-PDF Download- Controversial Issues In The Management Of Head And Neck Cancer A Swiss Multidisciplinary And Multi Institutional Patterns Of Care Study EBOOK

Controversial Issues in the Management of Head and Neck Cancer: A Swiss Multidisciplinary and Multi-Institutional Patterns of Care Study

Author: Olgun Elicin

Publisher: Frontiers Media SA

Published: 2020-02-26

Total Pages: 37

ISBN-13: 2889635449

The heterogeneity in the practice of diagnosis and treatment of head and neck squamous cell carcinoma (HNSCC) is known and expected to be inversely correlated with the level of evidence on a given topic. Literature on various aspects of management of HNSCC were previously published, but were usually restricted within narrow foci. Due to the lack of a similar comprehensive work published so far, the Head and Neck Cancer Working Group of Swiss Group for Clinical Cancer Research (SAKK) decided to perform a survey covering the whole spectrum of controversial topics concerning the diagnosis and the treatment of HNSCC among its member institutions. This survey was designed to discuss current diagnostic and treatment strategies for HNSCC of all localizations, and to find out probable differences and level of consensus between the participating academic institutions by means of a questionnaire-based pattern of care study. The items in the survey was generated with a scored voting system by inclusion of all involved centers, and divided into four sections, each of them not exceeding twenty questions: head and neck surgery, radiation oncology, medical oncology and biomarkers. Surely, the topics and questions were intentionally chosen from controversial areas. Nonetheless, the lack of major consensus in most queried areas provide an insight to head and neck oncologist in terms of the scope of heterogeneity in their practice. Although none of the participated centers being plainly wrong, it is still disturbing to see, that a patient may be treated with quite discrepant diagnostic and treatment concepts even in a relatively small country adhering to up to date evidence based medicine. We believe that this work will serve the head and neck oncologists to be aware of their discrepancies and to stimulate discussion toward standardization of practice and prioritize topics of future clinical research.

Surgical Management of Head and Neck Pathologies

Author: Ho-Hyun (Brian) Sun

Publisher: BoD – Books on Demand

Published: 2021-10-13

Total Pages: 192

ISBN-13: 1838819835

DOWNLOAD EBOOK →

The book is an introduction to concepts in head and neck surgical pathology that are both novel and proven. Chapters discuss the various anatomic, reconstructive, and esthetic considerations that are often unique to surgeries of the head, face, and neck. International cooperation was made to ensure that a wide range of perspectives is presented in this volume.

Metastases in Head and Neck Cancer

Author: Jochen A. Werner

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 262

ISBN-13: 3642187226

DOWNLOAD EBOOK →

-Richly illustrated; 109 illustrations, 57 in color -Cover a wide range of diagnostic and theraputic techniques, i.e. MRI, PET, surgical treatment, radiation therapy

Tumor Microenvironment

Author: Alexander Birbrair

Publisher: Springer

Published: 2021-06-27

Total Pages: 208

ISBN-13: 9783030445201

DOWNLOAD EBOOK →

Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research in the field. A variety of topics are covered, including metabolism in the tumor microenvironment, stellate cells and endothelial progenitors in the tumor microenvironment, as well as the effects of HIV, viral hepatitis, and inflammation in the tumor microenvironment, and more. Taken alongside its companion volumes, Tumor Microenvironment: State of the Science updates us on what we know about various aspects of the tumor microenvironment, as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Betel-quid and Areca-nut Chewing and Some Areca-nut-derived Nitrosamines

Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Publisher: IARC

Published: 2004

Total Pages: 354

ISBN-13: 9789283212850

DOWNLOAD EBOOK →

A working group of sixteen experts from seven countries re-evaluated the evidence of the carcinogenicity of betel-quid and areca-nut chewing and some areca-nut related nitrosamines. Betel-quid and areca-nut chewing are widely practised in many parts of Asia and in Asian-migrant communities elsewhere in the world. There are hundreds of millions of users worldwide. They evaluated betel quid with tobacco as carcinogenic to humans (Group 1) on the basis of sufficient evidence of an increased risk of cancer of the oral cavity, pharynx and oesophagus. The working group reviewed epidemiological studies of human cancer, mainly studies from India, Pakistan and Taiwan (China). Studies on betel quid with tobacco and areca nut with tobacco in experimental animals now also provide sufficient evidence of carcinogenicity. The working group also evaluated betel quid without tobacco as carcinogenic to humans (Group 1), on the basis of sufficient evidence of an increased risk of oral cancer. Studies on betel quid without tobacco and areca nut without tobacco in experimental animals now also provide sufficient evidence of carcinogenicity. Areca nut, a common ingredient of betel quid and many different chewing preparations, including those available commercially, has been observed to cause oral submucous fibrosis

