Fast Facts: Recognizing Refractory Myasthenia Gravis

Fast Facts: Recognizing Refractory Myasthenia Gravis PDF

Author: Nicholas J. Silvestri

Publisher: Karger Medical and Scientific Publishers

Published: 2018-03-05

Total Pages: 49

ISBN-13: 1910797537

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An in-depth look at a rare disease Myasthenia gravis (MG) is a rare autoimmune disorder of the neuromuscular junction, characterized by muscle fatigability. Patients often initially present with ocular symptoms, but in most cases the disease spreads beyond the eye muscles to more generalized involvement of bulbar, facial, neck, proximal limb and respiratory muscles. With adequate treatment, most patients with MG are able to live productive lives with few or no symptoms, but a distinct subset of patients do not respond to conventional treatment. With new treatment options on the horizon, it is important that these patients are identified. 'Fast Facts: Recognizing Refractory Myasthenia Gravis' takes an in-depth look at: • the immune-mediated nature of MG • classification of MG by disease type and severity, and antibody status • clinical presentation and diagnostic work-up • conventional management options • how patients with treatment-refractory MG present • the assessment tools that can be used to identify non-responders. This informative resource will be of value to neurologists, neurology trainees and ophthalmologists caring for patients with this rare disease, as well as patients with MG who wish to have a deeper dialog with their doctor or patient group. Contents: • Definition and epidemiology • Pathophysiology and classification • Diagnosis and management: an overview • Assessment of disease severity and treatment response

Lippincott Fast Facts for NCLEX-RN

Lippincott Fast Facts for NCLEX-RN PDF

Author: Rebecca Cox-Davenport

Publisher: Lippincott Williams & Wilkins

Published: 2016-03-03

Total Pages: 400

ISBN-13: 1496325389

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Lippincott Fast Facts for NCLEX-RN, 2nd edition is a quick and easy review for nursing students to prepare for the licensing examination. Thousands of facts in this resource cover all aspects of nursing care. Each up-to-date fact has been thoroughly reviewed for validity, conciseness, and alignment with the 2016 NCSBN NCLEX-RN test plan. Content, features, and functionality of the resource are aligned with PassPoint RN, making this an ideal print-electronic study package.

Myasthenia Gravis and Myasthenic Disorders

Myasthenia Gravis and Myasthenic Disorders PDF

Author: Andrew G. Engel

Publisher: OUP USA

Published: 2012-04-03

Total Pages: 305

ISBN-13: 019973867X

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Myasthenia Gravis and Myasthenic Disorders, Second Edition is a thoroughly re-written and updated version of the highly successful first edition published in 1999. Comprehensively written by leaders at the forefront of research, not to mention thoroughly referenced throughout and gorgeously illustrated, this new edition of the classic 1999 text will cement its place as the text on Myasthenia Gravis and related disorders for years to come.

Neuromuscular Disorders in Clinical Practice

Neuromuscular Disorders in Clinical Practice PDF

Author: Bashar Katirji

Publisher: Springer Science & Business Media

Published: 2013-10-11

Total Pages: 1565

ISBN-13: 1461465672

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Comprehensive, thoroughly updated, and expanded, Neuromuscular Disorders in Clinical Practice, Second Edition encompasses all disorders of the peripheral nervous system, covering all aspects of neuromuscular diseases from diagnosis to treatment. Mirroring the first book, this two-volume edition is divided into two parts. Part one discusses the approach to neuromuscular disorders, covering principles and basics, neuromuscular investigations, and assessment and treatment of neurological disorders. Part two then addresses the complete range of specific neuromuscular diseases: neuronopathies, peripheral neuropathies, neuromuscular junction disorders, muscle ion channel disorders, myopathies, and miscellaneous neuromuscular disorders and syndromes. Neuromuscular Disorders in Clinical Practice, Second Edition is intended to serve as a comprehensive text for both novice and experienced practitioners. General neurologists as well as specialists in neuromuscular medicine and trainees in neuromuscular medicine, clinical neurophysiology and electromyography should find this book inclusive, comprehensive, practical and highly clinically focused. Additionally, specialists in physical medicine and rehabilitation, rheumatology, neurosurgery, and orthopedics will find the book of great value in their practice.

Myasthenia Gravis and Related Disorders

Myasthenia Gravis and Related Disorders PDF

Author: Henry J. Kaminski

Publisher: Springer Science & Business Media

Published: 2002-10-03

Total Pages: 397

ISBN-13: 1592593410

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An international panel of expert clinicians and leading scientists comprehensively review the clinical and basic science of this disease and its relatives, including acquired neuromytonia and Lambert-Eaton syndrome. For the clinician, the book describes the wide range of signs and symptoms that make these diseases difficult to diagnose, review in depth the available diagnostic methods and their limitations, offer practical treatment recommendations based on years of experience, and discuss several promising treatments now emerging. For the basic scientist, the text illuminates neuromuscular structure and function, describes in detail the acetylcholine receptor (the central target of pathology in myasthenia gravis), and illuminates the autoimmune pathogenesis.

