Experimental Developmental Biology

Experimental Developmental Biology PDF

Author: Laura R. Keller

Publisher: Academic Press

Published: 1999

Total Pages: 130

ISBN-13: 9780124039704

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This work is designed for use as a lab manual in college-level courses in developmental biology or animal development. In each exercise, students examine gametes and developing embryos of a single species, and also perform several experiments to probe its developmental process.

Experimental Design for Biologists

Experimental Design for Biologists PDF

Author: David J. Glass

Publisher: CSHL Press

Published: 2007

Total Pages: 211

ISBN-13: 0879697350

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The effective design of scientific experiments is critical to success, yet graduate students receive very little formal training in how to do it. Based on a well-received course taught by the author, Experimental Design for Biologistsfills this gap. Experimental Design for Biologistsexplains how to establish the framework for an experimental project, how to set up a system, design experiments within that system, and how to determine and use the correct set of controls. Separate chapters are devoted to negative controls, positive controls, and other categories of controls that are perhaps less recognized, such as “assumption controls†and “experimentalist controls†. Furthermore, there are sections on establishing the experimental system, which include performing critical “system controls†. Should all experimental plans be hypothesis-driven? Is a question/answer approach more appropriate? What was the hypothesis behind the Human Genome Project? What color is the sky? How does one get to Carnegie Hall? The answers to these kinds of questions can be found in Experimental Design for Biologists. Written in an engaging manner, the book provides compelling lessons in framing an experimental question, establishing a validated system to answer the question, and deriving verifiable models from experimental data. Experimental Design for Biologistsis an essential source of theory and practical guidance in designing a research plan.

Key Experiments in Practical Developmental Biology

Key Experiments in Practical Developmental Biology PDF

Author: Manuel Marí-Beffa

Publisher: Cambridge University Press

Published: 2005-03-24

Total Pages: 412

ISBN-13: 9780521833158

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Originally published in 2005, this unique resource presents 27 easy-to-follow laboratory exercises for use in student practical classes in developmental biology. These experiments provide key insights into developmental questions, and many of them are described by the leaders in the field who carried out the original research. This book intends to bridge the gap between experimental work and the laboratory classes taken at the undergraduate and post-graduate levels. All chapters follow the same format, taking the students from materials and methods, through results and discussion, so that they learn the underlying rationale and analysis employed in the research. The book will be an invaluable resource for graduate students and instructors teaching practical developmental biology courses. Chapters include teaching concepts, discussion of the degree of difficulty of each experiment, potential sources of failure, as well as the time required for each experiment to be carried out in a class with students.

Experiments in Molecular Biology

Experiments in Molecular Biology PDF

Author: Robert J. Slater

Publisher: Springer Science & Business Media

Published: 2008-02-07

Total Pages: 385

ISBN-13: 1603274057

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Research in the field of molecular biology has progressed at a fascinating rate in recent years. Much of this progress results from the development of new laboratory techniques that allow very precise fractionation and analysis of nucleic acids and proteins, as well as the construction of recom binant DNA molecules that can then be cloned and expressed in host cells. Progress has been so rapid that there has been a shortfall in the training of appropriately qualified staff. Many existing laboratory workers require retraining, and many educational institutions have had difficulty incor porating the new molecular biology techniques into their teaching programs. Although there are several manuals currently available that describe laboratory techniques in molecular biology, they are principally written for the indivi dual research worker and are not intended for use in the design of practical classes for students. The aim of this book is to provide just such a series of pro tocols for the teaching of practical molecular biology. The idea arose following the success of several Workshops in Molecular Biology, organized and taught by staff in the Biol ogy Department of the Hatfield Polytechnic. Gradually, the protocols used in the workshops have been incorporated into the Hatfield undergraduate and postgraduate teaching pro grams and have now been collected together to form a book.

Developmental Biology

Developmental Biology PDF

Author: Mary S. Tyler

Publisher: Sinauer Associates, Incorporated

Published: 2000

Total Pages: 0

ISBN-13: 9780878938438

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Developmental Biology: A Guide for Experimental Study, Second Edition is a laboratory manual for college-level courses in developmental biology. It teaches students to work as independent investigators on problems in development, and provides extensive background information and instructions for each experiment. It emphasizes the study of living material, intermixing developmental anatomy in an enjoyable balance, and allows students to make choices in their work. The manual contains challenging experiments requiring minimal equipment that are suitable for both large and small classes. Recipes for solutions, annotated bibliographies, and lists of scientific suppliers are also included.

Scientific Frontiers in Developmental Toxicology and Risk Assessment

Scientific Frontiers in Developmental Toxicology and Risk Assessment PDF

Author: National Research Council

Publisher: National Academies Press

Published: 2000-12-21

Total Pages: 348

ISBN-13: 0309070864

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Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.

Landmarks in Developmental Biology 1883–1924

Landmarks in Developmental Biology 1883–1924 PDF

Author: Klaus Sander

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 119

ISBN-13: 3642604927

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Developmental biology took shape between 1880 and the 1920s Basic concepts like the developmental role of chromosomes and the germ plasm (today's genome), self differentiation, embryonic regulation and induction, gradients and organizers hail from that period; indeed, the discipline was defined as a whole by the programmatic writings of Wilhelm Roux as early as 1889. The present essays cover the period up to the Nobel prize-winning work of Hans Spemann and Hilde Mangold. They were originally published in Roux's Archives of Developmental Biology, from Vol. 200 onward to the journal's centennial issues in 1995/96. The essays aim at introducing current adepts of developmental biology to observations and experiments that have lead their predecessors towards basic concepts still influential today.

Laboratory Exercises in Developmental Biology

Laboratory Exercises in Developmental Biology PDF

Author: Yolanda P. Cruz

Publisher: Academic Press

Published: 2012-12-02

Total Pages: 254

ISBN-13: 0323137776

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This intensive manual provides students with valuable information and insights into animal development at the organismal, cellular, and subcellular levels. The book uses both descriptive and investigative approaches that emphasize techniques, key experiments, and data analysis. Provides a broad introductory view of developmental systems Teaches both classical embryology and modern experimental approaches Contains seventeen laboratory exercises, written in step-by-step style Organized with additional notes to students and preparators Lists questions and references for each exercise Special chapters give introductions to the scientific process, use of the microscope, and the writing of scientific papers Illustrated with detailed line drawings