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Fundamentals Of Radiation Biology

Author: Susan B Klein

Publisher: World Scientific

Published: 2023-01-04

Total Pages: 399

ISBN-13: 9811257671

Fundamentals of Radiation Biology presents a contemporary, comprehensive review of the interactions between ionizing radiations and biological materials, tracking the consequences to three inevitable endpoints: cell restitution, cell death, or cell transformation.The introductory narrative is followed by examination of larger scale phenomena including tissue responses to radiation injury, organ failure modes, and resultant human illness including cancer. Ultimately, Fundamentals of Radiation Biology considers circumstantial radiation incidents impacting biological systems including radiological terrorism and radiation pollution remediation. Chapters presenting an overview of carcinogenesis and radiation therapy techniques based in radiobiology discuss two significant expansions central to the concerns of the text.This book takes an unprecedented narrative approach to radiobiology; each chapter expands on the fundamentals surveyed previously to lead the reader steadily to a panorama of radiation biocomplexity. No biological event happens in isolation. Actions evoke reactions that alter structures and cause living systems to adapt. It also examines the components constituting mammalian radiation response machinery and correlates them with resultant physiological behaviors.

Fundamentals of Radiobiology

Author: Z. M. Bacq

Publisher: Elsevier

Published: 2013-10-22

Total Pages: 601

ISBN-13: 1483184528

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Fundamentals of Radiobiology presents a clear picture of the effects of radiation to living organisms. It discusses the steps leading from the absorption of energy to death or final injury. The focus of study is the changes induced at the molecular level by absorbing energy. Some of the topics covered in the book are the methods for determining the direct and indirect action in biological systems, the nature of the initial chemical lesion in cellular radiobiology, the definition of target theory and the meaning of poison theory. The subjects on general radiation chemistry are also covered. The fields of radiation chemistry that will be discussed are the role of excitation, the variation of reactions between gases, liquids, and solids; and the status of free radicals created. The effects of radiation on macromolecules are discussed. The text defines the important role of metabolism in the development of the lesions. An analysis of the interactions of ionizing radiations with is presented. A chapter of the volume is devoted to the radiation chemistry of aqueous systems. Another section of the book focuses on the chemicals which simulate the biological effects of ionizing radiations. The book will provide useful information to doctors, chemists, biologists, radiologists, students and researchers.

Introduction To Radiobiology

Author: Maurice Tubiana

Publisher: CRC Press

Published: 2005-10-10

Total Pages: 269

ISBN-13: 0203983661

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This textbook covers many aspects of radiation, radiotherapy and their effects. It includes a discussion of recent advances, such as the molecular basis of cellular effects and cell radiosensitivity, radiocarcinogenesis and how radiotherapy can affect normal and neoplastic tissues.

Introduction to Radiobiology

Author: J. Dutreix

Publisher: CRC Press

Published: 1990-09-01

Total Pages: 618

ISBN-13: 9780850667455

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This textbook covers all aspects of radiation, radiotherapy and their effects. The book, initially published in France, has been updated and expanded in this English version. It includes a thorough discussion of recent advances, such as a better understanding of the molecular basis of cellular effects and cell radiosensitivity.There is a study of the mechanmism by which dose and overall duration of radiotherapy can introoduce differential effects between normal and neoplastic tissues and recent data on radiocarcinogenesis in man and experimental animals is provided.

Fundamentals of Radiation Oncology

Author: Hasan Murshed

Publisher: Elsevier

Published: 2024-06-28

Total Pages: 570

ISBN-13: 0443222096

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Fundamentals of Radiation Oncology: Physical, Biological, and Clinical Aspects, Fourth Edition, is written by a team of renowned experts. This book is a must-have resource for anyone practicing radiation oncology. From basic principles to more-advanced planning and delivery of radiation therapy to treat cancer, this book is a go-to resource for mastering the art and science of radiation oncology. Recent advances in SRS, SBRT, proton therapy, an immunotherapy New chapters on adaptive radiotherapy, and artificial intelligence in radiation therapy IMRT and IGRT techniques are covered in depth in all clinical chapters Latest landmark studies provide evidence-based rationale for recommended treatments Radiation treatment toxicity and its management

