Coronary Stenosis Morphology
Author: Lloyd W Klein
Publisher:
Published: 1997-04-01
Total Pages: 416
ISBN-13: 9781461562887
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Coronary Stenosis Morphology: Analysis and Implication
Author: Lloyd W. Klein
Publisher: Springer
Published: 2012-12-06
Total Pages: 313
ISBN-13: 1461562872
DOWNLOAD EBOOK →In this book, the importance and value of accurately assessing coronary stenosis morphology is reviewed, including recent thoughts regarding the pathogenetic mechanisms ascribed to angiographically assessed morphology, several new and potentially more accurate means of determining plaque composition and its relationship to stenosis morphology, and the latest hypotheses regarding interventional device selection. Each chapter has been written by acknowledged experts in the area, who have contributed significantly to that body of knowledge and are considered opinion leaders nationally and internationally. Each chapter contains the basic `how-to' of that technique, the manner in which it is best utilized or considered, and the limitations that must be taken into account in its application. In some chapters, the authors address guidelines regarding image acquisition and analysis to minimize the variations resulting from the potential error sources. It is hoped that this work will lead to technological developments, improved performance, and more rational clinical utilization.
Chronic Total Occlusions
Author: Ron Waksman
Publisher: John Wiley & Sons
Published: 2011-08-31
Total Pages: 373
ISBN-13: 1444357263
DOWNLOAD EBOOK →Chronic total occlusions (CTO) are common, and found in approximately one third of patients with significant coronary artery disease who undergo angiography. Over the past 20 years, CTO lesions have represented the most difficult anatomy for treatment — with lower success rates and higher complication rates. Chronic Total Occlusions provides interventionalists insight into the world of CTOs with introductory chapters that describe the pathology and indications of CTOs along with a review of clinical trials. Imaging modalities including CT angiography, magnetic navigation wire, and IVUS guided recanalization of CTO are also introduced, together with information on new wires technology and devices for CTOs. With numerous illustrations of these devices, technologies, and strategies to improve the CTO success rate, this clinical guide, headed up by Ron Waksman, will prove to be the ideal companion for interventional cardiologists and cardiac surgeons who are required to perform angioplasty and coronary stenting.
Managing Discovery in the Life Sciences
Author: Philip A. Rea
Publisher: Cambridge University Press
Published: 2018-02
Total Pages: 557
ISBN-13: 1107130905
DOWNLOAD EBOOK →Addresses in roughly equal measure the science and management behind several recent marketable biomedical innovations.
Textbook of Coronary Thrombosis and Thrombolysis
Author: R. C. Becker
Publisher: Springer Science & Business Media
Published: 2008-01-21
Total Pages: 660
ISBN-13: 0585337543
DOWNLOAD EBOOK →Teleologically, the hemostatic mechanism is among The of Coronary Thrombosis and the most fundamental yet complex physiologic pro- in essence, represents a heartfelt gift of cesses in humans. Early scientists and physicians were knowledge from a dedicated group of scientists and fascinated by the blood's ability to remain in a liquid clinicians, who collectively have set out on a mission state only to clot in response to vascular injury. The to minimize the societal impact of"hemostasis in the cellular and noncellular components of normal wrong place. " The book is divided into four distinct hemostasis took centuries to discover, and the intrica- sections: Part 1, Scientific Principles, lays down the cies of their delicate interactions are still being unrav- supporting foundation; Part 2, Clinical Application eled today. As is so often the case, an in-depth of Scientific Principles, places the knowledge base in appreciation of physiologic hemostasis, representing a a working perspective, directly applying science to basic life-sustaining sequence of events, paved the patient care; Part 3, New Dimensions, provides a way for understanding abnormal hemostasis or glimpse of tomorrow. Steering the field clear of se- pathologic thrombosis. Aristotle, Malpighi, and proclaimed victory and the dangers of complacency as Osier, representing but a few of the founding fathers we move into the 21st century, Part 4, Evolution of in the field, would undoubtedly be honored to see Thrombocardiology, focuses on laboratory standards, their observations form the template for lifesaving clinical trials, and drugs in development.
Cardiovascular Genetics for Clinicians
Author: P.A.F.M. Doevendans
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 256
ISBN-13: 9401010196
DOWNLOAD EBOOK →All physicians practicing medicine encounter patients suffering from cardiovascular disease. This book has been outlined in such a way that vascular surgeons, general internists, neurologists and cardiologists should be able to use it. The book covers the complete scope of cardiac diseases in addition to chapters on hypertension and atherosclerosis. In many patients there is a family history of cerebrovascular accidents, myocardial infarction or peripheral arterial disease. Also in patients reporting collaps, palpitations and arrhythmias the family is crucial and can provide clues to a genetic cause of the disease. This book is published to guide physicians in the process of determining whether a genetic component is likely to be present. Furthermore, information is provided what the possibilities and limitations of DNA diagnostic techniques are. Finally, the importance of newly identified categories of potential patients, i. e. gene carriers without symptoms or any inducible sign of disease, is highlighted. For some patients a genetic diagnosis is essential to determine appropriate therapy and for counseling? In some other diseases DNA diagnostic tools are available but the relevant for the patients may be less clear. In other families the search for a disease causing gene is ongoing and the possibilities to find genes and to unravel the pathophysiology of the disease is limited by the lack of patients. To give insight into the current state of genetic diagnostics, the authors have classified the cardiovascular diseases.
