Comprehensive Toxicology, Volume 9

Comprehensive Toxicology, Volume 9 PDF

Author: R.S. McCuskey

Publisher: Pergamon

Published: 1999-08-18

Total Pages: 750

ISBN-13: 9780080429748

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This volume, which is separated into two parts, presents important new information concerning mechanisms of effect and consequences of exposure of the liver and gastrointestinal tract to a wide variety of toxicants. Both sections on the liver and GI tract provide the reader with concise introductory descriptions of relevant cellular and organ anatomy, physiology, and mechanisms of toxic injury. Specific consideration is given to methods of toxin exposure and to processes that provide defence against injury. The discussions provide a broad focus but also contain details about molecular, cellular, and biochemical mechanisms. The section on the liver (34 chapters) provides a comprehensive review of the toxic effects of a wide variety of specific compounds including volatile hydrocarbons, anesthetic agents, drugs of therapeutic value as well as of abuse, heavy metals, natural compounds etc. The section on the gastrointestinal tract (15 chapters), presenting toxicology of the esophagus, stomach, small intestine, and colon, represents the first major reference work available that provides both a broad overview of the effect of toxicants on the mucosal, motility, and immune functions of the GI tract as well as specific information about specific toxicants. The final chapter presents an overview of clinical toxicology in animals with specific focus on the liver and gastrointestinal systems. This volume is of specific interest and use to those concerned with environmental and industrial toxicology, as well as with mechanisms of toxicant injury and clinical medicine.

Comprehensive Toxicology

Comprehensive Toxicology PDF

Author:

Publisher: Elsevier

Published: 2017-12-01

Total Pages: 8639

ISBN-13: 0081006128

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Comprehensive Toxicology, Third Edition, Fifteen Volume Set discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology. Organized to cover both the fundamental principles of toxicology and unique aspects of major organ systems Thoroughly revised to include the latest advances in the toxicological effects of chemicals on the immune system Features additional coverage throughout and a new volume on toxicology of the hematopoietic system Presents in-depth, comprehensive coverage from an international author base of domain experts

Comprehensive Toxicology, Volume 9

Comprehensive Toxicology, Volume 9 PDF

Author: R.S. McCuskey

Publisher: Pergamon

Published: 1999-08-04

Total Pages: 0

ISBN-13: 9780080429748

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This volume, which is separated into two parts, presents important new information concerning mechanisms of effect and consequences of exposure of the liver and gastrointestinal tract to a wide variety of toxicants. Both sections on the liver and GI tract provide the reader with concise introductory descriptions of relevant cellular and organ anatomy, physiology, and mechanisms of toxic injury. Specific consideration is given to methods of toxin exposure and to processes that provide defence against injury. The discussions provide a broad focus but also contain details about molecular, cellular, and biochemical mechanisms. The section on the liver (34 chapters) provides a comprehensive review of the toxic effects of a wide variety of specific compounds including volatile hydrocarbons, anesthetic agents, drugs of therapeutic value as well as of abuse, heavy metals, natural compounds etc. The section on the gastrointestinal tract (15 chapters), presenting toxicology of the esophagus, stomach, small intestine, and colon, represents the first major reference work available that provides both a broad overview of the effect of toxicants on the mucosal, motility, and immune functions of the GI tract as well as specific information about specific toxicants. The final chapter presents an overview of clinical toxicology in animals with specific focus on the liver and gastrointestinal systems. This volume is of specific interest and use to those concerned with environmental and industrial toxicology, as well as with mechanisms of toxicant injury and clinical medicine.

Toxicology of the Gastrointestinal Tract, Second Edition

Toxicology of the Gastrointestinal Tract, Second Edition PDF

Author: Shayne Cox Gad

Publisher: CRC Press

Published: 2018-10-26

Total Pages: 477

ISBN-13: 042978144X

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Nanoparticles as both potential unique risks and as a valuable approach to increased and higher specificity in delivery of therapeutics A primer on the largest, most diverse, and important microbiome in any mammal "Tricks of the trade" on modifying the oral administration of drugs