Craniopharyngiomas - Classification and Surgical Treatment

Craniopharyngiomas - Classification and Surgical Treatment PDF

Author: Songtao Qi

Publisher: Bentham Science Publishers

Published: 2017-12-05

Total Pages: 437

ISBN-13: 1681085321

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Craniopharyngiomas are a type of brain tumour in the suprasellar region with benign histological and cellular features. Clinical manifestations of craniopharyngiomas include decreased vision, hypopituitarism, hypothalamus dysfunction, fluid and electrolyte imbalance, glycometabolism, lipid metabolism and obesity. Craniopharyngiomas can show some characteristics of malignant tumours, such as invasion to the surrounding tissues, repetitious recurrence, and rapid growth. These characteristics cause considerable difficulty in patient treatment for neurosurgeons all over the world. This volume presents detailed information about craniopharyngioma anatomy, classification and treatment.

Craniopharyngiomas - Classification and Surgical Treatment

Craniopharyngiomas - Classification and Surgical Treatment PDF

Author: Songtao Qi

Publisher:

Published: 2017-12-05

Total Pages: 437

ISBN-13: 9781681085333

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Craniopharyngiomas are a type of brain tumour in the suprasellar region with benign histological and cellular features. Clinical manifestations of craniopharyngiomas include decreased vision, hypopituitarism, hypothalamus dysfunction, fluid and electrolyte imbalance, glycometabolism, lipid metabolism and obesity. Craniopharyngiomas can show some characteristics of malignant tumours, such as invasion to the surrounding tissues, repetitious recurrence, and rapid growth. These characteristics cause considerable difficulty in patient treatment for neurosurgeons all over the world. This volume presents detailed information about craniopharyngioma anatomy, classification and treatment. Key features: - Detailed references based on the clinical data of more than 400 craniopharyngioma cases, and cadaveric anatomical findings of the relationship between tumours and surrounding structures. - A new proposed topographic classification of craniopharyngiomas explained with corresponding surgical techniques for treatment. - Analytical presentation with references to medical literature. - Information about quality of life (QOL) and endocrinology evaluation relevant to craniopharyngioma treatment - 30 typical clinical cases with more than 500 clear anatomical pictures, radiological and intra-surgical images, and delicate schematic and ideographic diagrams. This reference is an essential information resource on craniopharyngiomas for neurosurgeons (adult and pediatric), neuro-endocrinologists, neuro-radiologists, ophthalmologists and medical residents.

Craniopharyngioma

Craniopharyngioma PDF

Author: Giovanni Broggi

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 164

ISBN-13: 8847022916

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Craniopharyngioma represents a major challenge for neurosurgeons, pediatricians, and endocrinologists. This so-called benign tumor is a real threat to quality of life and life itself. This book discusses the various therapeutic strategies and suggests multimodal treatment approaches, including microsurgery, stereotaxis, and alternative treatments. The rationale for choice of therapy is supported by biological, clinical, and neuroradiological data and therapeutic results of a large series of case studies from all over the world are reported. Finally, guidelines for further development and new topics for research and treatment are offered.

Atlas of Craniopharyngioma

Atlas of Craniopharyngioma PDF

Author: Songtao Qi

Publisher: Springer Nature

Published: 2019-10-17

Total Pages: 167

ISBN-13: 9811373221

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This book aims to facilitate readers to understand the origin, growth pattern and relationship between tumor and adherent structure of craniopharyngioma, so as to improve the cure rate and safety of surgery. It’s contributed by Neurosurgery Department of Nanfang Hospital, Southern Medical University, China, which focuses on the management of craniopharyngioma. This book covers histoembryology of craniopharyngioma, together with anatomical morphology and abundant clinical data, systematically showing an innovative classification method, i.e. QST classification. This classification method can better reflect the different origin and growth pattern of craniopharyngioma,the relationship between tumors and surrounding structure of the tumor growth pattern, and clinical significance in surgery. The 70 clinical cases with different classification and treatment history are discussed as an important reference for surgical treatment of craniopharyngioma. The anatomy, morphology and pathology of sellar region also have great reference value for researchers in the field of neural science. The underlying intention of this book is to help bring a change in the concept that “craniopharyngioma is an incurable benign tumor only due to its anatomical location”.

