provided good evidence that genetic factors play an important role in almost every aspect of craniofacial growth and development including Oro-dental diseases like caries, periodontal diseases and malocclusion had provided major platform to work upon these genetic information. This book provides illustrative studies on genetic in the recent scenario regarding Oro-dental Diseases. A sincere effort has been made to describe the comprehensive aspect of genetic influence of oral diseases on a global aspect.

A Life Course Perspective on Health Trajectories and Transitions

A Life Course Perspective on Health Trajectories and Transitions PDF

Author: Claudine Burton-Jeangros

Publisher: Springer

Published: 2015-08-11

Total Pages: 213

ISBN-13: 331920484X

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This open access book examines health trajectories and health transitions at different stages of the life course, including childhood, adulthood and later life. It provides findings that assess the role of biological and social transitions on health status over time. The essays examine a wide range of health issues, including the consequences of military service on body mass index, childhood obesity and cardiovascular health, socio-economic inequalities in preventive health care use, depression and anxiety during the child rearing period, health trajectories and transitions in people with cystic fibrosis and oral health over the life course. The book addresses theoretical, empirical and methodological issues as well as examines different national contexts, which help to identify factors of vulnerability and potential resources that support resilience available for specific groups and/or populations. Health reflects the ability of individuals to adapt to their social environment. This book analyzes health as a dynamic experience. It examines how different aspects of individual health unfold over time as a result of aging but also in relation to changing socioeconomic conditions. It also offers readers potential insights into public policies that affect the health status of a population.

Oxford Textbook of Global Public Health

Oxford Textbook of Global Public Health PDF

Author: Roger Detels

Publisher: Oxford University Press

Published: 2017

Total Pages: 1717

ISBN-13: 019881013X

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Sixth edition of the hugely successful, internationally recognised textbook on global public health and epidemiology, with 3 volumes comprehensively covering the scope, methods, and practice of the discipline

The Veterinary Dental Patient: A Multidisciplinary Approach

The Veterinary Dental Patient: A Multidisciplinary Approach PDF

Author: Jerzy Gawor

Publisher: John Wiley & Sons

Published: 2021-07-09

Total Pages: 88

ISBN-13: 1118974689

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Provides an interdisciplinary approach to the veterinary dental patient and offers guidance on all aspects of integrating dentistry into veterinary general practice The Veterinary Dental Patient: A Multidisciplinary Approach helps veterinarians understand the dental aspects of every canine and feline patient and shows them how to effectively manage their oral health. It also provides guidance to the rest of the veterinary team so they can offer a coordinated approach when recommending and performing veterinary dentistry as a regular part of general practice. Edited by two prominent veterinary dentists who are Board Certified in both Europe and the United States, the text includes the latest information on safe anesthetic and monitoring protocols, accurate diagnosis and management, and referring patients to specialists. Chapters cover: establishing a dental presence in general veterinary practice; nutrition, oral health, and feeding dental patients; local, regional, and systemic complications of dental diseases; pain management; ophthalmic considerations; common situations for malpractice and mistakes; oral and maxillofacial surgery; extraction techniques and equipment; drug dosages and more. The book also offers several helpful appendixes. The Veterinary Dental Patient: A Multidisciplinary Approach is an essential book for all vets in general small animal practice as well as the wider veterinary team, including managers, veterinary nurses and technicians, and administrative staff.

Oral Epidemiology

Oral Epidemiology PDF

Author: Marco A. Peres

Publisher: Springer Nature

Published: 2020-10-19

Total Pages: 536

ISBN-13: 303050123X

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This intermediate textbook on oral epidemiology is designed to meet the needs of advanced students in the fields of Dentistry and Oral Health and dentists in the early stages of their career. Readers will find detailed information on the epidemiology of individual diseases and disorders and on hot topics and methods in oral health research. The extensive first part of the book explores the international epidemiological literature regarding a wide range of conditions, from dental caries and periodontal diseases to halitosis and malocclusions. In each case, the prevalence, disease-specific measures, and associated factors are identified. Attention is then focused on cutting-edge research topics in oral epidemiology, such as the intriguing mechanisms linking oral diseases and chronic general diseases, life course epidemiology, and the role of socioeconomic determinants of oral health. The final part of the book is devoted to description of the epidemiological methods and tools applied in the field of oral health. Here, the coverage includes validation of questionnaires, data collection and data analyses, and systematic reviews and meta-analyses.