Developmental Immunology

Developmental Immunology PDF

Author: Edwin Lowell Cooper

Publisher:

Published: 1993

Total Pages: 504

ISBN-13:

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This timely, comprehensive volume draws on recent advances in molecular, cellular and organismal biology to provide a detailed analysis of the phylogeny and ontogeny of the immune system. This first book to provide broad coverage of this field gives a clear description of cellular and molecular interactions in the development of immune function. Although most of this work is based on studies in vertebrates, the intriguing observations of cytokine-like molecules in invertebrates are discussed. In a final section, the contributors deal with abnormalities in the development and regulation of the immune system, including primary immunodeficiency diseases, and with the normal aging of the immune system. Throughout the book, an effort has been made to compare and integrate information from studies in diverse systems, and to discuss the limitations of such comparisons. This work will be of special interest to immunologists and theoretical, cell and developmental biologisis, and much of the book will be useful to physicians working in pediatrics, internal medicine and reproductive medicine.

Immunology and Developmental Biology of the Chicken

Immunology and Developmental Biology of the Chicken PDF

Author: Olli Vainio

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 281

ISBN-13: 3642800572

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Books on both chicken immunology and developmental biology are rare. This one, however, summarizes all aspects of both areas and therefore represents a valuable compendium for experienced researchers as well as for all newcomers to the field. Following a lengthy discussion of the origin of hemopoietic cells, regulatory elements for the differentiation of these cells and B and T cell lymphopoiesis, the book goes on to describe the generation of transgenic chickens as well as an additional basic feature in embryogenesis: the positioning of organ anlage, e.g. the limb bud. To round off, a valuable compilation of monoclonal antibodies further enhances the practical usefulness of this important book.

Janeway's Immunobiology

Janeway's Immunobiology PDF

Author: Kenneth Murphy

Publisher: Garland Science

Published: 2010-06-22

Total Pages:

ISBN-13: 9780815344575

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The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Aspects of Developmental and Comparative Immunology

Aspects of Developmental and Comparative Immunology PDF

Author: J. B. Solomon

Publisher: Elsevier

Published: 2014-05-09

Total Pages: 591

ISBN-13: 1483189716

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Aspects of Developmental and Comparative Immunology contains the proceedings of the 1st Congress of Developmental and Comparative Immunology, held from July 27 to August 1, 1980 in Aberdeen, Scotland. The papers explore various aspects of developmental and comparative immunology and cover topics ranging from the major histocompatibility complex (MHC) and membrane immunoglobulins to idiotypes and diversity, comparative ontogeny, and evolution of lymphoid organ function. Comprised of 105 chapters, this volume begins with an overview of how the host immune system utilizes polymorphic MHC antigens as the principal tool for pseudo-self versus true self distinction. The reader is then introduced to the immunology of earthworms, membrane immunoglobulins, idiotypes, and diversity. Subsequent chapters focus on the evolution of lymphoid organs in vertebrates; differentiation clocks in comparative immunology of mammals and birds; immunorecognition in invertebrates such as insects and gastropods; and the phylogeny of leucocytes in vertebrates and invertebrates. The remaining sections deal with stem cells, immune responses of gut-associated lymphoepithelial tissue, and the ontogeny of resistance to infection as well as the ontogeny of killer cells. Finally, the immunology of fish, amphibians, reptiles, chickens, and mammals is examined. This monograph will be of interest to immunobiologists.

Developmental Immunotoxicology

Developmental Immunotoxicology PDF

Author: Steven D. Holladay

Publisher: CRC Press

Published: 2004-11-15

Total Pages: 386

ISBN-13: 9781420024036

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Despite rapidly increasing interest in developmental immunotoxicology, there is not yet a textbook focused on this hot area of research. Developmental Immunotoxicology fills the void with overviews of immune system development in experimental animal and human models, and discusses the complex issues related to the evolution of developmental immunology and risk assessment. This text describes different models used to study developmental immunotoxicology and examples of specific developmental immunotoxic agents, including therapeutics. The text concludes with several chapters that describe the role of neuroimmune interactions as they relate to developmental immunotoxicology. Using a didactic approach, Developmental Immunotoxicology provides an explanatory overview of this cutting-edge field for toxicologists, immunologists, and developmental biologists. It provides a lucid account of this area of research-proposing answers to some questions and stimulating debate on those questions yet to be addressed by the research community.