Diagnosis and Management of Craniopharyngiomas

Diagnosis and Management of Craniopharyngiomas PDF

Author: Andrea Lania

Publisher: Springer

Published: 2016-04-06

Total Pages: 153

ISBN-13: 331922297X

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This book provides up-to-date coverage of the most relevant topics in the diagnosis and management of craniopharyngiomas. After introductory discussion of natural history and clinical presentation, individual chapters are devoted to pathological and molecular aspects, use of diagnostic imaging techniques, the surgical approach to craniopharyngiomas, radiotherapy and radiosurgery, and associated endocrine disturbances. A particular feature of the book is the detailed attention devoted to the metabolic consequences of the disease and related treatments, including obesity and electrolyte disturbances, and to cognitive alterations. This book will be of value to oncologists, neurosurgeons, and endocrinologists by assisting in diagnostic workup, delivery of appropriate treatment, and management of the serious metabolic and endocrine consequences.

Adult Craniopharyngiomas

Adult Craniopharyngiomas PDF

Author: Emmanuel Jouanneau

Publisher: Springer Nature

Published: 2020-04-09

Total Pages: 231

ISBN-13: 3030411761

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This volume focuses on adult craniopharyngiomas, offering various perspectives. The first part of the book provides an up-to-date overview of the pathogenesis and management of adult craniopharyngiomas, helping readers understand the pathogenesis and molecular pathways. It highlights the importance of animal models for addressing molecular keys and for developing targeted therapies. The second part deals with clinical management, detailing the latest results in the era of endoscopic surgery, including the major contribution of the extended nasal endoscopic approaches for suprasellar and retrochiasmatic tumors. The book also discusses the key aspects of these tumors and how to manage them. The last part of the book addresses the future therapies and recurrences after surgery and radiotherapy. This volume is of interest to neurosurgeons, endocrinologists, paediatricians, radiologists and oncologists.

Oxford Textbook of Neurological Surgery

Oxford Textbook of Neurological Surgery PDF

Author: Ramez Kirollos

Publisher: Oxford University Press, USA

Published: 2019-09-05

Total Pages: 1177

ISBN-13: 0198746709

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Neurosurgery is a rapidly developing and technically demanding branch of surgery that requires a detailed knowledge of the basic neuro-sciences and a thorough clinical approach. The Oxford Textbook of Neurological Surgery is an up-to-date, objective and readable text that covers the full scope of neurosurgical practice. It is part of the Oxford Textbooks in Surgery series, edited by Professor Sir Peter Morris. The book is split into 20 overarching sections (Principles of Neurosurgery, Neuro-oncology of Intrinsic Tumours; Extra-axial Tumours and Skull Lesions; Cerebro-Pontine Angle Tumours; Sellar and Supra-Sellar Tumours; Posterior Fossa Tumours; Pineal tumours; Uncommon Tumours and Tumour Syndromes; Neurotrauma and Intensive Care; Vascular Neurosurgery; Principles of Spinal Surgery; Spinal Pathology; Spinal Trauma; Peripheral Nerve Surgery; Functional Neurosurgery; Epilepsy; Paediatric Neurosurgery; Neurosurgery for Cerebrospinal Fluid Disorders and Neurosurgical Infection). Each section takes a dual approach with, 'Generic Surgical Management' chapters that focus on specific clinical problems facing the neurosurgeon (e.g. sellar/supra-sellar tumour, Intradural Spina Tumours etc.) and 'Pathology-Specific' chapters (e.g. Glioma, Meningeal Tumours, Scoliosis and Spinal Deformity, Aneurysm etc.). Where appropriate, this division provides the reader with easily accessible information for both clinical problems which present in a regional fashion and specific pathologies. The generic chapters cover aspects such as operative approaches, neuroanatomy and nuances. Specifically each chapter in the book incorporates several strands. Firstly the fundamental neuroscience (anatomy, pathology, genetics etc.) that underlies the clinical practice. Secondly, a review of the requisite clinical investigations (e.g. angiography, electrodiagnostics, radiology). Thirdly, a thorough evidence based review of clinical practice. Following this a consideration of the key debates and controversies in the field with 'pro-' and 'con-' sections (e.g. minimally invasive spine surgery, microsurgical treatment of aneurysms) is provided. A summary of the key papers and clinical scales relevant to neurosurgery form the concluding part. The book is a 'one-stop' text for trainees and consultants in neurosurgery, residents, those preparing for sub-specialty exams and other professionals allied to surgery who need to gain an understanding of the field. It acts as both a point of reference to provide a focussed refresher for the experienced neurosurgeon as well as a trusted training resource.