Cardiovascular Specific Gene Expression
Author: P.A.F.M. Doevendans
Publisher: Springer Science & Business Media
Published: 2013-04-17
Total Pages: 328
ISBN-13: 9401593213
DOWNLOAD EBOOK →Improving our insights into the genetic predisposition to cardiovascular disease is one of the most important challenges in our field in the next millennium, not only to unravel the cause of disease but also to improve the selection of patients for particular treatments. Nowadays, for example, subjects with a cholesterol above a particular plasma level are exposed to a cholesterol lowering regime based upon the beneficial outcome of epidemiological studies which include subjects not prone to the disease, despite a plasma cholesterol above the accepted level. Identification of the patients who are genetically predisposed to the consequences of this disorder will reduce the number of subjects unnecessarily treated and, hence, the costs of health care. Because in most cardiovascular diseases the genetic component is a consequence of more than one gene defect, only limited progress has as yet been made in identifying subjects genetically at risk. For example, in hypertension only in less than 10% of the patients the genetic defect has been identified. It has been known for quite some time that in heart and blood vessels fetal genes are as high blood pressure and upregulated or induced when they are exposed to such disorders ischemia. Little is known about the function of these genes in the cardiac and vascular adaptation to these disorders; only guesses can be made.
Nondestructive Characterization and Imaging of Wood
Author: Voichita Bucur
Publisher: Springer Science & Business Media
Published: 2003-05-12
Total Pages: 378
ISBN-13: 9783540438403
DOWNLOAD EBOOK →This book on the Nondestructive Characterization and Imaging of Wood by Professor Voichita Bucur is truly the most outstanding reference on the subject ever written. Since the origins of mankind, wood has played a key role in the history of humans and other living creatures, ranging from provision of life from trees giving air, heat, light, and food to nourish their bodies to structures to protect them from the elements. Wood has also played a key role in one of the world's primary religions. Nondestructive diagnostics methods have long found application in medi cal practice for examination of the human body in order to detect life threatening abnormalities and permit diagnosis to extend life. Nondestructive testing has been used for many years to insure the safety of machinery, air craft, railroads, tunnels, buildings and many other structures. Therefore, it is timely for a treatise, like the present one, to be written describing how wood can be characterized without employing destructive test methods. Since wood is so valuable to mankind, it is important to know the latest methods to nondestructively characterize wood for all practical applications.
Myocardial Damage
Author: Juan Carlos Kaski
Publisher: Springer Science & Business Media
Published: 2013-03-09
Total Pages: 220
ISBN-13: 940172380X
DOWNLOAD EBOOK →The spectrum of unstable coronary syndromes has been the object of steadily increasing research particularly in respect of novel diagnostic and treatment modalities. Although the WHO criteria for the diagnosis of acute myocardial infarction have been known for decades, there is still much debate as to the proper use of these, especially the handling of biochemical markers. Traditional enzymes have limitations in diagnostic power and new markers have unclarified applicability with regard to standardisation of assays and decision limits. Furthermore, the growing understanding of the conception of minimal myocardial damage in the borderzone between unstable angina pectoris and myocardial infarction necessitates refinement in the definitions of the various entities within the kaleidoscope of acute myocardial ischaemia. There has been a strong impetus within the European Society of Cardiology to present this subject to a broad audience of cardiologists, and as a consequence the theme of biochemical markers has become an important constituent of the Education and Training Programmes of the Society. This book has fundamental implications for the overall comprehension of this complex area. This book on myocardial damage, compiled by international experts, will truly appeal to the basic scientist as well as the clinician searching for updated knowledge of the pathophysiology and risk stratification of unstable coronary syndromes.
Delayed Preconditioning and Adaptive Cardioprotection
Author: G.F. Baxter
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 240
ISBN-13: 9401153124
DOWNLOAD EBOOK →Interest in the ability of myocardium to adapt to ischaemic stress has continued to grow since the discovery of ischaemic preconditioning in 1986. In 1993, two reports heralded the recognition of a delayed preconditioning response in the heart, now commonly known as the `second window' of protection. Since then, a number of studies have described the ability of delayed preconditioning and related adaptive phenomena to protect against a variety of pathologies in the ischaemic and reperfused myocardium. Our understanding of the cellular mechanisms of sub-acute adaptive cardioprotection has advanced considerably during this period. This compilation of state-of-the-art reviews by those who have made significant contributions to this field provides detailed and critical analysis of this research, from molecular basis to potential clinical relevance. The book aims to provide an authoritative, comprehensive and thoroughly up-to-date overview for scientists and clinicians engaged in, or observing, this rapidly-developing area of heart research. It will also be of interest to those engaged in research on other tissues where ischaemia-reperfusion pathology is of major concern.
