Degenerate Diffusion Operators Arising in Population Biology (AM-185)

Degenerate Diffusion Operators Arising in Population Biology (AM-185) PDF

Author: Charles L. Epstein

Publisher: Princeton University Press

Published: 2013-04-04

Total Pages: 321

ISBN-13: 1400846102

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This book provides the mathematical foundations for the analysis of a class of degenerate elliptic operators defined on manifolds with corners, which arise in a variety of applications such as population genetics, mathematical finance, and economics. The results discussed in this book prove the uniqueness of the solution to the Martingale problem and therefore the existence of the associated Markov process. Charles Epstein and Rafe Mazzeo use an "integral kernel method" to develop mathematical foundations for the study of such degenerate elliptic operators and the stochastic processes they define. The precise nature of the degeneracies of the principal symbol for these operators leads to solutions of the parabolic and elliptic problems that display novel regularity properties. Dually, the adjoint operator allows for rather dramatic singularities, such as measures supported on high codimensional strata of the boundary. Epstein and Mazzeo establish the uniqueness, existence, and sharp regularity properties for solutions to the homogeneous and inhomogeneous heat equations, as well as a complete analysis of the resolvent operator acting on Hölder spaces. They show that the semigroups defined by these operators have holomorphic extensions to the right half-plane. Epstein and Mazzeo also demonstrate precise asymptotic results for the long-time behavior of solutions to both the forward and backward Kolmogorov equations.

Degenerate Diffusion Operators Arising in Population Biology (AM-185)

Degenerate Diffusion Operators Arising in Population Biology (AM-185) PDF

Author: Charles L. Epstein

Publisher:

Published: 2013

Total Pages: 321

ISBN-13: 9781400847181

DOWNLOAD EBOOK →

This book provides the mathematical foundations for the analysis of a class of degenerate elliptic operators defined on manifolds with corners, which arise in a variety of applications such as population genetics, mathematical finance, and economics. The results discussed in this book prove the uniqueness of the solution to the Martingale problem and therefore the existence of the associated Markov process. Charles Epstein and Rafe Mazzeo use an "integral kernel method" to develop mathematical foundations for the study of such degenerate elliptic operators and the stochastic processes they define. The precise nature of the degeneracies of the principal symbol for these operators leads to solutions of the parabolic and elliptic problems that display novel regularity properties. Dually, the adjoint operator allows for rather dramatic singularities, such as measures supported on high codimensional strata of the boundary. Epstein and Mazzeo establish the uniqueness, existence, and sharp regularity properties for solutions to the homogeneous and inhomogeneous heat equations, as well as a complete analysis of the resolvent operator acting on Hölder spaces. They show that the semigroups defined by these operators have holomorphic extensions to the right half-plane. Epstein and Mazzeo also demonstrate precise asymptotic results for the long-time behavior of solutions to both the forward and backward Kolmogorov equations.

Parabolic Equations in Biology

Parabolic Equations in Biology PDF

Author: Benoît Perthame

Publisher: Springer

Published: 2015-09-09

Total Pages: 199

ISBN-13: 331919500X

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This book presents several fundamental questions in mathematical biology such as Turing instability, pattern formation, reaction-diffusion systems, invasion waves and Fokker-Planck equations. These are classical modeling tools for mathematical biology with applications to ecology and population dynamics, the neurosciences, enzymatic reactions, chemotaxis, invasion waves etc. The book presents these aspects from a mathematical perspective, with the aim of identifying those qualitative properties of the models that are relevant for biological applications. To do so, it uncovers the mechanisms at work behind Turing instability, pattern formation and invasion waves. This involves several mathematical tools, such as stability and instability analysis, blow-up in finite time, asymptotic methods and relative entropy properties. Given the content presented, the book is well suited as a textbook for master-level coursework.

Nonlocal Diffusion Problems

Nonlocal Diffusion Problems PDF

Author: Fuensanta Andreu-Vaillo

Publisher: American Mathematical Soc.