Pain Management and the Opioid Epidemic

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2017-09-28

Total Pages: 483

ISBN-13: 0309459575

DOWNLOAD EBOOK →

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Carcinoma of the Larynx and Hypopharynx

Author: Sudhir Bahadur

Publisher: Springer

Published: 2019-02-20

Total Pages: 226

ISBN-13: 9811331103

DOWNLOAD EBOOK →

Carcinomas of the larynx and hypopharynx present unique challenges when it comes to their assessment and management. Management involves the essential dilemma of optimizing cure rates while also ensuring that potential disability due to compromised airway, voice and swallowing is minimized. Treatment decisions involve careful disease assessment, judicious multispecialty decision-making, and subsequent meticulous implementation of the selected treatment modalities. The critical nature of each of these steps has led to dramatic advances in assessment techniques (radiology, endoscopy and photography, stroboscopy, narrow band imaging, contact endoscopy) and also in treatment methods (radiation therapy, combined concurrent chemo-radiation, combined sequential chemo-radiation, trans-oral CO2 laser and robotic surgery, partial laryngectomy, total laryngectomy, extended total laryngectomy). As such, treatment decisions have become increasingly complex with the twin objectives of maximizing cure as well as function preservation and are based on tumor stage, tumor location, systemic co-morbidities, nutritional status, patient priorities, and social and economic factors. This multidisciplinary book has been written by a team of editors with considerable experience and expertise in these critical areas and a deep understanding of teamwork and the strengths and limitations of individual technologies and treatments. It presents a homogeneous and unbiased view that is applicable to all specialties involved in the care of larynx and hypopharynx cancers.

Cutaneous Adnexal Neoplasms

Author: Luis Requena

Publisher: Springer

Published: 2017-12-28

Total Pages: 1052

ISBN-13: 3319457047

DOWNLOAD EBOOK →

This superbly illustrated book is the most comprehensive available guide to adnexal neoplasms of the skin. More than 70 entities are described in individual chapters that follow a uniform structure: historical review, clinical features, histopathology, histogenesis, immunohistochemistry, molecular anomalies, and treatment. Readers will find state of the art knowledge on all aspects, including the cytogenetic and chromosomal abnormalities associated with each neoplasm. Without exception, the illustrations are high-quality, full-color, original digital pictures. The histopathology images are taken from perfectly cut and stained sections and the immunohistochemistry illustrations are of an unrivalled quality among textbooks of dermatology and dermatopathology. A complete list of references from original description to the present day is also supplied for each neoplasm. Cutaneous adnexal neoplasms are a large and heterogeneous group of benign and malignant lesions. This book will assist the reader in early and correct recognition, which is essential for appropriate choice of treatment and prognostic assessment.

Head and Neck Cancer

Author: N. J. Roland

Publisher:

Published: 2011

Total Pages: 354

ISBN-13: 9780957013803

DOWNLOAD EBOOK →

Anterior Skull Base Tumors

Author: P. Nicolai

Publisher: Karger Medical and Scientific Publishers

Published: 2020-07-30

Total Pages: 266

ISBN-13: 3318066702

DOWNLOAD EBOOK →

In recent years, interest in the management of anterior skull base tumors has been fostered by the introduction and subsequent rapid expansion of indications of transnasal endoscopic techniques. In parallel, extraordinary progress has been made in all the other disciplines which are involved in the complex process of managing anterior skull base tumors, leading to substantial improvements in diagnosis and treatment. The anterior skull base can be involved in a large variety of tumors of a varying nature and histology, which in the majority of cases originate from adjacent anatomic sites. In fact, primary lesions of the anterior skull base mainly include osteoma and other tumors originating from bone and cartilage. Tumors involving the anterior skull base have their origin prevalently in the sinonasal tract, but lesions developing on the intracranial site, such as meningiomas, may also extend caudally to encroach upon this area. All these lesions are rare, which means that the pertinent literature does not include prospective studies or treatment guidelines based on a high level of evidence. In view of the extreme histological variability of lesions involving the anterior skull base, much emphasis has been placed on addressing the different nuances of treatment in relation to histology, especially for malignant tumors. The chapters focusing on surgery provide divergent views on selection criteria for a specific surgical technique, which is the aim of this publication.