Aspects of Developmental and Comparative Immunology

Aspects of Developmental and Comparative Immunology PDF

Author: J. B. Solomon

Publisher: Elsevier

Published: 2014-05-09

Total Pages: 591

ISBN-13: 1483189716

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Aspects of Developmental and Comparative Immunology contains the proceedings of the 1st Congress of Developmental and Comparative Immunology, held from July 27 to August 1, 1980 in Aberdeen, Scotland. The papers explore various aspects of developmental and comparative immunology and cover topics ranging from the major histocompatibility complex (MHC) and membrane immunoglobulins to idiotypes and diversity, comparative ontogeny, and evolution of lymphoid organ function. Comprised of 105 chapters, this volume begins with an overview of how the host immune system utilizes polymorphic MHC antigens as the principal tool for pseudo-self versus true self distinction. The reader is then introduced to the immunology of earthworms, membrane immunoglobulins, idiotypes, and diversity. Subsequent chapters focus on the evolution of lymphoid organs in vertebrates; differentiation clocks in comparative immunology of mammals and birds; immunorecognition in invertebrates such as insects and gastropods; and the phylogeny of leucocytes in vertebrates and invertebrates. The remaining sections deal with stem cells, immune responses of gut-associated lymphoepithelial tissue, and the ontogeny of resistance to infection as well as the ontogeny of killer cells. Finally, the immunology of fish, amphibians, reptiles, chickens, and mammals is examined. This monograph will be of interest to immunobiologists.

Developmental Immunology

Developmental Immunology PDF

Author: Edwin Lowell Cooper

Publisher:

Published: 1993

Total Pages: 504

ISBN-13:

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This timely, comprehensive volume draws on recent advances in molecular, cellular and organismal biology to provide a detailed analysis of the phylogeny and ontogeny of the immune system. This first book to provide broad coverage of this field gives a clear description of cellular and molecular interactions in the development of immune function. Although most of this work is based on studies in vertebrates, the intriguing observations of cytokine-like molecules in invertebrates are discussed. In a final section, the contributors deal with abnormalities in the development and regulation of the immune system, including primary immunodeficiency diseases, and with the normal aging of the immune system. Throughout the book, an effort has been made to compare and integrate information from studies in diverse systems, and to discuss the limitations of such comparisons. This work will be of special interest to immunologists and theoretical, cell and developmental biologisis, and much of the book will be useful to physicians working in pediatrics, internal medicine and reproductive medicine.