Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA

Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA PDF

Author: Stephen J. Peroutka

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 252

ISBN-13: 1461314852

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The variety of viewpoints expressed in this book illustrate the many contro versies surrounding MDMA [1]. On the one hand, the proponents ofMDMA use believe this agent offers a unique psychoactive effect that may have important clinical applications, especially in the field of psychotherapy. On the other hand, the scientific data concerning the neurotoxic effects of the drug are unequivocal. The most striking feature of the human information of MDMA is the paucity of data that has been generated on the drug since it was patented in 1914. As pointed out by Beck (Chapter 6) and others, a clear need exists for better epidemiological and clinical data on MDMA. In the absence of such data, arguments both for and against the cotinued use ofMDMA with humans will be difficult to support. Unfortunately, the currently available data must be used to develop rational policies for potential human users of MDMA. At the present time, there are no data indicating that recreational doses of MDMA permanently damage the human brain. Nonetheless, based on a review of the contents of this book as well as on informal discussions with approximately 200 recreational users of MDMA, the following personal observations suggest that MDMA is radically different from other recreational drugs.

The Love Drug

The Love Drug PDF

Author: Richard S. Cohen

Publisher: Routledge

Published: 1998

Total Pages: 200

ISBN-13:

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Cohen, a researcher whose work on MDMA has been published in several scholarly journals, gives a balanced and impartial view of the drug's past and present history, covering the structural significance, legal controversy, and adverse reactions surrounding it. Accessible to general readers and partiers as well as researchers, educators, and medical professionals. Paper edition (unseen), $19.95. Annotation copyrighted by Book News, Inc., Portland, OR

Ecstasy

Ecstasy PDF

Author: Eisner

Publisher: Ronin Publishing

Published: 2013-01-09

Total Pages: 260

ISBN-13: 1579511457

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The history of ecstasy, its discovery and use and social implications.

Ecstasy

Ecstasy PDF

Author: Alan Philmann

Publisher: Createspace Independent Publishing Platform

Published: 2016-09-11

Total Pages: 64

ISBN-13: 9781537614656

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Ecstasy is an extremely popular drug among youth, it is extremely is easy to get, and it is not complicated to make. Ecstasy use and the manufacture of it are illegal, but there are a couple of good reasons to synthesize your own MDMA or MDA. The use of ecstasy, specifically in high quantities, can lead to neurotoxicity and memory deficits. Most ecstasy users are polydrug users, so the drug is not typically abused. This book discusses the physiological effects of the drug, how the demographics of the drug's use have changed, and how to produce ecstasy. Despite being made illegal in the 1970s by most Western governments, ecstasy still remains an extremely popular drug today, and it is currently be used in laboratory settings with other psychoactive drugs in conjunction with cognitive therapy to treat individuals suffering from PTSD.

Pursuit of Ecstasy

Pursuit of Ecstasy PDF

Author: Jerome Beck

Publisher: SUNY Press

Published: 1994-01-01

Total Pages: 258

ISBN-13: 9780791418178

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The authors have produced the first "on the ground" study (not just clinical or chemical) of MDMA (3, 4-methylenedioxymethamphetamine), or "ecstasy" as it is frequently designated. A psychoactive substance related to both the amphetamines and mescaline, MDMA has become popular in recent years as one of the new "designer" drugs. First used in therapeutic treatment, its recreational or street use has increased in recent years. The authors track the efforts (with psychiatrists and researchers in opposition) of the DEA to ban the drug.

Pharmacology and Abuse of Cocaine, Amphetamines, Ecstasy and Related Designer Drugs

Pharmacology and Abuse of Cocaine, Amphetamines, Ecstasy and Related Designer Drugs PDF

