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Adverse Cutaneous Drug Eruptions

Author: Lars E. French

Publisher: Karger Medical and Scientific Publishers

Published: 2012

Total Pages: 255

ISBN-13: 3805599706

An indispensable tool for understanding, diagnosing and managing this common clinical problem The skin is one of the most frequently involved organs in adverse drug reactions. Occurring with an incidence of 1-5% for certain types of drugs, cutaneous drug eruptions are mostly benign in nature, and comprise the maculopapular type of eruption and urticaria. However, about one third of them require hospital treatment, leading to a considerable burden for the health care system. In this book, a selected group of experts provide an up-to-date, condensed and clinically relevant overview of the field of cutaneous drug eruptions, ranging from epidemiology and genetic predisposition to available therapeutic measures, including rapid drug desensitization. Reflecting the great progress made in recent years in this field, this publication will be a useful tool for a better understanding, diagnosis and management of cutaneous drug eruptions, not only for general physicians, dermatologists and clinical allergologists, but also for nurses and scientists.

Cutaneous Drug Eruptions

Author: John C. Hall

Publisher: Springer

Published: 2015-08-21

Total Pages: 456

ISBN-13: 1447167295

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The burden of cutaneous drug reactions is significant, in both outpatient and inpatient settings, and can result in morbidity and even mortality. This book is unique in its approach to this problem. This text is divided into basic principles, common drug reactions, skin conditions mimicked by drug reactions, drug reactions to the skin appendages, life-threatening drug reactions, less common drug reactions, and special groupings of drug reactions. For the clinician, the skin can only morphologically react in to many limited ways. This is also true for the pathologist. Combining these two forever linked specialties is a synergistic paradigm that greatly enhances diagnosis, and ultimately therapy, for these pernicious conditions. Drug reactions in the skin remain a common complication of therapy. True incidences of drug reactions are not available. For general discussion, the rule of 3% can be applied with reasonable assuredness. Approximately 3% of all hospitalized patients develop an adverse cutaneous drug reaction. Approximately 3% of these reactions are considered severe. Outpatient data is even more obscure, but at least 3% of dermatology clinic outpatient visits are due to a drug reaction. Cutaneous drug reactions compromise approximately 3% of all drug reactions. Even more challenging is the fact that the most vulnerable populations to drug reactions are increasing and include the elderly patients on prolonged drug therapy, and patients that use multiple drugs at the same time.

Advances in Diagnosis and Management of Cutaneous Adverse Drug Reactions

Author: Neil H. Shear

Publisher: Springer

Published: 2018-10-19

Total Pages: 314

ISBN-13: 9811314896

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This resource guides prescribers, pharmacists, and regulators with an update on the recent expansion of basic and clinical knowledge that forms a framework for understanding cutaneous reactions. This understanding will lead, in turn, to better outcomes and decisions in treatment and management, both in the clinic and in the life cycle of drug development. The skin is a common target for adverse drug events and even mild rashes can be part of life-threatening syndromes. Patients and practitioners often face important decisions about therapy after a drug eruption, including treatment, cross-reactivity with future pharmaceuticals, genetic considerations and dealing with long-term sequelae after a reaction. An international team of experts and leaders in the field share their story and insights into the scientific details and relevant clinical context.

Inpatient Dermatology

Author: Misha Rosenbach

Publisher: Springer

Published: 2018-11-03

Total Pages: 415

ISBN-13: 3319184490

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Inpatient Dermatology is a concise and portable resource that synthesizes the most essential material to help physicians with recognition, differential diagnosis, work-up, and treatment of dermatologic issues in the hospitalized patient. Complete with hundreds of clinical and pathologic images, this volume is both an inpatient dermatology atlas and a practical guide to day-one, initial work-up, and management plan for common and rare skin diseases that occur in the inpatient setting. Each chapter is a bulleted, easy-to-read reference that focuses on one specific inpatient dermatologic condition, with carefully curated clinical photographs and corresponding histopathologic images to aid readers in developing clinical-pathologic correlation for the dermatologic diseases encountered in the hospital. Before each subsection the editors share diagnostic pearls, explaining their approach to these challenging conditions. This book is structured to be useful to physicians, residents, and medical students. It spans dermatology, emergency medicine, internal medicine, infectious disease, and rheumatology. Inpatient Dermatology is the go-to guide for hospital-based skin diseases, making even the most complex inpatient dermatologic issues approachable and understandable for any clinician.

