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Fluorescent Organic Nanoparticles

Author: Waseem A. Wani

Publisher: Springer

Published: 2018-09-27

Total Pages: 63

ISBN-13: 981132655X

This book provides a critical review of recent advances in the development of fluorescent organic nanoparticles as materials of choice for the design and fabrication of sensors, bioimaging agents and drug delivery systems. The properties and functions of nanoparticles differ significantly from those of their parent entities or their bulk phases. Two of their most important features are their increased surface-to volume ratio, and the formation of surface structures differing from those in their bulk phases. In addition, the book discusses the synthesis of fluorescent conjugated polymers, self-assembled fluorescent nanoparticles, polydopamine nanoparticles, and aggregation-induced-emission or aggregation-induced-emission enhancement nanomaterials. In closing, the book provides an outlook on future research and development in fluorescent organic nanoparticles as smart materials with an impressive range of potential applications.

Fluorescent Organic Nanoparticles

Author: Waseem A. Wani

Publisher:

Published: 2018

Total Pages:

ISBN-13: 9789811326561

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Functional Fluorescent Organic Nanoparticles

Author: Elisa Campioli

Publisher:

Published: 2013

Total Pages: 0

ISBN-13:

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During the past two decades, increasing research attention has been devoted to nanomaterials (materials in the range of 10-100 nm) because of their unique optoelectronic properties. In particular, inorganic nanomaterials, such as quantum dots, metal-based nanoparticles and silica nanoparticles, have been investigated extensively. Instead, nanomaterials based on organic molecules are been subject of research only since very recent years. This thesis presents an extensive study of novel fluorescent organic nanoparticles and fluorescent organic binary and ternary nanoassemblies. In particular the attention is focused on the preparation and characterization of organic nanoparticles and new nanocomposites obtained from different types of small organic chromophores, their stabilization and the use of these materials for biological and optoelectronics applications.

Aquatic Organic Matter Fluorescence

Author: Paula G. Coble

Publisher: Cambridge University Press

Published: 2014-07-14

Total Pages: 407

ISBN-13: 0521764610

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A core text on principles, laboratory/field methodologies, and data interpretation for fluorescence applications in aquatic science, for advanced students and researchers.

Synthesis of Fluorescent Organic Nanoparticles for Biological Applications

Author: Ievgen Shulov

Publisher:

Published: 2016

Total Pages: 0

ISBN-13:

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Quantum dots (QDs) and fluorescent silica nanoparticles (NPs) have impacted the domain of bioimaging by their high brightness and robust photostability. In comparison to QDs, organic NPs can be even brighter and fully biodegradable, as well biocompatible and not containing toxic elements inside. Herein, we developed four types of these NPs. At first, lipid nano-droplets loaded with lipophilic flavone and Nile Red dyes for in vivo imaging in zebrafish; second, ion-association of alkyl rhodamine B with fluorinated tetraphenylborate (TPB) counterions result in 11-20 nm NPs with fluorescence quantum yield up to 60%; third, 7 nm micellar NPs obtained by co-assembly of cyanine amphiphiles with TPB counterions; finally, polymerization of calix[4]arene micelles using bi-functional cyanine crosslinkers giving 7 nm NPs, that show fluorogenic behavior and high intracellular stability. These NPs, being of smaller size and brighter than QDs, have emerged as promising tools for bioimaging.

Controlled Switching of Fluorescent Organic Nanoparticles Through Energy Transfer for Bioimaging Applications

Author: Kateryna Trofymchuk

Publisher:

Published: 2016

Total Pages: 0

ISBN-13:

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Performance of biosensing and bioimaging techniques can be improved by fluorescent nanoparticles (NPs) capable of efficient Förster resonance energy transfer (FRET). The aim of my PhD project is to develop bright and photostable dye-loaded polymer NPs capable to undergo efficient FRET beyond the Förster radius. We showed that bulky groups are essential for minimizing self-quenching and bleaching of encapsulated dyes. Moreover, polymer matrix plays a crucial role in controlling the inter-fluorophore communication by excitation energy transfer. Then, by exploiting communication of dyes, we designed NPs exhibiting efficient photoswitching as well as giant light-harvesting. Finally, very small NPs with efficient FRET to their surface were developed and applied for ultra-sensitive molecule detection of proteins. The obtained results provide new insights in the development of bright nanoparticles with efficient energy transfer as well as nano-probes for single-molecule detection.

