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Difference Unbound

Author: Stamos Metzidakis

Publisher: BRILL

Published: 2012-01-01

Total Pages: 290

ISBN-13: 9004358013

This is the first book to examine the precise relationship between pluralism and the production of Western literature and criticism from the eighteenth century to the present. It underscores the historical rather than exclusively epistemological reasons behind what is here called “the rise of literary pluralism.” This rise entails, on the one hand, the modern day phenomenon of an ever-increasing number of readings of both canonical and contemporary works of verbal art; and, on the other, our ever-growing body of literature written with an eye towards different types of characters, situations, forms and styles. Reviewing a wide range of authors and thinkers—from German, French and English Romantics to Anglo-American and European poststructuralist theorists—it shows how and why the current literary emphasis on difference derives from an unquestioned allegiance to the notion of cultural pluralism. While never denying the value of the latter, it seeks instead to analyze the oftentimes unquestioned implications of this historically-situated belief within the specific realm of literary studies.

The Sovereign-Bank Nexus in Emerging Markets in the Wake of the COVID-19 Pandemic

Author: Andrea Deghi

Publisher: International Monetary Fund

Published: 2022-11-11

Total Pages: 54

ISBN-13:

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The COVID-19 pandemic has brought the relationship between sovereigns and banks—the so-called sovereign-bank nexus—in emerging market economies to the fore as bank holdings of domestic sovereign debt have surged. This paper examines the empirical relevance of this nexus to assess how it could amplify macro-financial stability risks. The findings show that an increase in sovereign credit risk can adversely affect banks’ balance sheets and credit supply, especially in countries with less-well-capitalized banking systems. Sovereign distress can also impact banks indirectly through the nonfinancial corporate sector by constraining their funding and reducing their capital expenditure. Notably, the effects on banks and corporates are strongly nonlinear in the size of the sovereign distress.

Annual Reports in Medicinal Chemistry

Author:

Publisher: Elsevier

Published: 2011-08-09

Total Pages: 646

ISBN-13: 9780080554877

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Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. * Critical reviews of the previous year’s literature in many topics of interest to medicinal chemists * Highlights major developments in medicinal chemistry * Includes a comprehensive set of cumulative indexes to easily locate topics in all published volumes

Report

Author: Michigan State University. Library

Publisher:

Published: 1880

Total Pages: 64

ISBN-13:

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Neglected Factors in Pharmacology and Neuroscience Research

Author: V. Claassen

Publisher: Elsevier

Published: 2013-10-22

Total Pages: 501

ISBN-13: 1483145891

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Techniques in the Behavioral and Neural Sciences, Volume 12: Neglected Factors in Pharmacology and Neuroscience Research: Biopharmaceutics, Animal Characteristics, Maintenance, Testing Conditions can be used as reference in the improvement of test designs for biochemists and physiologists in the control of test conditions. The book is divided into five sections. The introduction deals with the uncertainty of animal characteristics and test conditions as hindrances to the development of general insight into biological regulatory mechanism. The first section discusses biopharmaceutics — the interaction of drugs when interacting with molecules or enzymes in sufficient concentration at a specific site of action. The second section reviews animal characteristics in terms of strain differences, sex differences, and changes during development and aging of the subject. The third section discusses the maintenance of experimental animals such as housing conditions, food composition, and water intake as these kinds of environmental factors may shape the phenotype and responsiveness of the experimental animal. The fourth section explains the testing conditions such as metabolic effects and drug interactions, anesthesia, stress, and even the effects on circadian rhythms. The last section is a discussion on the importance of experimental results. This section covers internal and external validities and statistical inference. The author concludes that the design of any experiment should include a power analysis so that reliable and valuable conclusions can follow. Biochemists, physiologists, pharmacokineticists, toxicologists, chemical researchers, and others for whom drugs are their main focus of study will find this book valuable.

Drug Interactions in Infectious Diseases: Antimicrobial Drug Interactions

Author: Manjunath P. Pai

Publisher: Springer

Published: 2018-03-19

Total Pages: 565

ISBN-13: 3319724169

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The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”. This volume, “Antimicrobial Drug Interactions,” delivers a quick clinical resource that distills relevant drug interactions by antimicrobial drug class. The book provides informative tables on specific drug-drug interactions that include the degree and severity of the expected interaction. A mechanistic basis for drug-drug interactions is also provided to link observed interactions to pharmacologic characteristics of key drug classes. This complete resource is organized by major antibacterial, antimycobacterial, antiviral, antifungal, antimalarial, and antiprotozoal class. In line with current innovations in antimicrobial drug development, a distinct chapter on the pharmacologic management of drug interactions in hepatitis B virus (HBV) and hepatitis C virus (HCV)-related infections is included. Two new chapters are dedicated to the management of human immunodeficiency virus (HIV) drug-drug interactions given the breadth of antiretroviral class-specific effects. This comprehensive review of known drug interactions and strategies to manage them is an invaluable resource to all health care practitioners.