Neuromuscular Disorders

Neuromuscular Disorders PDF

Author: Satish V. Khadilkar

Publisher: Springer

Published: 2017-12-28

Total Pages: 534

ISBN-13: 9811053618

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This book provides a concise overview of the diagnosis and therapy of a wide variety of neuromuscular disorders, in tabulated form and with illustrative cases. Treating neuromuscular disorders calls for a sound, step-by-step clinical approach based on differential diagnosis and laboratory investigations. Yet to date, there has been no single, compact book that offers all the relevant information related to the management of these disorders. This book fills that gap, presenting the state of the art in the field and addressing practical problems together with their solutions. Each chapter covers disorder characteristics, clinical differentiating points, relevant investigations and their interpretation, available genetic testing, best management approaches and counselling. Illustrative cases provide valuable insights, while extensive tables and illustrations mean that information can be rapidly found.

Selected Health Conditions and Likelihood of Improvement with Treatment

Selected Health Conditions and Likelihood of Improvement with Treatment PDF

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2020-07-12

Total Pages: 319

ISBN-13: 0309670950

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The Social Security Administration (SSA) administers two programs that provide disability benefits: the Social Security Disability Insurance (SSDI) program and the Supplemental Security Income (SSI) program. SSDI provides disability benefits to people (under the full retirement age) who are no longer able to work because of a disabling medical condition. SSI provides income assistance for disabled, blind, and aged people who have limited income and resources regardless of their prior participation in the labor force. Both programs share a common disability determination process administered by SSA and state agencies as well as a common definition of disability for adults: "the inability to engage in any substantial gainful activity by reason of any medically determinable physical or mental impairment which can be expected to result in death or which has lasted or can be expected to last for a continuous period of not less than 12 months." Disabled workers might receive either SSDI benefits or SSI payments, or both, depending on their recent work history and current income and assets. Disabled workers might also receive benefits from other public programs such as workers' compensation, which insures against work-related illness or injuries occurring on the job, but those other programs have their own definitions and eligibility criteria. Selected Health Conditions and Likelihood of Improvement with Treatment identifies and defines the professionally accepted, standard measurements of outcomes improvement for medical conditions. This report also identifies specific, long-lasting medical conditions for adults in the categories of mental health disorders, cancers, and musculoskeletal disorders. Specifically, these conditions are disabling for a length of time, but typically don't result in permanently disabling limitations; are responsive to treatment; and after a specific length of time of treatment, improve to the point at which the conditions are no longer disabling.

Electrodiagnosis in Diseases of Nerve and Muscle

Electrodiagnosis in Diseases of Nerve and Muscle PDF

Author: Jun Kimura

Publisher: Oxford University Press

Published: 2013-10

Total Pages: 1177

ISBN-13: 0199738688

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Intended for clinicians who perform electrodiagnostic procedures as an extension of their clinical examination, and for neurologists and physiatrists who are interested in neuromuscular disorders and noninvasive electrodiagnostic methods, particularly those practicing electromyography (EMG) this book provides a comprehensive review of most peripheral nerve and muscle diseases, including specific techniques and locations for performing each test.

Autoantibodies

Autoantibodies PDF

Author: Yehuda Shoenfeld

Publisher: Newnes

Published: 2013-11-26

Total Pages: 917

ISBN-13: 0444593772

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Autoimmune diseases are characterized by the occurrence of antibodies reacting with self-constituents of the body. The fully updated third edition of Autoantibodies is an in-depth review of the main autoantibodies identified up to now, with particular emphasis on those that display a diagnostic or prognostic clinical value. The new edition covers recent scientific advances, diagnostic techniques, and therapeutic technologies. Each chapter is focused on a single family of autoantibodies. This important reference contains historical notes, definitions, origins and sources of antigens recognized genetic associations, mediated pathogenic mechanisms, methods of detection, as well as clinical utility (disease prevalence and association, diagnostic value, sensitivity and specificity, prognostic value). This is an ideal reference for anyone involved in the field of autoimmune diseases. Presents all known, important autoantibodies in a single source, focusing on the antibodies needed for autoimmune disorder diagnosis Includes clinical applications for each autoantibody along with general information Organized by disease and disorder type, by autoantibody family, and completely cross-referenced