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Journal of the National Cancer Institute

Author:

Publisher:

Published: 1990

Total Pages: 800

ISBN-13:

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Pamphlets on Protozoology (Kofoid Collection)

Author:

Publisher:

Published: 1908

Total Pages: 472

ISBN-13:

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Managing IBM DB2 10 for z/OS Using the IBM DB2 Administration Tool for z/OS Version 10

Author: Paolo Bruni

Publisher: IBM Redbooks

Published: 2011-04-22

Total Pages: 556

ISBN-13: 0738435406

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Today's business environment has increased in the complexity and rate of change that a database administrator must control. The ability to respond quickly to a changing environment is constantly challenged by the explosion of data growth combined with a decline in an experienced work staff. The IBM® DB2® Administration Tool for z/OS® Version 10 helps you become productive from Day 1 with DB2 10 for z/OS by using performance savings right away, lowering the CPU costs while reducing the batch window. Users experience higher data availability by easily managing online schema changes, including additional columns to indexes to use index-only access. Customers are able to experience higher data availability through simplified recovery operations: Access new functionality in DB2 10 for z/OS to lower costs and improve efficiency both before, during, and after the DB2 migration process. Maximize the performance of your key DB2 business applications to speed their deployment in DB2 10 for z/OS. Improve the productivity and efficiency of your staff when DB2 10 for z/OS is running. This IBM Redbooks® publication highlights the data administration enhancements introduced by DB2 Administration Tool for z/OS Version 10 by providing scenarios of their use with the new functions provided by DB2 10 for z/OS.

Advances in Irrigation Agronomy

Author: M. K. V. Carr

Publisher: Cambridge University Press

Published: 2012-04-05

Total Pages: 377

ISBN-13: 1107012473

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Examines the factors influencing water productivity in nine key plantation crops in the context of increased pressure on water resources.

In Situ Expression of Tumor Immunity

Author: Isaac Witz

Publisher: Springer Science & Business Media

Published: 2013-11-11

Total Pages: 361

ISBN-13: 1468436775

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Because of several valid (and some invalid) reasons, the research field of tumor immunology has been declining in popularity. The Simplistic dogmas, articles of faith, and theories of the late 1960s and early 1970s on the immuno logical mechanisms of the host-tumor interrelationships have frequently been refuted by some of the new developments in cancer biology, cancer biochem istry, and immunology. Furthermore, some of the conventional assays used to monitor "tumor-host immune relations" did not always reflect the host's true clinical situation or his prognosis. Several approaches to immunological interven tion were less successful than expected. In addition, the concept of "immune surveillance," which was basic to many researchers in the field of cancer im munology, seemed to fall apart. Much of the criticism was based on results from solid, well-performed, and well-controlled experiments, but there was also un just criticism based on ill-conceived and badly performed studies, and on misin terpretations of experimental data. There are many misconceptions about the tumor-host relationship. It is very often assumed that tumor immunity, as expressed systemically, is truly reflected at the tumor site. Several studies reported in this volume and elsewhere indicate that such is not always the case. Certain immune effectors may be selectively prevented from reaching the tumor site or the close vicinity of the tumor cells because of mechanical or chemical barriers, whereas others may be selectively attracted to the site by chemotaxis or other mechanisms.

Advances in Tea Agronomy

Author: M. K. V. Carr

Publisher: Cambridge University Press

Published: 2018-01-11

Total Pages: 486

ISBN-13: 110821584X

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Tea is big business. After water, tea is believed to be the most widely consumed beverage in the world. And yet, as productivity increases, the real price of tea declines while labour costs continue to rise. Tea remains a labour intensive industry. With a distinguished career spanning over 50 years and rich experience in diverse crops, Mike Carr is eminently qualified to indulge in an intelligent discourse on tea agronomy. In addition to a comprehensive review of the principal tea growing regions worldwide in terms of structure, productivity and principal constraints, he has attempted to question and seeks to find the associated experimental evidence needed to support current and future crop management practices. The book will assist all those involved in the tea industry to become creative thinkers and to question accepted practices. International in content, it will appeal to practitioners and students from tea growing countries worldwide.

Developability of Biotherapeutics

Author: Sandeep Kumar

Publisher: CRC Press

Published: 2015-11-18

Total Pages: 297

ISBN-13: 1482246155

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Biopharmaceuticals are emerging as frontline medicines to combat several life-threatening and chronic diseases. However, such medicines are expensive to develop and produce on a commercial scale, contributing to rising healthcare costs. Developability of Biotherapeutics: Computational Approaches describes applications of computational and molecular modeling techniques that improve the overall process of discovery and development by removing empiricism. The concept of developability involves making rational choices at the pre-clinical stages of biopharmaceutical drug development that could positively impact clinical outcomes. The book also addresses a general lack of awareness of the many different contributions that computation can make to biopharmaceutical drug development. This informative and practical reference is a valuable resource for professionals engaged in industrial research and development, scientists working with regulatory agencies, and pharmacy, medicine, and life science students and educators. It focuses primarily on the developability of monoclonal antibody candidates, but the principles described can also be extended to other modalities such as recombinant proteins, fusion proteins, antibody drug conjugates and vaccines. The book is organized into two sections. The first discusses principles and applications of computational approaches toward discovering and developing biopharmaceutical drugs. The second presents best practices in developability assessments of early-stage biopharmaceutical drug candidates. In addition to raising awareness of the promise of computational research, this book also discusses solutions required to improve the success rate of translating biologic drug candidates into products available in the clinic. As such, it is a rich source of information on current principles and practices as well as a starting point for finding innovative applications of computation towards biopharmaceutical drug development.