Metal-Enhanced Fluorescence

Author: Chris D. Geddes

Publisher: John Wiley & Sons

Published: 2010-06-22

Total Pages: 655

ISBN-13: 0470642785

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Discover how metal-enhanced fluorescence is changing traditional concepts of fluorescence This book collects and analyzes all the current trends, opinions, and emerging hot topics in the field of metal-enhanced fluorescence (MEF). Readers learn how this emerging technology enhances the utility of current fluorescence-based approaches. For example, MEF can be used to better detect and track specific molecules that may be present in very low quantities in either clinical samples or biological systems. Author Chris Geddes, a noted pioneer in the field, not only explains the fundamentals of metal-enhanced fluorescence, but also the significance of all the most recent findings and models in the field. Metal-enhanced fluorescence refers to the use of metal colloids and nanoscale metallic particles in fluorescence systems. It offers researchers the opportunity to modify the basic properties of fluorophores in both near- and far-field fluorescence formats. Benefits of metal-enhanced fluorescence compared to traditional fluorescence include: Increased efficiency of fluorescence emission Increased detection sensitivity Protect against fluorophore photobleaching Applicability to almost any molecule, including both intrinsic and extrinsic chromophores Following a discussion of the principles and fundamentals, the author examines the process and applications of metal-enhanced fluorescence. Throughout the book, references lead to the primary literature, facilitating in-depth investigations into particular topics. Guiding readers from the basics to state-of-the-technology applications, this book is recommended for all chemists, physicists, and biomedical engineers working in the field of fluorescence.

Nanomaterials: A Danger or a Promise?

Author: Roberta Brayner

Publisher: Springer Science & Business Media

Published: 2012-08-10

Total Pages: 398

ISBN-13: 1447142136

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With the increased presence of nanomaterials in commercial products such as cosmetics and sunscreens, fillers in dental fillings, water filtration process, catalysis, photovoltaic cells, bio-detection, a growing public debate is emerging on toxicological and environmental effects of direct and indirect exposure to these materials. Nanomaterials: A Danger or a Promise? forms a balanced overview of the health and environmental issues of nanoscale materials. By considering both the benefits and risks associated with nanomaterials, Nanomaterials: A Danger or a Promise? compiles a complete and detailed image of the many aspects of the interface between nanomaterials and their real-life application. The full cycle of nanomaterials life will be presented and critically assessed to consider and answer questions such as: How are nanomaterials made? What they are used for? What is their environmental fate? Can we make them better? Including coverage of relevant aspects about the toxicity of manufactured nanomaterials, nanomaterials life cycle, exposure issues, Nanomaterials: A Danger or a Promise? provides a comprehensive overview of the actual knowledge in these fields but also presents perspectives for the future development of a safer nanoscience. This comprehensive resource is a key reference for students, researcher, manufacturers and industry professionals alike.

Electrogenerated Chemiluminescence of Organic Nanoparticles

Author: Omer Khalid

Publisher: LAP Lambert Academic Publishing

Published: 2014-12-09

Total Pages: 180

ISBN-13: 9783659647994

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Electrogenerated chemiluminescence of organic nanoparticles has been observed and described. Highly fluorescent organic nanoparticles may emit light upon applying a certain potential on their aqueous or nano aqueous solutions, even in the their solid state films. Such phenomenon will open a vast realm of tailoring many types of fluorophores and organic nanoparticles in order to get unique physical, mechanical, biological, and optical properties in material sciences area.

Fluorescence Methods for Investigation of Living Cells and Microorganisms

Author: Natalia Grigoryeva

Publisher: BoD – Books on Demand

Published: 2020-09

Total Pages: 464

ISBN-13: 1839680393

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Fluorescence methods play a leading role in the investigation of biological objects. They are the only non-destructive methods for investigating living cells and microorganisms in vivo. Using intrinsic and artificial fluorescence methods provides deep insight into mechanisms underlying physiological and biochemical processes. This book covers a wide range of modern methods involved in experimental biology. It illustrates the use of fluorescence microscopy and spectroscopy, confocal laser scanning microscopy, flow cytometry, delayed fluorescence, pulse-amplitude-modulation fluorometry, and fluorescent dye staining protocols. This book provides an overview of practical and theoretical aspects of fluorescence methods and their successful application in the investigation of static and dynamic processes in living cells and microorganisms.