Gene-Mapping Techniques and Applications

Gene-Mapping Techniques and Applications PDF

Author: Lawrence B. Schook

Publisher: CRC Press

Published: 2020-07-24

Total Pages: 353

ISBN-13: 100010463X

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This book explains current strategies for mapping genomes of higher organisms and explores applications of gene mapping to agriculturally important species of plants and animals. It also explores the experimental techniques used for genetic and physical mapping of genes.

Mapping and Sequencing the Human Genome

Mapping and Sequencing the Human Genome PDF

Author: National Research Council

Publisher: National Academies Press

Published: 1988-01-01

Total Pages: 128

ISBN-13: 0309038405

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There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

Genome Mapping and Genomics in Human and Non-Human Primates

Genome Mapping and Genomics in Human and Non-Human Primates PDF

Author: Ravindranath Duggirala

Publisher: Springer

Published: 2015-03-25

Total Pages: 305

ISBN-13: 3662463067

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This book provides an introduction to the latest gene mapping techniques and their applications in biomedical research and evolutionary biology. It especially highlights the advances made in large-scale genomic sequencing. Results of studies that illustrate how the new approaches have improved our understanding of the genetic basis of complex phenotypes including multifactorial diseases (e.g., cardiovascular disease, type 2 diabetes, and obesity), anatomic characteristics (e.g., the craniofacial complex), and neurological and behavioral phenotypes (e.g., human brain structure and nonhuman primate behavior) are presented. Topics covered include linkage and association methods, gene expression, copy number variation, next-generation sequencing, comparative genomics, population structure, and a discussion of the Human Genome Project. Further included are discussions of the use of statistical genetic and genetic epidemiologic techniques to decipher the genetic architecture of normal and disease-related complex phenotypes using data from both humans and non-human primates.

Genetic Mapping and Marker Assisted Selection

Genetic Mapping and Marker Assisted Selection PDF

Author: N. Manikanda Boopathi

Publisher: Springer Nature

Published: 2020-04-07

Total Pages: 504

ISBN-13: 9811529493

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The first edition of this book, Genetic Mapping and Marker Assisted Selection: Basics, Practice and Benefits, was widely appreciated as the first of its kind on this topic and has been listed as a reference work in several agricultural universities’ curricula. A great deal has happened over the last five years, making it high time to incorporate recent developments in genetic mapping and report on novel strategies in marker assisted selection in crop plants as a second edition. This book addresses a range of topics, including: new marker types and their genotyping methods based on high-throughput technologies, advances in genomics and their role in new marker development, improvements in genetic mapping strategies and software updates, developments in phenomics and their applications in QTL mapping, and how to incorporate these developments and advances in marker assisted selection in crop plants. Similar to the first edition, each technique and method is explained using a step-by-step method, allowing the book to serve as a self-study guide for scholars whose work involves the genetic improvement of crop plants for any trait of interest, particularly for biotic and abiotic stress resistance. In addition, the book offers a valuable guide for undergraduate and graduate students at agricultural universities and institutes that are interested and/or involved in the genetic improvement of crop plants using modern tools. In addition, the bibliography includes a list of suggested works for pursuing further research on the topics covered.

Calculating the Secrets of Life

Calculating the Secrets of Life PDF

Author: National Research Council

Publisher: National Academies Press

Published: 1995-04-06

Total Pages: 300

ISBN-13: 0309048869

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As researchers have pursued biology's secrets to the molecular level, mathematical and computer sciences have played an increasingly important roleâ€"in genome mapping, population genetics, and even the controversial search for "Eve," hypothetical mother of the human race. In this first-ever survey of the partnership between the two fields, leading experts look at how mathematical research and methods have made possible important discoveries in biology. The volume explores how differential geometry, topology, and differential mechanics have allowed researchers to "wind" and "unwind" DNA's double helix to understand the phenomenon of supercoiling. It explains how mathematical tools are revealing the workings of enzymes and proteins. And it describes how mathematicians are detecting echoes from the origin of life by applying stochastic and statistical theory to the study of DNA sequences. This informative and motivational book will be of interest to researchers, research administrators, and educators and students in mathematics, computer sciences, and biology.

Linkage Disequilibrium and Association Mapping

Linkage Disequilibrium and Association Mapping PDF

Author: Andrew R. Collins

Publisher: Springer Science & Business Media

Published: 2008-02-05

Total Pages: 529

ISBN-13: 1597453897

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As researchers continue to make enormous progress in mapping disease genes, exciting, novel, and complex analyses have emerged. In this book, scientists from around the world, who are leaders in this field, contribute their vast experience and expertise to produce a comprehensive and fascinating text for researchers and clinicians alike. They provide cutting-edge analysis of the most up-to-date and preeminent information available.

Gene Mapping

Gene Mapping PDF

Author: George J. Annas

Publisher: Oxford University Press, USA

Published: 1992

Total Pages: 330

ISBN-13:

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This timely work brings together a group of the nation's leading experts in genetics, medicine, history of science, health, law, philosophy of science, and medical ethics to assess the current state of modern human genetics, and to begin to chart the legal and ethical guidelines needed to prevent the misuse of human genetics from leading to the abuse of human beings. The six sections of the book, read together, map the social policy con tours of modern human genetics. The first part describes the science of the Human Genome Project. The second addresses specific social policy implications, including the relevance of recombinant DNA history, the eugenics legacy, military applications, and issues of race and class in the context of genetic discrimination. Broader philosophical issues, including reductionism and determinism, the concept of disease, and using germline gene therapy to "improve" human beings are discussed in the third part.

Gene Isolation and Mapping Protocols

Gene Isolation and Mapping Protocols PDF

Author: Jacqueline Boultwood

Publisher: Methods in Molecular Biology

Published: 1997

Total Pages: 334

ISBN-13:

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An unprecedented collection of all the most up-to-date techniques for gene isolation and mapping, including the latest methods for gene characterization using database analyses. This collection of thoroughly tested recipes also includes chapters for the computational analysis of novel cDNA sequences with up-to-the-minute information on basic sequence analysis, sequence similarity searches, exon detection and similarity searches, and the prediction of gene function. Its state-of-the-art methods constitute indispensable tools for all scientists engaged in the search for specific disease genes, or in the general advancement of the human genome project.

Principles of Biology

Principles of Biology PDF

Author: Lisa Bartee

Publisher:

Published: 2017

Total Pages:

ISBN-13: 9781636350417

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The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research.

Principles and Practices of Plant Genomics, Vol. 1

Principles and Practices of Plant Genomics, Vol. 1 PDF

Author: C Kole

Publisher: CRC Press

Published: 2008-01-03

Total Pages: 432

ISBN-13:

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"The three volumes in this series ... containing 41 chapters contributed by over [one] hundred globally reputed scientists, provide lucid deliberations on the concepts, strategies, tools, methodologies and achievements of plant genomics presented in a typical class-room approach."--Back cover.