Radiobiology Self-Assessment Guide

Author: Jennifer Yu, MD, PhD

Publisher: Springer Publishing Company

Published: 2016-11-03

Total Pages: 520

ISBN-13: 1617052914

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Radiobiology Self-Assessment Guide--a companion to the Radiation Oncology Self-Assessment Guide and Physics in Radiation Oncology Self-Assessment Guide--is a comprehensive review for practitioners of radiation oncology looking to enhance their knowledge of radiobiology. It covers in depth the principles of radiobiology as applied to radiation oncology along with their clinical applications. To foster retention of key concepts and data, the resource utilizes a user-friendly "flash card" question and answer format with over 700 questions. The questions are supported by detailed answers and rationales along with reference citations for source information. The guide is comprised of 29 chapters and cover topics commonly found on the radiation and cancer biology portion of the radiation oncology board examination. Aspects of basic radiobiology covered include fundamentals such as cell cycle, cell survival curves and interactions of radiation with matter, and acute and long-term sequelae of radiation. Modern concepts such as immunotherapy, radiogenomics, and normal and cancer stem cells are also included. Focused and authoritative, this must-have review provides the expertise of faculty from the Department of Radiation Oncology at the Cleveland Clinic Taussig Cancer Institute and Lerner Research Institute. Key Features: Provides a comprehensive study guide for the Radiation and Cancer Biology portion to the Radiation Oncology Board Exam Includes more than 700 questions with detailed answers and rationales on flip pages for easy, flash card-like review Includes essential review of cancer biology concepts such as immunotherapy, stem cells, gene therapy, chemotherapy and targeted agents Content provided by a vast array of contributors, including attending radiation oncology physicians, physicists, and radiation oncology residents

Adverse Reproductive Outcomes in Families of Atomic Veterans

Author: Institute of Medicine

Publisher: National Academies Press

Published: 1995-07-17

Total Pages: 107

ISBN-13: 0309176115

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Over the past several decades, public concern over exposure to ionizing radiation has increased. This concern has manifested itself in different ways depending on the perception of risk to different individuals and different groups and the circumstances of their exposure. One such group are those U.S. servicemen (the "Atomic Veterans" who participated in the atmospheric testing of nuclear weapons at the Nevada Test Site or in the Pacific Proving Grounds, who served with occupation forces in or near Hiroshima and Nagasaki, or who were prisoners of war in or near those cities at the time of, or shortly after, the atomic bombings. This book addresses the feasibility of conducting an epidemiologic study to determine if there is an increased risk of adverse reproductive outcomes in the spouses, children, and grandchildren of the Atomic Veterans.

Fundamentals of Radiobiology

Author: Zénon Marcel Bacq

Publisher:

Published: 1963

Total Pages: 562

ISBN-13:

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Interaction of ionizing radiations with matter; Direct and indirect action in biological systems; Dose-response relationships in chemical and biological systems; The nature of the initial chemical Lesion in cellular radiobiology; General radiation chemistry; The radiation chemistry of aqueous systems; Effect of radiation on macromolecules; Chemical substances which simulate the biological effects; Effects at the cellular Level; Biochemical Medranism for cellular effects the enzyme release hypothesis; The effect of oxygen in radiobiology; Comparative radiosensitivity of living organisms; Pathological Biochemisty of irradiated living organisms; Processes of restoration after irradiation; Heuro-endocrine reactions in radiation sickness; Physiopathology of radiatiation sickness in mammals; Delayed effects; Interaction between cells and tissues follwing irradiation; Chemical protection against Xand Gamma-rays; Treatment by Rone-Marrow and spleen cells; Human Experience.

Introduction to Radiobiology

Author: A. H. W. Nias

Publisher:

Published: 1990-11-02

Total Pages: 364

ISBN-13:

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Provides an introduction to quantitative radiobiology with emphasis on practical aspects of the subject. Readers will gain a ready understanding of both the very fast processes which initiate damage in irradiated tissue and the kinetic patterns in which such damage is expressed at the cellular level. Among the topics considered are reparable damage, densely ionizing radiation, normal and malignant cells and whole body regulation. These and other aspects of radiation biology are described in detail at a level appropriate to readers with a basic knowledge of mammalian cell biology.

An Introduction to Radiobiology

Author: A. H. W. Nias

Publisher: John Wiley & Sons

Published: 1998-06-11

Total Pages: 408

ISBN-13: 9780471975908

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This new edition of A.H.W. Nias' successful book provides an updated and revised introduction to quantitative radiobiology, particularly, to those aspects of the subject which have a practical application. Radiation is used to cure cancer but can also cause it. Radiation is also used in medical diagnosis and in nuclear power stations. In these areas, where questions of benefit and detriment arise, the biological effects of the radiation can now be predicted. There are few aspects of life where risk estimates are so firmly founded on quantitative data. This is not only because of the precision with which radiation dose can be measured but also because of the large body of radiobiological observations which have been made since X-rays were discovered. Written by a scientist with many years experience in the field, An Introduction to Radiobiology will appeal to a wide variety of readers who need to understand the mechanisms by which ionizing radiation causes cellular damage. It will be of interest to technologists in radiation therapy, nuclear medicine and diagnostic radiography, cancer research students and technicians, medical physicists, trainee radiotherapists and nuclear medicine specialists. Reviews of the First Edition: "In summary, this is an excellent general text that should fill an important gap in many teaching needs, especially those where the major focus is on the biological effects of radiation on humans." Journal of the National Cancer Institute "This is undoubtedly one of the better introductions to the subject which I have read, and I would certainly recommend it not only to beginners but also to mature students of the subject." The British Journal of Radiology