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Flow Dynamics and Tissue Engineering of Blood Vessels

Author: Arindam Bit

Publisher: Myprint

Published: 2020-12

Total Pages: 316

ISBN-13: 9780750320894

Flow Dynamics and Tissue Engineering of Blood Vessels explores the physical phenomena of vessel compliance and its influence on blood flow dynamics, as well as the modification of flow structures in the presence of diseases within the vessel wall or diseased blood content. This volume also illustrates the progress of tissue engineering for the intervention of re-engineered blood vessels. Blood vessel organoid models, their controlling aspects, and blood vessels based on microfluidic platforms are illustrated following on from the understanding of flow physics of blood on a similar platform. The purpose of this book is to provide an overview of regenerative medicine and fluid mechanics principles for the management of clinically diseased blood vessels. Authors discuss tissue engineering aspects and computational fluid mechanical principles, and how they can be used to understand the state of blood vessels in diseased conditions. Key Features Computational and experimental fluid dynamics principles have been used to explore the modelling of diseased blood vessels Principles of fluid dynamics and tissue engineering are used to propose innovative designs of bioreactors for blood vessel regeneration Offers experimental analytical studies of blood flow in vessels with pathological conditions Controlling aspects of various parameters while developing blood-vessel bioreactors and organoid models are presented critically, and optimization techniques for these parameters are also provided

Vascular Engineering

Author: Kazuo Tanishita

Publisher: Springer

Published: 2016-03-17

Total Pages: 400

ISBN-13: 4431548017

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This book describes the fundamental biology and mechanics of the vasculature and examines how this knowledge has underpinned the development of new clinical modalities, including endovascular treatment and vascularization of reconstructed tissue for regenerative medicine. Vascular engineering is a multidisciplinary field integrating vascular biology, hemodynamics, biomechanics, tissue engineering, and medicine. Each chapter offers insights into the dynamics of the circulatory system and explains how the impact of related disease conditions — atherosclerosis, hypertension, myocardial ischemia, and cerebral infarction — has generated a focus on developing expertise to both maintain and treat the vascular system. As a comprehensive book in this expanding area, Vascular Engineering serves as a valuable resource for clinicians as well as academics and professionals working in biophysics, biomedical engineering, and nano and microrheology. Graduate students in these subject areas will also find this volume insightful.

Biofluid Mechanics

Author:

Publisher: CRC Press

Published: 2012-02-24

Total Pages: 456

ISBN-13: 1439845182

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Designed for senior undergraduate or first-year graduate students in biomedical engineering, Biofluid Mechanics: The Human Circulation, Second Edition teaches students how fluid mechanics is applied to the study of the human circulatory system. Reflecting changes in the field since the publication of its predecessor, this second edition has been ex

Biofluid Mechanics (Second Edition)

Author: Jagannath Mazumdar

Publisher: World Scientific

Published: 2015-12-08

Total Pages: 264

ISBN-13: 9814719013

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Biofluid mechanics is the study of a certain class of biological problems from the viewpoint of fluid mechanics. Though biofluid mechanics does not involve any new development of the general principles of fluid mechanics, it does involve some new applications of its methods. Complex movements of fluids in the biological system demand for an analysis achievable only with professional fluid mechanics skills, and this volume aims to equip readers with the knowledge needed.This second edition is an enlarged version of the book published in 1992. While retaining the general plan of the first edition, this new edition presents an engineering analysis of the cardiovascular system relevant to the treatment of cardiovascular diseases and combines engineering principles. Included in the material of this volume are: the emerging interdisciplinary field of tissue engineering, which deals with the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain and improve tissue function, and cellular and molecular bioengineering, which involves the mechanical, electrical and chemical processes of the human cell and tries to explain how cellular behaviour arises from molecular-level interactions.The added material in this edition is specifically designed for biomedical engineering professionals and students, and looks at the important applications of biofluid mechanics from an engineering perspective.

Biomedical Fluid Dynamics

Author: Troy Shinbrot

Publisher: Oxford University Press, USA

Published: 2019-03-07

Total Pages: 392

ISBN-13: 0198812582

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This is a readable and attractively presented textbook on fluid flow in biological systems that includes flow through blood vessels, pulsatile flow, and pattern formation. It bridges the divide among biomedical engineering students between those with an engineering and those with a bio-scientific background, by offering guidance in both physiological and mathematical aspects of the subject. Every chapter includes surprising, amusing, and stimulating effects that the reader may want to experiment on their own. Brief historical vignettes are also included throughout this book. We in the 21st century can so easily turn to the computer to provide a solution, that we forget the extraordinary sparks of insight that scientists in centuries past had to rely on to provide us with the foundational understanding and analytical tools that we now depend on. This book is an attempt to maintain our roots in past investigations, while giving us wings to explore future ones.