Litt's Drug Eruption & Reaction Manual

Author: Neil H. Shear

Publisher: CRC Press

Published: 2021-01-18

Total Pages: 508

ISBN-13: 1000364445

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Internationally relied upon by medical practitioners for its unparalleled focus on adverse effects and cutaneous reactions, Litt’s Drug Eruption & Reaction Manual is a succinct clinical reference and essential drug-safety tool for patient care. This 27th edition is a comprehensively revised and updated quick reference, and each entry includes: * Quantitative summaries of reports and incidence for reactions * Drug–drug interactions * Categories of adverse drug reactions, eruptions, and cutaneous reaction patterns * Essential reference information on prescription and over-the-counter drugs as well as herbals and supplements The book contains... * A to Z listing of the 1500 most consulted drug and herbal profiles, including generic name and trade names; pharmaceutical company; indications; half-life; and pregnancy category * Over 31,000 adverse reactions and drug-eruption listings * Includes supplements, vaccines, and botanicals * Clinical definitions of common and severe adverse reactions * List of drugs that cause severe adverse reactions * List of main classes of drugs as a quick clinical reference guide * 27 tables of members of a class of drugs (such as statins or monoclonal antibodies), enabling clinicians to see at a glance whether a reaction is common to all drugs included in that class, or to a majority of them, or is known in only a handful—information that is critical for an informed decision to change drugs within the same class * 2 extensive tables showing reported genetic associations with cutaneous adverse drug reactions and recommendations regarding genetic screening to prevent cutaneous adverse drug reactions * A concordance of synonyms and trade names for ease of cross-reference Markets: Dermatologists, Neurologists, Oncologists, Psychiatrists, Pharmacists, Family Physicians, and those caring for patients on multiple medications, such as Geriatricians and Hospital Generalist Physicians. Litt’s Drug Eruption & Reaction Manual is a succinct clinical reference derived from Litt’s Drug Eruption & Reaction Database, located at www.drugeruptiondata.com, which currently holds over 1750 drug profiles with almost 70,000 documented drug reactions, as evidenced by well over 145,000 references on PubMed. Quick and easy access via the Litt app provides real time access to the most up-to-date drug safety information to a busy practitioner on-the-go. Subscribers to the database benefit from: * Easy access via the Litt app, ideal for working across a number of work-places * Full drug profiles with a wealth of information including category, half-life, indications, drug-drug interactions, and known adverse reactions * Links to PubMed abstracts * Searching a class of drugs for a specific reaction * Searching by adverse reaction pattern * Searching by indication for a drug * Searching by drug name (generic name/brand name) as well as by pharmaceutical company or drug class * Searching herbal medicines and supplements * Diagnosing the cause of reactions in patients on multiple drugs by selecting the adverse reaction(s) experienced and the drug(s) the patient is taking * Comparing reaction profiles for up to four drugs in a customized chart that can be saved for future reference * Descriptions of reaction patterns * Photographs of adverse reactions * Access via a computer, tablet, or smartphone * Regular updates To learn more, and to subscribe to the database, visit www.drugeruptiondata.com.

Dermatologic Principles and Practice in Oncology

Author: Mario E. Lacouture

Publisher: John Wiley & Sons

Published: 2013-11-26

Total Pages: 764

ISBN-13: 1118590600

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The first book focusing specifically on frequent and frequently disabling side effects involving the skin, hair and nails in cancer patients According to the World Health Organization, there are approximately thirty million people living with a diagnosis of cancer – the majority of whom will receive surgery, systemic therapy, and/or radiation, and who will suffer from dermatologic adverse events. Dermatologists and oncologists are only beginning to grapple with these events, which pose serious quality-of-life issues with so many patients, and will become more prevalent as survival rates improve, thanks in part to new cancer treatments and drug regimens. Concentrating on a topic that has only been briefly touched upon by other texts, this book offers a focused perspective on the clinical presentation, underlying pathophysiologic mechanisms, and management of skin, hair, and nail conditions for oncologists, dermatologists, and allied practitioners. Dermatologic Principles and Practice in Oncology: Conditions of the Skin, Hair, and Nails in Cancer Patients: • Covers in detail the dermatologic adverse events of oncologic therapies, clinical presentations, and treatment recommendations • Enables dermatologists and other practitioners to significantly improve the care of patients with cancer • Addresses the dermatologic adverse events of cancer therapies used globally, of which a large number are found in developing countries • Emphasizes prophylactic measures – based on treatments used and type of cancer – to prevent the appearance of adverse events • Provides built-in discussions on patient education for practical counseling during therapies • Offers rapid-reference sections on topical dermatology drugs The first book to present dermatologic conditions in cancer patients and survivors in a uniform and in-depth manner, Dermatologic Principles and Practice in Oncology is ideal for oncologists, oncology nurses, and dermatologists who wish to take better care of those with adverse skin, hair, and nail conditions.

