The Welfare of Laboratory Animals

The Welfare of Laboratory Animals PDF

Author: Eila Kaliste

Publisher: Springer Science & Business Media

Published: 2007-04-18

Total Pages: 351

ISBN-13: 1402022719

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This book examines the general principles of laboratory animal maintenance and experimental use as well as factors that have to be taken into account when good research is done with animals. In addition, it provides species specific coverage, concentrating on the species most used as laboratory animals. The book gives a comprehensive description of the welfare questions considered to be important for each species under laboratory conditions.

Deep Learning and Convolutional Neural Networks for Medical Image Computing

Deep Learning and Convolutional Neural Networks for Medical Image Computing PDF

Author: Le Lu

Publisher: Springer

Published: 2017-07-12

Total Pages: 326

ISBN-13: 331942999X

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This book presents a detailed review of the state of the art in deep learning approaches for semantic object detection and segmentation in medical image computing, and large-scale radiology database mining. A particular focus is placed on the application of convolutional neural networks, with the theory supported by practical examples. Features: highlights how the use of deep neural networks can address new questions and protocols, as well as improve upon existing challenges in medical image computing; discusses the insightful research experience of Dr. Ronald M. Summers; presents a comprehensive review of the latest research and literature; describes a range of different methods that make use of deep learning for object or landmark detection tasks in 2D and 3D medical imaging; examines a varied selection of techniques for semantic segmentation using deep learning principles in medical imaging; introduces a novel approach to interleaved text and image deep mining on a large-scale radiology image database.

Medicines from Animal Cell Culture

Medicines from Animal Cell Culture PDF

Author: Glyn N. Stacey

Publisher: John Wiley & Sons

Published: 2007-06-29

Total Pages: 696

ISBN-13: 9780470723784

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Medicines from Animal Cell Culture focuses on the use of animal cell culture, which has been used to produce human and veterinary vaccines, interferon, monoclonal antibodies and genetically engineered products such as tPA and erythropoietin. It also addresses the recent dramatic expansion in cell-based therapies, including the use of live cells for tissue regeneration and the culture of stem cells. Medicines from Animal Cell Culture: Provides comprehensive descriptions of methods for cell culture and nutrition as well as the technologies for the preservation and characterisation of both the cells and the derived products Describes the preparation of stem cells and others for use in cell-based therapies – an area of burgeoning research Includes experimental examples to indicate expected results Covers regulatory issues from the UK, the EU and the USA and reviews how these are developing around the world Addresses the key issues of standardisation and validation with chapters on GLP and GMP for cell culture processes Delivering insight into the exciting world of biological medicines and directions for further investigation into specific topics, Medicines from Animal Cell Culture is an essential resource for researchers and technicians at all levels using cell culture within the pharmaceutical, biotechnology and biomedical industries. It is of value to laboratory managers in these industries and to all those interested in this topic alike.

Advanced Machine Learning Technologies and Applications

Advanced Machine Learning Technologies and Applications PDF

Author: Aboul Ella Hassanien

Publisher: Springer

Published: 2014-11-04

Total Pages: 542

ISBN-13: 3319134612

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This book constitutes the refereed proceedings of the Second International Conference on Advanced Machine Learning Technologies and Applications, AMLTA 2014, held in Cairo, Egypt, in November 2014. The 49 full papers presented were carefully reviewed and selected from 101 initial submissions. The papers are organized in topical sections on machine learning in Arabic text recognition and assistive technology; recommendation systems for cloud services; machine learning in watermarking/authentication and virtual machines; features extraction and classification; rough/fuzzy sets and applications; fuzzy multi-criteria decision making; Web-based application and case-based reasoning construction; social networks and big data sets.

Shape Analysis in Medical Image Analysis

Shape Analysis in Medical Image Analysis PDF

Author: Shuo Li

Publisher: Springer Science & Business Media

Published: 2014-01-28

Total Pages: 441

ISBN-13: 3319038133

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This book contains thirteen contributions from invited experts of international recognition addressing important issues in shape analysis in medical image analysis, including techniques for image segmentation, registration, modelling and classification and applications in biology, as well as in cardiac, brain, spine, chest, lung and clinical practice. This volume treats topics such as for example, anatomic and functional shape representation and matching; shape-based medical image segmentation; shape registration; statistical shape analysis; shape deformation; shape-based abnormity detection; shape tracking and longitudinal shape analysis; machine learning for shape modeling and analysis; shape-based computer-aided-diagnosis; shape-based medical navigation; benchmark and validation of shape representation, analysis and modeling algorithms. This work will be of interest to researchers, students and manufacturers in the fields of artificial intelligence, bioengineering, biomechanics, computational mechanics, computational vision, computer sciences, human motion, mathematics, medical imaging, medicine, pattern recognition and physics.

Image Analysis and Modeling in Ophthalmology

Image Analysis and Modeling in Ophthalmology PDF

Author: Eddie Y. K. Ng

Publisher: CRC Press

Published: 2014-02-11

Total Pages: 402

ISBN-13: 1466559381

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Digital fundus images can effectively diagnose glaucoma and diabetes retinopathy, while infrared imaging can show changes in the vascular tissues. Likening the eye to the conventional camera, Image Analysis and Modeling in Ophthalmology explores the application of advanced image processing in ocular imaging. This book considers how images can be us

Diabetes and Fundus OCT

Diabetes and Fundus OCT PDF

Author: Ayman S. El-Baz

Publisher: Elsevier

Published: 2020-04-02

Total Pages: 434

ISBN-13: 0128174412

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Diabetes and Fundus OCT brings together a stellar cast of authors who review the computer-aided diagnostic (CAD) systems developed to diagnose non-proliferative diabetic retinopathy in an automated fashion using Fundus and OCTA images. Academic researchers, bioengineers, new investigators and students interested in diabetes and retinopathy need an authoritative reference to bring this multidisciplinary field together to help reduce the amount of time spent on source-searching and instead focus on actual research and the clinical application. This reference depicts the current clinical understanding of diabetic retinopathy, along with the many scientific advances in understanding this condition. As the role of optical coherence tomography (OCT) in the assessment and management of diabetic retinopathy has become significant in understanding the vireo retinal relationships and the internal architecture of the retina, this information is more critical than ever. Includes unique information for academic clinicians, researchers and bioengineers Provides insights needed to understand the imaging modalities involved, the unmet clinical need that is being addressed, and the engineering and technical approaches applied Brings together details on the retinal vasculature in diabetics as imaged by optical coherence tomography angiography and automated detection of retinal disease

Atomic Force Microscopy

Atomic Force Microscopy PDF

Author: Nuno C. Santos

Publisher: Humana Press

Published: 2018-10-30

Total Pages: 372

ISBN-13: 9781493988938

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This book aims to provide examples of applications of atomic force microscopy (AFM) using biological samples, showing different methods for AFM sample preparation, data acquisition and processing, and avoiding technical problems. Divided into two sections, chapters guide readers through image artifacts, process and quantitatively analyze AFM images, lipid bilayers, image DNA-protein complexes, AFM cell topography, single-molecule force spectroscopy, single-molecule dynamic force spectroscopy, fluorescence methodologies, molecular recognition force spectroscopy, biomechanical characterization, AFM-based biosensor setup, and detail how to implement such an in vitro system, which can monitor cardiac electrophysiology, intracellular calcium dynamics, and single cell mechanics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Atomic Force Microscopy: Methods and Protocols is useful for researchers at different stages, from newcomers to experienced users, interested in new AFM applications.