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Drug Hypersensitivity

Author: Werner J. Pichler

Publisher: Karger Medical and Scientific Publishers

Published: 2007-01-01

Total Pages: 440

ISBN-13: 3805582692

Approaches the phenomenon of drug hypersensitivity in a comprehensive manner. Besides epidemiological aspects, it addresses the immunological mechanisms underlying these complicated reactions which go far beyond the IgE-mediated drug allergies also considered in this book. The book also covers clinical manifestations and new diagnostic methods, and introduces some recetly established animal models. Many topics are treated from multiple perspectives, and the 33 chapters are thoroughly cross-referenced.

Drug Hypersensitivity

Author: Werner J. Pichler

Publisher:

Published: 2010

Total Pages: 0

ISBN-13: 9781437724646

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This issue of the Medical Clinics of North America brings the internist up to date on the latest approaches to drug hypersensitivity. Acute symptoms and reactions such as urticaria, angioedema, anaphylaxis, anaphylactic shock are covered. Delayed symptoms such as MPE, SDRIFE, delayed urticaria, vasculitis, Stevens-Johnson Syndrome, toxic epidermal necrolysis, AGEP, and DRESS/D(i)HS are also covered. Complex clinical pictures are explored, including the side effects to biologics, anticoagulation (including HIT), and cytostatic drugs (such asoxaliplatin, cisplatin, paclitaxel, and others). Other topics include perioperative anaphylaxis, betalactam hypersensitivity, and NSAID intolerance.

Drug Hypersensitivity

Author: Werner J. Pichler

Publisher: Clinics: Internal Medicine

Published: 2009

Total Pages: 0

ISBN-13: 9781437712292

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From the Publisher: This issue of the Medical Clinics of North America brings the internist up to date on the latest approaches to drug hypersensitivity. Acute symptoms and reactions such as urticaria, angioedema, anaphylaxis, anaphylactic shock are covered. Delayed symptoms such as MPE, SDRIFE, delayed urticaria, vasculitis, Stevens-Johnson Syndrome, toxic epidermal necrolysis, AGEP, and DRESS/D(i)HS are also covered. Complex clinical pictures are explored, including the side effects to biologics, anticoagulation (including HIT), and cytostatic drugs (such asoxaliplatin, cisplatin, paclitaxel, and others). Other topics include perioperative anaphylaxis, betalactam hypersensitivity, and NSAID intolerance.

Drug Allergy Testing

Author: David Khan

Publisher: Elsevier Health Sciences

Published: 2017-07-05

Total Pages: 250

ISBN-13: 0323497071

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With a focus on improving diagnosis and treatment, Drug Allergy Testing is your new go-to resource for understanding various drug allergies and testing methods, the epidemiology of and economic impact of drug allergies, and new drug and allergy developments. Features a wealth of up-to-date information for allergists, immunologists, and primary care physicians who diagnose and treat patients with drug allergies and hypersensitivity. Covers the basics of drug allergy evaluation and management as well as specific drugs including antibiotics, ASA/NSAIDs, chemotherapeutic agents and monoclonal antibodies.

Drug Allergy

Author: Brian A. Baldo

Publisher: Springer

Published: 2016-05-24

Total Pages: 0

ISBN-13: 9781493963904

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The variety of chemically diverse pharmacological agents administered to patients is large and continues to expand and with every new drug released, there is always potential for adverse reactions, some of them allergic. With its roots in immunology and pharmacology, the science of drug allergy is becoming better understood and applied as its importance is increasingly recognized throughout the many branches of medicine. Drug Allergy: Clinical Aspects, Diagnosis, Mechanisms, Structure-Activity Relationships sheds new light on this field. Comprehensive in design, this authoritative title identifies the most important culprit drugs implicated in immediate and delayed drug hypersensitivities and offers up-to-date information on classifications, diagnoses, underlying mechanisms and structure-activity relationships. Chapters dealing with the molecular and cellular mechanisms of drug hypersensitivities, non-immune-mediated sensitivities and diagnostic methods are presented as introductory material for in-depth treatises on the β-lactam antibiotics, other antibiotics and antimicrobials, drugs used in anesthesia and surgery, opioid analgesics, corticosteroids, monoclonal antibodies and other biologics, drugs used in chemotherapy, proton pump inhibitors, iodinated and gadolinium-based contrast media and non-steroidal anti-inflammatory drugs. In addition to being of immense value to clinicians, other health care professionals and researchers, this title will prove invaluable for those taking undergraduate and graduate courses in science and will also serve as a useful text for students of medicine, pharmacy, nursing and dentistry.

Pediatric Allergy: Principles and Practice E-Book

Author: Donald Y. M. Leung

Publisher: Elsevier Health Sciences

Published: 2010-10-13

Total Pages: 705

ISBN-13: 1437737781

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Pediatric Allergy supplies the comprehensive guidance you need to diagnose, manage, and treat virtually any type of allergy seen in children. Drs. Leung, Sampson, Geha, and Szefler present the new full-color second edition, with coverage of the diagnosis and management of anaphylaxis, the immune mechanisms underlying allergic disease, the latest diagnostic tests, and more. Treat the full range of pediatric allergic and immunologic diseases through clinically focused coverage relevant to both allergists and pediatricians. Understand the care and treatment of pediatric patients thanks to clinical pearls discussing the best approaches. Easily refer to appendices that list common food allergies and autoantibodies in autoimmune diseases. Apply the newest diagnostic tests available—for asthma, upper respiratory allergy, and more—and know their benefits and contraindications. Treat the allergy at its source rather than the resulting reactions through an understanding of the immune mechanisms underlying allergic diseases. Get coverage of new research that affects methods of patient treatment and discusses potential reasons for increased allergies in some individuals. Better manage potential anaphylaxis cases through analysis of contributing facts and progression of allergic disease. Effectively control asthma and monitor its progression using the new step-by-step approach. Eliminate difficulty in prescribing antibiotics thanks to coverage of drug allergies and cross-reactivity.