Endocrine and Metabolic Late Effects in Cancer Survivors

Endocrine and Metabolic Late Effects in Cancer Survivors PDF

Author: Francesco Felicetti (Oncologist)

Publisher:

Published: 2021

Total Pages: 162

ISBN-13: 9783318067903

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This book analyzes in detail all aspects related to endocrine and metabolic late effects observed in patients treated for cancer, both in childhood and adulthood. The chapters focusing on the possible pathogenic mechanisms of late effects (i.e., premature aging and chronic inflammation) and on bone health in cancer survivors are particularly interesting and innovative. The volume also deals with hypothalamic-pituitary, thyroid and gonadal disorders, including infertility and how to prevent it. Finally, the relationship between metabolic alterations and cardiovascular diseases in cancer survivors is addressed. Thanks to advances in cancer treatment and supportive care, the five-year survival rate of cancer patients is constantly increasing. However, this undisputable success of medicine has a flip side: the late adverse effects of anticancer therapies. Pediatric oncologists were the first to cope with late complications of treatments, but today also adult oncologists and onco-hematologists recognize the relevance of this issue. Even though late effects observed in cancer survivors can affect any organ or system, endocrine and metabolic dysfunctions are the most frequently reported. Endocrine complications rarely influence life expectancy of cancer survivors, but they can significantly impact morbidity and quality of life. Among endocrine adverse effects, severe hypothalamic damage may be considered the most harmful in survivors, leading to morbid obesity, propensity to metabolic syndrome and cardiovascular disease. This book aims to disseminate the knowledge about endocrine and metabolic adverse effects of cancer therapies and about survivorship care. Since the number of cancer survivors is steadily growing in the general population, this publication is intended not only for endocrinologists but also for oncologists, onco-hematologists, internists, pediatric specialists in those areas and general practitioners, with the aim to better counsel and monitor cancer survivors.

Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma

Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma PDF

Author: Juan Pedro Martinez-Barbera

Publisher: Springer

Published: 2017-04-19

Total Pages: 220

ISBN-13: 3319518909

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This astute volume brings together the latest expert research on adamantinomatous craniopharyngiomas (ACPs). ACPs are histologically benign but clinically aggressive tumors exhibiting a high propensity for local invasion into the hypothalamus, optic and vascular structures. These tumors, as well as the current treatments, may result in pan-hypopituitarism, diabetes insipidus, morbid obesity followed by type II diabetes mellitus, blindness, as well as serious behavioral and psychosocial impairments. Exploring in detail advances in both the understanding of tumor biology as well as clinical advances in patient management are explored in detail, this book will also look towards potential new treatment approaches. Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma is the first book compiling all current research on ACPs. Mouse and human studies have unequivocally demonstrated that mutations in CTNNB1 encoding -catenin underlie the etiology of the majority, if not all ACP tumors. Genetic studies in mice have shown that ACPs are tumors of the pituitary gland and not of the hypothalamus as previously thought, and are derived from Rathke’s pouch precursors. In addition, a role for tissue-specific adult pituitary stem cells has been revealed as causative of ACP. Together, these studies have provided novel insights into the molecular and cellular etiology as well as the pathogenesis of human ACP. Finally, this volume covers new treatment approaches that have been shown to be effective both in reducing ACP burden as well as reducing the morbidity associated with therapy.

Practical Surgical Neuropathology: A Diagnostic Approach E-Book

Practical Surgical Neuropathology: A Diagnostic Approach E-Book PDF

Author: Arie Perry

Publisher: Elsevier Health Sciences

Published: 2017-10-16

Total Pages: 640

ISBN-13: 0323508669

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Part of the in-depth and practical Pattern Recognition series, Practical Surgical Neuropathology, 2nd Edition, by Drs. Arie Perry and Daniel J. Brat, helps you arrive at an accurate CNS diagnosis by using a pattern-based approach. Leading diagnosticians in neuropathology guide you from a histological (and/or clinical, radiologic, and molecular) pattern, through the appropriate work-up, around the pitfalls, and to the best diagnosis. Almost 2,000 high-quality illustrations capture key neuropathological patterns for a full range of common and rare conditions, and a "visual index" at the beginning of the book directs you to the exact location of in-depth diagnostic guidance. Instructive algorithms provide detailed guidance based on 8 major (scanning magnification) patterns and 20 minor (high magnification) patterns – helping you narrow the range of diagnostic possibilities. A user-friendly design color-codes patterns to specific entities, and key points are summarized in tables, charts, and graphs so you can quickly and easily find what you are looking for. Sweeping content updates keep you at the forefront of recent findings regarding gliomas, embryonal neoplasms, meningiomas, pituitary region and pineal tumors, epilepsy pathology, peripheral nerve sheath tumors, neurodegenerative disorders, tumor predisposition syndromes, and much more. Improved pattern call-outs are now linked directly within the chapter, reinforcing the patterns for more efficient and complete understanding.