Dermatology Made Easy

Author: Amanda Oakley

Publisher: Scion Publishing Ltd

Published: 2017-05-06

Total Pages: 438

ISBN-13: 1911510118

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A concise overview of the common dermatological conditions most likely to present in general medicine From reviews: "... a perfect solution to the constant struggle that dermatology diagnosis presents to primary care physicians and other providers... This well-formatted book covers a vast array of topics ranging from common to rare skin disorders. The pictures are immensely helpful in the understanding of various skin rashes...." Fam Med 2019;51(5):451–452. “... easy to read and informative. One cannot emphasise enough the quality and comprehensive nature of the photographic content.... As someone who was interested in dermatology even as a medical student my only regret is that this book was not around when I was a student as it would have very adequately guided me into my beloved subspecialty.” Ulster Med J 2017;86(3):1–1. “The introduction outlines dermatological conditions by symptom, morphology and body site, providing an excellent index prior to delving into greater detail in the following chapters. The logical approach and level of detail make this text perfect for medical students, interns/residents, primary care physicians and other specialists who wish to quickly identify differential diagnoses or refresh their knowledge of dermatological conditions.” A Lecturer in Dermatology Dermatology Made Easy is based on the hugely popular DermNet New Zealand website and is designed to help GPs, medical students and dermatologists diagnose skin conditions with confidence. The book starts by providing a series of comprehensive tables, complete with over 500 thumbnail photos, to aid diagnosis according to symptoms, morphology, or body site. Once you have narrowed down the diagnosis, cross-references then guide you to more detailed descriptions, and another 700 photographs, covering: common infections inflammatory rashes non-inflammatory conditions skin lesions Every section provides consistent information on the disorder: who gets it and what causes it? what are the clinical features and does it cause any complications? how do you diagnose it? how do you treat it and how long does it take to resolve? The book concludes with a comprehensive section on further investigations and treatment options. Dermatology Made Easy combines the essential focus of the Made Easy book series with the authority and knowledge base of DermNet New Zealand’s unparalleled resources. Printed in full colour throughout.

Drug Eruptions

Author: Haur Yueh Lee

Publisher: Springer Nature

Published: 2022-10-27

Total Pages: 347

ISBN-13: 3031093887

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Cutaneous adverse drug reactions are common and range from the benign to those which are life-threatening. The clinical presentation of these dermatoses is varied and many may mimic common skin conditions. Consequently, diagnosis in drug-induced skin disease is challenging and the treatment considerations are complex. This book aims to bridge the divide between dermatology and allergy by providing a comprehensive review on the pathomechanisms and clinical features of cutaneous adverse drug reactions. Broken up into three distinct sections: General Considerations, Reaction Patterns, and Special Drug Categories, these chapters cover the common and rare adverse skin reactions and provide information on recent advances - particularly immunopathology and pharmacogenetics - as well as highlighting new adverse drug signals and novel therapies. Drug Eruptions is a must-have resource for dermatologists, allergists, internal physicians and general practitioners.

Fitzpatrick's Dermatology, 9e

Author: Sewon Kang

Publisher:

Published: 2019

Total Pages: 2272

ISBN-13: 9780071837811

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Treatment of Skin Diseases

Author: Zohra Zaidi

Publisher: Springer

Published: 2018-10-24

Total Pages: 551

ISBN-13: 3319895818

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This book summarises the key clinical features and their treatment across a range of skin diseases and describes the decision-making process when referring patients to specialists. It describes how treatment of the skin is often very different to other specialities, as both topical and systemic medications are used, and reviews the clinical signs, investigation and diagnostic approaches to skin diseases. Treatment of Skin Diseases: A Practical Guide principally aids primary care physicians, trainee dermatologists and dermatology nurse practitioners, but it is also a convenient management guide for allied health professionals, students and hospital-based physicians. A concise atlas of diagnostic photographs is included and incorporated with a simple set of common differentials to provide a useful reference for primary care readers and those training in dermatology. The book also contains information on the management of common skin problems, together providing a comprehensive introduction to the treatment of skin diseases. The treatment options for secondary and tertiary care are also included to provide a thorough picture of the spectrum of dermatologic therapeutics.