Converging Pharmacy Science and Engineering in Computational Drug Discovery

Converging Pharmacy Science and Engineering in Computational Drug Discovery PDF

Author: Tripathi, Rati Kailash Prasad

Publisher: IGI Global

Published: 2024-04-22

Total Pages: 337

ISBN-13:

DOWNLOAD EBOOK →

The world of pharmaceutical research is moving at lightning speed, and the age-old approach to drug discovery faces many challenges. It's a fascinating time to be on the cutting edge of medical innovation, but it's certainly not without its obstacles. The process of developing new drugs is often time-consuming, expensive, and fraught with uncertainty. Researchers are constantly seeking ways to streamline this process, reduce costs, and increase the success rate of bringing new drugs to market. One promising solution lies in the convergence of pharmacy science and engineering, particularly in computational drug discovery. Converging Pharmacy Science and Engineering in Computational Drug Discovery presents a comprehensive solution to these challenges by exploring the transformative synergy between pharmacy science and engineering. This book demonstrates how researchers can expedite the identification and development of novel therapeutic compounds by harnessing the power of computational approaches, such as sophisticated algorithms and modeling techniques. Through interdisciplinary collaboration, pharmacy scientists and engineers can revolutionize drug discovery, paving the way for more efficient and effective treatments. This book is an invaluable resource for pharmaceutical scientists, researchers, and engineers seeking to enhance their understanding of computational drug discovery. This book inspires future innovations by showcasing cutting-edge methodologies and innovative research at the intersection of pharmacy science and engineering. It contributes to the ongoing evolution of pharmaceutical research. It offers practical insights and solutions that will shape the future of drug discovery, making it essential reading for anyone involved in the pharmaceutical industry.

Blockchain and IoT Approaches for Secure Electronic Health Records (EHR)

Blockchain and IoT Approaches for Secure Electronic Health Records (EHR) PDF

Author: Saini, Kavita

Publisher: IGI Global

Published: 2024-05-28

Total Pages: 286

ISBN-13:

DOWNLOAD EBOOK →

In the realm of healthcare, the persistent challenges of data breaches, centralized systems, and fraudulent claims have posed significant hurdles in ensuring the integrity and security of patient information. The traditional approaches to managing Electronic Health Records (EHR) often fall short, leaving room for exploitation and compromising the confidentiality of sensitive medical data. Enter the transformative solution presented in Blockchain and IoT Approaches for Secure Electronic Health Records (EHR). This groundbreaking book navigates the intricate landscape of healthcare technology, addressing the vulnerabilities in the current systems. By leveraging the power of Blockchain technology, it pioneers a secure peer-to-peer communication system that not only ensures the tamper-proof nature of health records but also revolutionizes the entire healthcare industry. The book is a comprehensive exploration of Blockchain's relevance in healthcare, covering the architecture, scope, and applications that promise to redefine how patient data is managed and protected.

Lightweight Digital Trust Architectures in the Internet of Medical Things (IoMT)

Lightweight Digital Trust Architectures in the Internet of Medical Things (IoMT) PDF

Author: Hassan, Ahdi

Publisher: IGI Global

Published: 2024-05-17

Total Pages: 471

ISBN-13:

DOWNLOAD EBOOK →

In the field of healthcare technology, the Internet of Medical Things (IoMT) stands at the forefront of progress, revolutionizing patient care through advanced monitoring and treatment modalities. However, this digital transformation brings forth a new challenge— the vulnerability of sensitive medical data to cyber threats. Lightweight Digital Trust Architectures in the Internet of Medical Things (IoMT) examines ways to fortify IoMT against potential breaches through the exploration of these trust architectures. Delving deep into data privacy technologies, the book examines the implications of regulatory frameworks such as GDPR, HIPAA, and cybersecurity law. It assesses traditional security methods and considers innovative approaches, offering insights into certificate generation, digital identification, and the optimization of network protocols for secure data transmission.Lightweight Digital Trust Architectures in the Internet of Medical Things (IoMT) illuminates the path forward for IoMT security. Its objectives are multi-faceted: from unraveling the intricacies of the health chain to dissecting the role of lightweight cryptographic key agreement mechanisms in safeguarding medical data. The book grapples with the challenges and advantages of implementing compact cryptographic techniques in healthcare, particularly within the decentralized framework of IoMT. By exploring the potential of Federated Learning (FL) in bolstering privacy and improving healthcare outcomes, the book aims to equip researchers, healthcare professionals, and IT experts with valuable knowledge. Through real-world case studies, it endeavors to pave the way for a future where security and efficiency seamlessly integrate in IoMT.

Chemical Engineering in the Pharmaceutical Industry

Chemical Engineering in the Pharmaceutical Industry PDF

Author: Mary T. am Ende

Publisher: John Wiley & Sons

Published: 2019-04-01

Total Pages: 688

ISBN-13: 1119285518

DOWNLOAD EBOOK →

A guide to the important chemical engineering concepts for the development of new drugs, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry offers a guide to the experimental and computational methods related to drug product design and development. The second edition has been greatly expanded and covers a range of topics related to formulation design and process development of drug products. The authors review basic analytics for quantitation of drug product quality attributes, such as potency, purity, content uniformity, and dissolution, that are addressed with consideration of the applied statistics, process analytical technology, and process control. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The contributors explore technology transfer and scale-up of batch processes that are exemplified experimentally and computationally. Written for engineers working in the field, the book examines in-silico process modeling tools that streamline experimental screening approaches. In addition, the authors discuss the emerging field of continuous drug product manufacturing. This revised second edition: Contains 21 new or revised chapters, including chapters on quality by design, computational approaches for drug product modeling, process design with PAT and process control, engineering challenges and solutions Covers chemistry and engineering activities related to dosage form design, and process development, and scale-up Offers analytical methods and applied statistics that highlight drug product quality attributes as design features Presents updated and new example calculations and associated solutions Includes contributions from leading experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduation students, and professionals in the field of pharmaceutical sciences and manufacturing, Chemical Engineering in the Pharmaceutical Industry, Second Edition contains information designed to be of use from the engineer's perspective and spans information from solid to semi-solid to lyophilized drug products.

