From Breakthrough to Blockbuster

From Breakthrough to Blockbuster PDF

Author: Donald L. Drakeman

Publisher: Oxford University Press

Published: 2022

Total Pages: 241

ISBN-13: 0195084004

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"Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources. How could a large collection of small companies, most with fewer than 50 employees, compete in one of the world's most breathtakingly expensive and highly regulated industries? This book shows how biotech companies have met the challenge by creating nearly 40% more of the most important treatments for unmet medical needs. Moreover, they have done so with much lower overall costs. The book focuses on both the companies themselves and the broader biotech ecosystem that supports them. Its portrait of the crucial roles played by academic research, venture capital, contract research organizations, the capital markets, and pharmaceutical companies shows how a supportive environment enabled the entrepreneurial biotech industry to create novel medicines with unprecedented efficiency. In doing so, it also offers insights for any industry seeking to innovate in uncertain and ambiguous conditions. Looking to the future, it concludes that biomedical research will continue to be most effective in the hands of a large group of small companies as long as national healthcare policies allow the rest of the ecosystem to continue to thrive"--

From Breakthrough to Blockbuster

From Breakthrough to Blockbuster PDF

Author: Donald L. Drakeman

Publisher: Oxford University Press

Published: 2022-02-14

Total Pages: 241

ISBN-13: 0197626300

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Financial Times Business Top Title March 2022 How could a large collection of small companies, most with fewer than 50 employees, rise to compete with Big Pharma, one of the world's most breathtakingly expensive and highly regulated industries? Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources. Biotech companies have met the challenge by creating nearly 40% more of the most important treatments for previously unmet medical needs. Moreover, they have done so with much lower overall costs. From Breakthrough to Blockbuster: The Business of Biotechnology focuses on both the companies themselves and the broader biotech ecosystem that supports them. It paints a portrait of the crucial roles played by academic research, venture capital, contract research organizations, the capital markets, and pharmaceutical companies, demonstrating how a supportive environment enabled the entrepreneurial biotech industry to create novel medicines with unprecedented efficiency. In doing so, it also offers insights for any industry seeking to innovate in uncertain and ambiguous conditions.

Science Lessons

Science Lessons PDF

Author: Gordon M. Binder

Publisher: Harvard Business Review Press

Published: 2008

Total Pages: 326

ISBN-13:

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Under Gordon Binder's leadership, Amgen became the world's largest and most successful biotech company in the world. This text describes what it really takes to manage risk, financing, creative employees, and intellectual property on the international stage.

Science Business

Science Business PDF

Author: Gary P. Pisano

Publisher: Harvard Business Press

Published: 2006

Total Pages: 278

ISBN-13: 9781591398400

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Why has the biotechnology industry failed to perform up to expectations? This book attempts to answer this question by providing a critique of the industry. It reveals the causes of biotech's problems and offers an analysis on how the industry works. It also provides prescriptions for companies, seeking ways to improve the industry's performance.

Instant Appeal

Instant Appeal PDF

Author: Vicki KUNKEL

Publisher: Amacom Books

Published: 2008-11-26

Total Pages: 306

ISBN-13: 0814410219

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Discover the hidden secrets of mass appeal...and use them to create unbreakable allegiance for products, people, and ideas!

Blockbuster Drugs

Blockbuster Drugs PDF

Author: Jie Jack Li

Publisher: Oxford University Press

Published: 2014

Total Pages: 238

ISBN-13: 0199737681

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"This book uses the cases of several landmark drugs to discuss the history of the pharmaceutical industry, and discusses what could be next"--Provided by publisher.

From Alchemy To Ipo

From Alchemy To Ipo PDF

Author: Cynthia Robbins-roth

Publisher: Perseus Books

Published: 2000-05-18

Total Pages: 280

ISBN-13:

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A fascinating glimpse inside the life-and-death business of biotechnology.

Can't Slow Down

Can't Slow Down PDF

Author: Michaelangelo Matos

Publisher: Hachette Books

Published: 2020-12-08

Total Pages: 480

ISBN-13: 0306903350

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A Rolling Stone-Kirkus Best Music Book of 2020 The definitive account of pop music in the mid-eighties, from Prince and Madonna to the underground hip-hop, indie rock, and club scenes Everybody knows the hits of 1984 - pop music's greatest year. From "Thriller" to "Purple Rain," "Hello" to "Against All Odds," "What's Love Got to Do with It" to "Wake Me Up Before You Go-Go," these iconic songs continue to dominate advertising, karaoke nights, and the soundtracks for film classics (Boogie Nights) and TV hits (Stranger Things). But the story of that thrilling, turbulent time, an era when Top 40 radio was both the leading edge of popular culture and a moral battleground, has never been told with the full detail it deserves - until now. Can't Slow Down is the definitive portrait of the exploding world of mid-eighties pop and the time it defined, from Cold War anxiety to the home-computer revolution. Big acts like Michael Jackson (Thriller), Prince (Purple Rain), Madonna (Like a Virgin), Bruce Springsteen (Born in the U.S.A.), and George Michael (Wham!'s Make It Big) rubbed shoulders with the stars of the fermenting scenes of hip-hop, indie rock, and club music. Rigorously researched, mapping the entire terrain of American pop, with crucial side trips to the UK and Jamaica, from the biz to the stars to the upstarts and beyond, Can't Slow Down is a vivid journey to the very moment when pop was remaking itself, and the culture at large - one hit at a time.

Ben Franklin's Fame

Ben Franklin's Fame PDF

Author: Stacia Deutsch

Publisher: Simon and Schuster

Published: 2014-09-02

Total Pages: 128

ISBN-13: 144249347X

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When Benjamin Franklin decides to quit, it’s up to the Blast to the Past friends to find him and get history back on track in this sixth book in the Blast to the Past series. Abigail and her friends can’t believe it—Babs Magee has finally convinced someone to quit, and that someone is Benjamin Franklin! Not only is he an important Founding Father, he invented the lightning rod, bifocals, and more. Babs is making a terrible mess of history, and it’s up to the third-grade time travelers to put things right. But no matter how far back the kids go, Babs is always one step ahead of them. Will they be able to find Ben and stop Babs in time to save history?

Hedy's Folly

Hedy's Folly PDF

Author: Richard Rhodes

Publisher: Vintage

Published: 2012-08-07

Total Pages: 298

ISBN-13: 0307742954

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Pulitzer Prize-winning author Richard Rhodes delivers a remarkable story of science history: how a ravishing film star and an avant-garde composer invented spread-spectrum radio, the technology that made wireless phones, GPS systems, and many other devices possible. Beginning at a Hollywood dinner table, Hedy's Folly tells a wild story of innovation that culminates in U.S. patent number 2,292,387 for a "secret communication system." Along the way Rhodes weaves together Hollywood’s golden era, the history of Vienna, 1920s Paris, weapons design, music, a tutorial on patent law and a brief treatise on transmission technology. Narrated with the rigor and charisma we've come to expect of Rhodes, it is a remarkable narrative adventure about spread-spectrum radio's genesis and unlikely amateur inventors collaborating to change the world.