Asthma, Allergic and Immunologic Diseases During Pregnancy

Author: Jennifer A. Namazy

Publisher: Springer

Published: 2018-12-29

Total Pages: 251

ISBN-13: 3030033953

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With insight and research from world-renowned experts, this book provides specific approaches to diagnosis and treatment, addressing pharmacologic and non-pharmacologic management. Specific conditions examined include asthma, rhinitis and sinusitis, anaphylaxis, atopic and contact dermatitis, urticaria and angioedema, hereditary angioedema, drug allergies, and primary immune deficiency. An overview of obstetric management of the high risk asthmatic and allergic patient is provided, and the book concludes with a discussion of the prevention of asthma and allergic diseases during childhood.

European Handbook of Dermatological Treatments

Author: Andreas D. Katsambas

Publisher: Springer Science & Business Media

Published: 2013-04-17

Total Pages: 830

ISBN-13: 3662071312

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Dermatology is a specialty in the field of medicine which constantly changes at a vast rate. Alongside technology, new drugs, methods and treatments are continuously developed for the treatment of all common skin diseases. The first edition of the European Handbook of Dermatological Treatments received an overwhelming response from dermatovenereologists all over Europe. Its easy-to-read format, which is also used for this 2nd edition, is aimed at helping the physician to obtain comprehensive information at a glance. The three main sections listed alphabetically define the different diseases, the drugs available and the various methods of treatment used in dermatological practice. Each chapter begins with a brief section of the aetiology and pathogenesis of the skin disease, and leads into the description of the clinical characteristics, the diagnosis and the differential diagnosis. Followed by a detailed discussion on treatment methods, alternative methods are covered as well. Each section ends with a reference list for further reading. This new edition provides an excellent update including the newest developments of drugs, methods and treatments in dermatological practice, maintaining the clear structure and well-proven format. It is a very comprehensive and practical guide and should not be missed by those treating patients with skin diseases.

Dermatology Made Easy

Author: Amanda Oakley

Publisher: Scion Publishing Ltd

Published: 2017-05-06

Total Pages: 438

ISBN-13: 1911510118

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A concise overview of the common dermatological conditions most likely to present in general medicine From reviews: "... a perfect solution to the constant struggle that dermatology diagnosis presents to primary care physicians and other providers... This well-formatted book covers a vast array of topics ranging from common to rare skin disorders. The pictures are immensely helpful in the understanding of various skin rashes...." Fam Med 2019;51(5):451–452. “... easy to read and informative. One cannot emphasise enough the quality and comprehensive nature of the photographic content.... As someone who was interested in dermatology even as a medical student my only regret is that this book was not around when I was a student as it would have very adequately guided me into my beloved subspecialty.” Ulster Med J 2017;86(3):1–1. “The introduction outlines dermatological conditions by symptom, morphology and body site, providing an excellent index prior to delving into greater detail in the following chapters. The logical approach and level of detail make this text perfect for medical students, interns/residents, primary care physicians and other specialists who wish to quickly identify differential diagnoses or refresh their knowledge of dermatological conditions.” A Lecturer in Dermatology Dermatology Made Easy is based on the hugely popular DermNet New Zealand website and is designed to help GPs, medical students and dermatologists diagnose skin conditions with confidence. The book starts by providing a series of comprehensive tables, complete with over 500 thumbnail photos, to aid diagnosis according to symptoms, morphology, or body site. Once you have narrowed down the diagnosis, cross-references then guide you to more detailed descriptions, and another 700 photographs, covering: common infections inflammatory rashes non-inflammatory conditions skin lesions Every section provides consistent information on the disorder: who gets it and what causes it? what are the clinical features and does it cause any complications? how do you diagnose it? how do you treat it and how long does it take to resolve? The book concludes with a comprehensive section on further investigations and treatment options. Dermatology Made Easy combines the essential focus of the Made Easy book series with the authority and knowledge base of DermNet New Zealand’s unparalleled resources. Printed in full colour throughout.

Allergic Reactions to Drugs

Author: Alain L. de Weck

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 771

ISBN-13: 3642690882

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According to most studies, allergic reactions represent 35%-50% of all untoward reactions to drugs, yet the pharmacological literature concerning the clinical aspects, diagnosis, and pathophysiological mechanisms of drug allergy is markedly less extensive than reports dealing with the toxicological or pharmacological effects of drugs. The main reasons for this state of affairs may be on the one hand that until a few years ago the pathophysiological mechanisms of the various types of allergic reactions were not well understood, and on the other hand that objective diagnosis of a drug allergy is still fraught with serious difficulties. Drug allergy is still an unpopular topic for most allergologists and pharmacologists; this is reflected by the fact that despite their frequency, allergic reactions to drugs still occupy a relatively small proportion of space in most pharmacology handbooks and in classical books devoted to the side effects of drugs. There has recently been considerable progress in research into the immunologi cal and pathophysiological events occurring in allergic reactions, and on that basis investigations of various drug allergies have also yield~d new objective findings. Consequently, it was natural to attempt a review of the most frequent and important drug allergies in the form of a handbook. We originally intended to present a comprehensive review of all drug allergies, but the realization of this goal soon became more difficult than we had at first imagined.