Computational Drug Design

Computational Drug Design PDF

Author: D. C. Young

Publisher: John Wiley & Sons

Published: 2009-01-28

Total Pages: 344

ISBN-13: 9780470451847

DOWNLOAD EBOOK →

Helps you choose the right computational tools and techniques to meet your drug design goals Computational Drug Design covers all of the major computational drug design techniques in use today, focusing on the process that pharmaceutical chemists employ to design a new drug molecule. The discussions of which computational tools to use and when and how to use them are all based on typical pharmaceutical industry drug design processes. Following an introduction, the book is divided into three parts: Part One, The Drug Design Process, sets forth a variety of design processes suitable for a number of different drug development scenarios and drug targets. The author demonstrates how computational techniques are typically used during the design process, helping readers choose the best computational tools to meet their goals. Part Two, Computational Tools and Techniques, offers a series of chapters, each one dedicated to a single computational technique. Readers discover the strengths and weaknesses of each technique. Moreover, the book tabulates comparative accuracy studies, giving readers an unbiased comparison of all the available techniques. Part Three, Related Topics, addresses new, emerging, and complementary technologies, including bioinformatics, simulations at the cellular and organ level, synthesis route prediction, proteomics, and prodrug approaches. The book's accompanying CD-ROM, a special feature, offers graphics of the molecular structures and dynamic reactions discussed in the book as well as demos from computational drug design software companies. Computational Drug Design is ideal for both students and professionals in drug design, helping them choose and take full advantage of the best computational tools available. Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.

Software Innovations in Clinical Drug Development and Safety

Software Innovations in Clinical Drug Development and Safety PDF

Author: Chakraborty, Partha

Publisher: IGI Global

Published: 2015-10-02

Total Pages: 320

ISBN-13: 1466687274

DOWNLOAD EBOOK →

In light of the rising cost of healthcare and the overall challenges associated with delivering quality care to patients across regions, scientists and pharmacists are exploring new initiatives in drug discovery and design. One such initiative is the adoption of information technology and software applications to improve healthcare and pharmaceutical processes. Software Innovations in Clinical Drug Development and Safety is a comprehensive resource analyzing the integration of software engineering for the purpose of drug discovery, clinical trials, genomics, and drug safety testing. Taking a multi-faceted approach to the application of computational methods to pharmaceutical science, this publication is ideal for healthcare professionals, pharmacists, computer scientists, researchers, and students seeking the latest information on the architecture and design of software in clinical settings, the impact of clinical technologies on business models, and the safety and privacy of patients and patient data. This timely resource features a well-rounded discussion on topics pertaining to the integration of computational methods in pharmaceutical science and practice including, the impact of software integration on business models, patient safety concerns, software architecture and design, and data security.

Computational Drug Discovery and Design

Computational Drug Discovery and Design PDF

Author: Mohini Gore

Publisher: Humana

Published: 2023-10-19

Total Pages: 0

ISBN-13: 9781071634400

DOWNLOAD EBOOK →

This second edition provides new and updated methods and techniques for identification of drug target, binding sites prediction, high- throughput virtual screening, lead discovery and optimization, conformational sampling, prediction of pharmacokinetic properties using computer-based methodologies. Chapters also focus on the application of the latest artificial intelligence technologies for computer aided drug discovery. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary methods, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Computational Drug Discovery and Design, Second Edition aims to effectively utilize computational methodologies in discovery and design of novel drugs.

The Science and Business of Drug Discovery

The Science and Business of Drug Discovery PDF

Author: Edward D. Zanders

Publisher: Springer Nature

Published: 2020-11-09

Total Pages: 401

ISBN-13: 3030578143

DOWNLOAD EBOOK →

The Science and Business of Drug Discovery is written for those who want to learn about the biopharmaceutical industry and its products whatever their level of technical knowledge. Its aim is to demystify the jargon used in drug development, but in a way that avoids over simplification and the resulting loss of key information. Each of the twenty chapters is illustrated with figures and tables which clarify some of the more technical points being made. Also included is a drug discovery case history which draws the relevant material together into a single chapter. In recognizing that it is difficult to navigate through the many external resources dealing with drug development, the book has been written to guide the reader towards the most appropriate information sources, including those listed in the two appendices. The following topics are covered: Different types of drugs: from small molecules to stem cells Background to chemistry of small and large molecules Historical background to drug discovery, pharmacology and biotechnology The drug discovery pipeline: from target discovery to marketed medicine Commercial aspects of drug discovery Challenges to the biopharmaceutical industry and its responses Material of specific interest to technology transfer executives, recruiters and pharmaceutical translators

Drug Discovery and Development, Third Edition

Drug Discovery and Development, Third Edition PDF

Author: James J. O'Donnell

Publisher:

Published: 2019

Total Pages: 668

ISBN-13: 9781315113470

DOWNLOAD EBOOK →

"The Process of New Drug Discovery and Development, Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It explores many scientific advances in new drug discovery and development for areas such as screening technologies, biotechnology approaches, and evaluation of efficacy and safety of drug candidates through pre-clinical testing. This book also greatly expands the focus on the clinical pharmacology, regulatory, and business aspects of bringing new drugs to the market and offers coverage of essential topics for companies involved in drug development. Historical perspectives and predicted trends are also provided"--