Published: 2010

Total Pages: 274

ISBN-13: 0821852302

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Nonlocal diffusion problems arise in a wide variety of applications, including biology, image processing, particle systems, coagulation models, and mathematical finance. These types of problems are also of great interest for their purely mathematical content. This book presents recent results on nonlocal evolution equations with different boundary conditions, starting with the linear theory and moving to nonlinear cases, including two nonlocal models for the evolution of sandpiles. Both existence and uniqueness of solutions are considered, as well as their asymptotic behaviour. Moreover, the authors present results concerning limits of solutions of the nonlocal equations as a rescaling parameter tends to zero. With these limit procedures the most frequently used diffusion models are recovered: the heat equation, the $p$-Laplacian evolution equation, the porous media equation, the total variation flow, a convection-diffusion equation and the local models for the evolution of sandpiles due to Aronsson-Evans-Wu and Prigozhin. Readers are assumed to be familiar with the basic concepts and techniques of functional analysis and partial differential equations. The text is otherwise self-contained, with the exposition emphasizing an intuitive understanding and results given with full proofs. It is suitable for graduate students or researchers. The authors cover a subject that has received a great deal of attention in recent years. The book is intended as a reference tool for a general audience in analysis and PDEs, including mathematicians, engineers, physicists, biologists, and others interested in nonlocal diffusion problems.

Introduction to the Mathematics of Medical Imaging

Introduction to the Mathematics of Medical Imaging PDF

Author: Charles L. Epstein

Publisher: SIAM

Published: 2008-01-01

Total Pages: 794

ISBN-13: 9780898717792

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At the heart of every medical imaging technology is a sophisticated mathematical model of the measurement process and an algorithm to reconstruct an image from the measured data. This book provides a firm foundation in the mathematical tools used to model the measurements and derive the reconstruction algorithms used in most of these modalities. The text uses X-ray computed tomography (X-ray CT) as a 'pedagogical machine' to illustrate important ideas and its extensive discussion of background material makes the more advanced mathematical topics accessible to people with a less formal mathematical education. This new edition contains a chapter on magnetic resonance imaging (MRI), a revised section on the relationship between the continuum and discrete Fourier transforms, an improved description of the gridding method, and new sections on both Grangreat's formula and noise analysis in MR-imaging. Mathematical concepts are illuminated with over 200 illustrations and numerous exercises.

Control Theory and Systems Biology

Control Theory and Systems Biology PDF

Author: Pablo A. Iglesias

Publisher: MIT Press

Published: 2010

Total Pages: 359

ISBN-13: 0262013347

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A survey of how engineering techniques from control and systems theory can be used to help biologists understand the behavior of cellular systems.

The Analysis of Fractional Differential Equations

The Analysis of Fractional Differential Equations PDF

Author: Kai Diethelm

Publisher: Springer

Published: 2010-08-18

Total Pages: 251

ISBN-13: 3642145744

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Fractional calculus was first developed by pure mathematicians in the middle of the 19th century. Some 100 years later, engineers and physicists have found applications for these concepts in their areas. However there has traditionally been little interaction between these two communities. In particular, typical mathematical works provide extensive findings on aspects with comparatively little significance in applications, and the engineering literature often lacks mathematical detail and precision. This book bridges the gap between the two communities. It concentrates on the class of fractional derivatives most important in applications, the Caputo operators, and provides a self-contained, thorough and mathematically rigorous study of their properties and of the corresponding differential equations. The text is a useful tool for mathematicians and researchers from the applied sciences alike. It can also be used as a basis for teaching graduate courses on fractional differential equations.

Hypocoercivity

Hypocoercivity PDF

Author: CŽdric Villani

Publisher: American Mathematical Soc.

Published: 2009-10-08

Total Pages: 154

ISBN-13: 0821844989

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This memoir attempts at a systematic study of convergence to stationary state for certain classes of degenerate diffusive equations, taking the general form ${\frac{\partial f}{\partial t}}+ L f =0$. The question is whether and how one can overcome the degeneracy by exploiting commutators.

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