Collagen, from Tissue Culture to Biomaterials, Tissue Engineering, and Beyond

Collagen, from Tissue Culture to Biomaterials, Tissue Engineering, and Beyond PDF

Author: Elena García-Gareta

Publisher: Cambridge Scholars Publishing

Published: 2019-01-21

Total Pages: 152

ISBN-13: 1527526461

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As collagen is the main structural component of body tissues, there has been much effort expended, both in the past and today, to use it in cell culture applications. Indeed, its importance is further stressed by the wide use of collagen biomaterials in tissue repair and regeneration, including the treatment of burns, chronic wounds or bone repair. This book represents a journey through recent scientific history, and describes the massive implications of the research carried out by Bornstein, Ehrmann and Gey on collagen preparations in the 1950s for cell culture and more recently, tissue engineering and personalised medicine.

Tissue Engineering

Tissue Engineering PDF

Author: Yoshito Ikada

Publisher: Elsevier

Published: 2011-08-29

Total Pages: 490

ISBN-13: 0080464009

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Tissue engineering is an emerging interdisciplinary field, occupying a major position in the regenerative medicine that aims at restoring lost or damaged tissues and organs with use of cells. Regenerative medicine includes cellular therapy and tissue engineering. In general, the former treats patients by cell infusion alone, while tissue engineering needs biomaterials and growth factors in addition to cells. Biomaterials function in tissue engineering as the scaffold or template for cells to proliferate, differentiate, and produce matrices. Tissue Engineering focuses on the fundamentals (biomaterials, scaffolds, cell cultures, bioreactors, animal models etc.), recent animal and human trials, and future prospects regarding tissue engineering. Almost twenty years have passed since the advent of the tissue engineering, whicht uses cells, scaffolds, and growth factors for regeneration of neotissues. The number of investigations on tissue engineering is still increasing tremendously. Nevertheless, it seems likely that the number of reports describing clinical trials of tissue engineering will remain very limited. Even the studies that apply tissue engineering research to large animals have not been performed yet on a large scale. The major objective of this book is to address this question from a science and technology point of view, and to describe the principles of basic technologies that have currently been developed by numerous research groups. Helps reader understand the key issues required for promotion of clinical trials in tissue engineering Covers in full the issues related to tissue engineering Looking at current technologies in the field

Smart Materials for Tissue Engineering

Smart Materials for Tissue Engineering PDF

Author: Qun Wang

Publisher: Royal Society of Chemistry

Published: 2017

Total Pages: 715

ISBN-13: 1782624848

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In the last couple of decades, research in the area of tissue engineering has witnessed tremendous progress. The focus has been on replacing or facilitating the regeneration of damaged or diseased cell, tissue or organs by applying a biomaterial support system, and a combination of cells and bioactive molecules. In addition new smart materials have been developed which provide opportunities to fabricate, characterize and utilize materials systematically to control cell behaviours and tissue formation by biomimetic topography that closely replicate the natural extracellular matrix. Following on from Smart Materials for Tissue Engineering: Fundamental Principles, this book comprehensively covers the different uses of smart materials in tissues engineering, providing a valuable resource for biochemists, materials scientists and biomedical engineers working in industry and academia.

Collagen Biografts for Tunable Drug Delivery

Collagen Biografts for Tunable Drug Delivery PDF

Author: Rucha Joshi

Publisher: Springer Nature

Published: 2021-01-31

Total Pages: 116

ISBN-13: 3030638170

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This book reviews collagen-based biomaterials that have been applied broadly to tissue engineering and local drug delivery applications and lays out a landscape for developing a multifunctional biograft material from collagen polymers. The book also discusses current shortcomings in collagen based drug delivery opportunities, including poor mechanical properties, rapid proteolytic degradation, and cursory control over physical properties and molecular release profiles. Finally, a review of application of the collagen biograft materials for promoting neovascularization and tissue regeneration is presented, using examples of established in-vivo chicken egg chorioallantoic membrane (CAM) model. Use of heparin for affinity-based vascular endothelial growth factor (VEGF) retention in collagen constructs is also discussed for promoting neovascularization. Reviews state-of-the-art strategies for drug incorporation and retention in collagen​; Covers collagen based material applications for improving vascularization and tissue regeneration; Illustrates how to tailor collagen architecture for soft tissue engineering and controlled drug delivery.

Advances in Tissue Engineering

Advances in Tissue Engineering PDF

Author: Julia M. Polak

Publisher: World Scientific

Published: 2008

Total Pages: 947

ISBN-13: 1848161824

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Advances in Tissue Engineering is a unique volume and the first of its kind to bring together leading names in the field of tissue engineering and stem cell research. A relatively young science, tissue engineering can be seen in both scientific and sociological contexts and successes in the field are now leading to clinical reality. This book attempts to define the path from basic science to practical application. A contribution from the UK Stem Cell Bank and opinions of venture capitalists offer a variety of viewpoints, and exciting new areas of stem cell biology are highlighted. With over fifty stellar contributors, this book presents the most up-to-date information in this very topical and exciting field.