Author: Enno Freye

Publisher: Springer Science & Business Media

Published: 2009-09-21

Total Pages: 286

ISBN-13: 9048124484

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Finally - a book that covers all aspects of the illicit use of cocaine, amphetamines, ecstasy and/or designer drugs such as GHB, written by two experts in their field. The use of these drugs remains a continuous threat in health and medical care delivery, and this book will be an essential asset to the physician who may have to face the evaluation of patients whose use of these drugs compromises an effective treatment plan for other health issues. The book has been conceived to fill the void in existing physician reference materials, and provides a comprehensive review of the theoretical knowledge and scope of pharmacotherapy in individuals who are hooked on a psychoactive substance. While detailed scientific information is obtainable in other major articles, the book's straightforward format and style, along with its illustrations, will make for easy reading as emphasis is put on information specifically related to drugs that occur most abused in today’s society. The information provided is based on clinical practice rather than pure experimental data, which will give the physician more effective tools useful in their daily practice. Many mechanisms of action of abuse are described in detail and references are provided to direct the reader to further sources for additional information. As a special feature, the book incorporates uncluttered tables and charts, which result in immediate clarification of the mode of action on the central nervous system and the reason for misuse, thus avoiding usual long and fatiguing text in common reference books. The book aims to give the reader a clear and concise plan on what to do when being faced with an overdose situation. A well-organized Table of Contents rapidly leads the reader from general pharmacological issues to the specific overdose syndrome and its management. Additionally, significant emphasis is placed on the practical do's and don’ts for physicians, with special reference to the predictive signs of aberrant drug-related behavior and the identification of the drug diverter by using urine drug screening.

The History of MDMA

The History of MDMA PDF

Author: Torsten Passie

Publisher: Oxford University Press

Published: 2023-05-31

Total Pages: 305

ISBN-13: 0192637274

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As recent statistics show, more than 100 million people on the planet have used MDMA. After cannabis, it is the second most used drug worldwide. Yet there are many misconceptions surrounding the drug, which have affected attempts to use it as a legitimate and highly effective therapeutic aid. Despite the enormous extent of its use, and abuse, MDMA produced neither a large number of medical complications nor social harm on a larger scale, and has very limited addictive potential. In The History of MDMA, Torsten Passie aims to explore a deeper and more differentiated understanding of MDMA and its history. He has conducted personal interviews with most of the people significant in the history of MDMA and provides a lot of new material to present the first comprehensive overview of the history of MDMA in Europe and the U.S. This not just as it is perceived in the public mind, but also in terms of its history as an underground drug, the research into it, political responses to it, its spread, and its medical use. Passie brings these multiple narratives and levels of its history and their complex interactions together in order to make this book an essential reading for anyone interested in the topic.

Affecting Chemicals

Affecting Chemicals PDF

Author: Katherine M. Hendy

Publisher:

Published: 2015

Total Pages: 96

ISBN-13:

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This dissertation ethnographically follows the efforts of researchers to develop MDMA (Ecstasy) as a prescription pharmaceutical. In the 1970's MDMA became popular among psychedelic therapists as a legal alternative to banned substances like LSD and psilocybin. However, legal MDMA-assisted therapy came to a halt in 1985 when the Drug Enforcement Agency (DEA)--reacting to recreational use of MDMA in nightclubs--classified the drug as a Schedule 1 substance--which has no therapeutic application. In the decades following, activists, therapists and researchers have organized clinical trials with MDMA in order to contest the scheduling. The dissertation is based upon in depth ethnographic fieldwork with the Multidisciplinary Association for Psychedelic Studies (MAPS), which has sponsored an international clinical trial program on MDMA-assisted therapy. If successful, these studies will provide the basis for the organization to petition the Food and Drug Administration to approve a novel pharmaceutical treatment. This dissertation examines the ways that various practices of experimentation grant robustness to the chemical, the body, and even experience. The shift to epistemological practice that characterizes this work as a whole is an effort to avoid the constructivist bind by focusing not on what MDMA is or is not, or what it does or does not do, or when it is or is not agentive, but rather how it is apprehended. At several junctures, I argue that the chemical cannot speak for its own identity, but rather requires documentary, regulatory and experimental structures to guarantee it. The focus on practice in my dissertation allows MDMA's status to remain fraught and allows central tensions to manifest--such as the distinction between MDMA and Ecstasy, which is central to MAPS clinical trial program. I argue that understanding the political work of these trials requires close attention to the minute practices of experimentation at work in clinical research.

Ketamine

Ketamine PDF

Author: David T. Yew

Publisher: CRC Press

Published: 2015-03-16

Total Pages: 406

ISBN-13: 1466583401

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Increasing use of ketamine as a recreational drug in Asia, Europe, and America is a great burden on society at large, leading to aspirational strain, unemployment, and crime. These societal effects have led to growing interest among researchers and clinicians in ketamine's effects on various systems of the body. Ketamine: Use and Abuse reviews the