Biofluid Dynamics

Author: Clement Kleinstreuer

Publisher: CRC Press

Published: 2016-04-19

Total Pages: 525

ISBN-13: 1420003976

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Biofluid Dynamics builds a solid understanding of medical implants and devices from a bioengineering standpoint. The text features extensive worked examples and mathematical appendices; exercises and project assignments to stimulate critical thinking and build problem solving skills; numerous illustrations, including a 16-page full-color insert; computer simulations of biofluid dynamics processes and medical device operations; tools for solving basic biofluid problems; and a glossary of terms. The text can be used as a primary selection for a comprehensive course or for a two-course sequence or as a reference for professionals in biomedical engineering and medicine.

Cardiovascular Flow Dynamics and Measurements

Author: Ned H. C. Hwang

Publisher:

Published: 1977

Total Pages: 1066

ISBN-13:

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Molecular, Cellular, and Tissue Engineering of the Vascular System

Author: Bingmei M. Fu

Publisher: Springer

Published: 2018-10-12

Total Pages: 334

ISBN-13: 3319964453

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This book introduces the latest research in molecular, cellular, and tissue engineering of the vascular system. Topics covered include the roles of endothelial surface glycocalyx as a mechano-sensor and transducer for blood flow, a barrier to water and solute transport across the vascular wall and to the interaction between circulating cells and the vessel wall, the roles of nuclear envelope proteins and nuclear lamina in regulating vascular functions under blood flow-induced forces, and the roles of smooth muscle cells and extracellular components in arterial vasoconstriction. Other topics covered include non-surgical vascular interventions for coronary artery diseases, genesis and mechanisms of atherosclerotic plaque microcalcifications and human abdominal aortic aneurysms, experiments and modelling for red blood cell and tumor cell movement in microcirculation, transport across the blood-brain barrier and its role in Alzheimer’s disease, mathematical models for cell survival after hyperthermia, application of hypothermia in enhancing treatment for brain and spinal cord injuries, and damage of eardrums due to blast waves. This is an ideal book for biomedical engineers and researchers, medical researchers, and students in biomedical engineering and medical sciences.

Fluid Mechanics for Cardiovascular Engineering

Author: Gianni Pedrizzetti

Publisher: Springer Nature

Published: 2021-10-28

Total Pages: 231

ISBN-13: 3030859436

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This book provides a guiding thread between the distant fields of fluid mechanics and clinical cardiology. Well rooted in the science of fluid dynamics, it drives the reader across progressively more realistic scenarios up to the complexity of routine medical applications. Based on the author’s 25 years of collaborations with cardiologists, it helps engineers learn communicating with clinicians, yet maintaining the rigor of scientific disciplines. This book starts with a description of the fundamental elements of fluid dynamics in large blood vessels. This is achieved by introducing a rigorous physical background accompanied by examples applied to the circulation, and by presenting classic and recent results related to the application of fluid dynamics to the cardiovascular physiology. It then explores more advanced topics for a physics-based understanding of phenomena effectively encountered in clinical cardiology. It stands as an ideal learning resource for physicists and engineers working in cardiovascular fluid dynamics, industry engineers working on biomedical/cardiovascular technology, and students in bio-fluid dynamics. Written with a concise style, this textbook is accessible to a broad readership, including students, physical scientists and engineers, offering an entry point into this multi-disciplinary field. It includes key concepts exemplified by illustrations using cutting-edge imaging, references to modelling and measurement technologies, and includes unique original insights.

Hemo-Dynamics

Author: Mair Zamir

Publisher: Springer

Published: 2015-11-19

Total Pages: 423

ISBN-13: 3319241036

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Praise for Hemo-Dynamics: “This book provides an elegant and intuitive derivation of the fundamental mathematics underlying fluid flow, and then applies these in a straightforward way to pulsatile blood flow in all its complexity. One of the triumphs of the book is that Zamir succeeds in making essential concepts such as the Navier-Stokes equations completely accessible to any reader with a knowledge of basic calculus. The author succeeds in conveying both the beauty of his subject matter, and his passion for the elegance and intricacies of fluid flow more generally.” Lindi Wahl, PhD, Professor of Applied Mathematics, The University of Western Ontario “Incredible, the figures alone are to die for... At first glance “Hemo-Dynamics” seems like a deep engineering and modeling dive into the mechanical properties of the cardiovascular system, blood, and how they interact to generate flow and pressure. However, the text is laid out in a stepwise manner and I was especially impressed in the way that the key conceptual figures illustrate the essential concepts. In keeping with the philosophical underpinnings of engineering, Professor Zamir has also constructed his book so that the format, text, equations and the figures are self-reinforcing. This isa book that will be of great use to those who seek to understand the cardiovascular system from a mechanical and m odeling perspective.” Michael J. Joyner, MD, Professor of Anesthesiology, Mayo Clinic, Rochester, MN