3D Cell Culture

3D Cell Culture PDF

Author: Ranjna C. Dutta

Publisher: CRC Press

Published: 2018-05-11

Total Pages: 212

ISBN-13: 1351378511

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3D cell culture is yet to be adopted and exploited to its full potential. It promises to upgrade and bring our understanding about human physiology to the highest level with the scope of applying the knowledge for better diagnosis as well as therapeutics. The focus of this book is on the direct impact of novel technologies and their evolution into viable products for the benefit of human race. It also describes the fundamentals of cell microenvironment to bring forth the relevance of 3D cell culture in tissue engineering and regenerative medicine. It discusses the extracellular matrix/microenvironment (ECM) and emphasizes its significance for growing cells in 3D to accomplish physiologically viable cell mass/tissue ex vivo. The book bridges the knowledge gaps between medical need and the technological applications through illustrations. It discusses the available models for 3D cell culture as well as the techniques to create substrates and scaffolds for achieving desired 3D microenvironment.

Tissue Engineering

Tissue Engineering PDF

Author: Norbert Pallua

Publisher: Springer Science & Business Media

Published: 2010-12-16

Total Pages: 632

ISBN-13: 3642028241

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Tissue engineering is a multidisciplinary field incorporating the principles of biology, chemistry, engineering, and medicine to create biological substitutes of native tissues for scientific research or clinical use. Specific applications of this technology include studies of tissue development and function, investigating drug response, and tissue repair and replacement. This area is rapidly becoming one of the most promising treatment options for patients suffering from tissue failure. This abundantly illustrated and well-structured guide serves as a reference for all clinicians and researchers dealing with tissue engineering issues in their daily practice.

Collagen

Collagen PDF

Author: Peter Fratzl

Publisher: Springer Science & Business Media

Published: 2008-05-10

Total Pages: 516

ISBN-13: 0387739068

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Not only does this book provide a comprehensive review of current research advances in collagen structure and mechanics, it also explores this biological macromolecule’s many applications in biomaterials and tissue engineering. Readers gain an understanding of the structure and mechanical behavior of type I collagen and collagen-based tissues in vertebrates across all length scales, from the molecular (nano) to the organ (macro) level.

Tissue Engineering

Tissue Engineering PDF

Author: Fouad Sabry

Publisher: One Billion Knowledgeable

Published: 2022-10-05

Total Pages: 405

ISBN-13:

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What Is Tissue Engineering Tissue engineering is a subfield of biomedical engineering that focuses on repairing, maintaining, enhancing, or replacing various kinds of biological tissues through the utilization of a variety of techniques, including cells, engineering, and material science, as well as appropriate biochemical and physicochemical factors. Tissue engineering is not limited to applications that involve cells and tissue scaffolds; rather, it typically involves placing cells on tissue scaffolds in order to form new viable tissue for a medical purpose. However, tissue engineering is not limited to applications involving cells and tissue scaffolds. As a result of its expanding breadth and significance, it is now possible to consider it to be an independent field, despite the fact that it was originally classified as a sub-field of biomaterials. How You Will Benefit (I) Insights, and validations about the following topics: Chapter 1: Tissue engineering Chapter 2: Artificial organ Chapter 3: Regenerative medicine Chapter 4: Organ printing Chapter 5: Knee cartilage replacement therapy Chapter 6: Cardiomyoplasty Chapter 7: Neural tissue engineering Chapter 8: Nerve guidance conduit Chapter 9: Autologous chondrocyte implantation Chapter 10: Nano-scaffold Chapter 11: Fibrin scaffold Chapter 12: Decellularization Chapter 13: 3D bioprinting Chapter 14: 3D cell culture Chapter 15: In vivo bioreactor Chapter 16: Bioartificial heart Chapter 17: Regeneration in humans Chapter 18: Bio-ink Chapter 19: Artificial cartilage Chapter 20: Tissue engineering of heart valves Chapter 21: Artificial ovary (II) Answering the public top questions about tissue engineering. (III) Real world examples for the usage of tissue engineering in many fields. (IV) 17 appendices to explain, briefly, 266 emerging technologies in each industry to have 360-degree full understanding of tissue engineering' technologies. Who This Book Is For Professionals, undergraduate and graduate students, enthusiasts, hobbyists, and those who want to go beyond basic knowledge or information for any kind of tissue engineering.