Advances in Comparative Immunology

Advances in Comparative Immunology PDF

Author: Edwin L. Cooper

Publisher: Springer

Published: 2018-08-07

Total Pages: 1048

ISBN-13: 3319767682

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Immunologists, perhaps understandably, most often concentrate on the human immune system, an anthropocentric focus that has resulted in a dearth of information about the immune function of all other species within the animal kingdom. However, knowledge of animal immune function could help not only to better understand human immunology, but perhaps more importantly, it could help to treat and avoid the blights that affect animals, which consequently affect humans. Take for example the mass death of honeybees in recent years – their demise, resulting in much less pollination, poses a serious threat to numerous crops, and thus the food supply. There is a similar disappearance of frogs internationally, signaling ecological problems, among them fungal infections. This book aims to fill this void by describing and discussing what is known about non-human immunology. It covers various major animal phyla, its chapters organized in a progression from the simplest unicellular organisms to the most complex vertebrates, mammals. Chapters are written by experts, covering the latest findings and new research being conducted about each phylum. Edwin L. Cooper is a Distinguished Professor in the Laboratory of Comparative Immunology, Department of Neurobiology at UCLA’s David Geffen School of Medicine.

Developmental Biology of Peripheral Lymphoid Organs

Developmental Biology of Peripheral Lymphoid Organs PDF

Author: Peter Balogh

Publisher: Springer Science & Business Media

Published: 2010-11-04

Total Pages: 178

ISBN-13: 3642144292

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The human immune system is a complex network of tissues and organs dispersed throughout the body. Immunology, as one of the most rapidly evolving fields in bio¬medical research, has to date covered the essential cellular and molecular events neces¬sary for immune responses to occur. However, it has paid relatively little attention to important developmental processes underlying the formation of the tissues themselves that carry out immune responses in humans and other mammalians. In contrast to the thymus and bone marrow that are the sole tissues for generating mature leukocytes for antigen recognition and han¬dling in humans and most mammalian species, the peripheral lymphoid tissues where adaptive immune responses are focused display broad tissue distribution and possess diverse archi¬tectural characteristics. These organs develop prior to the individual’s exposure to external antigens, and despite their similar functions, their varied appearances indicate a substantial complexity of tissue ontogeny. This volume presents a comprehensive overview of the developmental features of the major peripheral lymphoid organs, thus examining the connection between immunological functionality and structural characteristics utilizing a developmental approach, for an audience ranging from undergraduate students to senior researchers in immunology, histology and clinical medicine.

Immunity to Change

Immunity to Change PDF

Author: Robert Kegan

Publisher: Harvard Business Press

Published: 2009-02-15

Total Pages: 340

ISBN-13: 1422129470

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Unlock your potential and finally move forward. A recent study showed that when doctors tell heart patients they will die if they don't change their habits, only one in seven will be able to follow through successfully. Desire and motivation aren't enough: even when it's literally a matter of life or death, the ability to change remains maddeningly elusive. Given that the status quo is so potent, how can we change ourselves and our organizations? In Immunity to Change, authors Robert Kegan and Lisa Lahey show how our individual beliefs--along with the collective mind-sets in our organizations--combine to create a natural but powerful immunity to change. By revealing how this mechanism holds us back, Kegan and Lahey give us the keys to unlock our potential and finally move forward. And by pinpointing and uprooting our own immunities to change, we can bring our organizations forward with us. This persuasive and practical book, filled with hands-on diagnostics and compelling case studies, delivers the tools you need to overcome the forces of inertia and transform your life and your work.

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