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Circulatory System Dynamics

Author: Abraham Noordergraaf

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 368

ISBN-13: 0323141412

Circulatory System Dynamics reviews cardiovascular dynamics from the analytical viewpoint and indicates ways in which the accumulated knowledge can be expanded and applied to further enhance understanding of the normal mammalian circulation, to ascertain the nature of difficulties associated with disease, and to test the effect of treatment. Comprised of 10 chapters, this volume begins with an overview of the circulatory system, including its anatomy and the trigger for myocardial (heart muscle) contraction. The discussion then turns to measurement of blood pressure using invasive and non-invasive techniques; blood flow measurement, with emphasis on cardiac output and measurement in the microcirculation; the system and pulmonary arterial trees; and pulsatile pressure and flow in pulmonary veins. Subsequent chapters explore microcirculation and the anatomy of the microvasculature; the heart and coronary circulation, paying particular attention to the Frank-Starling mechanism and indices of myocardial "contractility"; and control of blood pressure, peripheral resistance, and cerebral flow. The last two chapters deal with circulatory assistance and the closed cardiovascular system. This book will be of interest to students, practitioners, and researchers in fields ranging from physiology and biology to biochemistry and biophysics.

Cardiovascular System Dynamics

Author: T. Kenner

Publisher: Springer

Published: 2013-11-09

Total Pages: 660

ISBN-13: 1489966935

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Flow Dynamics and Tissue Engineering of Blood Vessels

Author: Arindam Bit

Publisher: Myprint

Published: 2020-12

Total Pages: 316

ISBN-13: 9780750320894

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Flow Dynamics and Tissue Engineering of Blood Vessels explores the physical phenomena of vessel compliance and its influence on blood flow dynamics, as well as the modification of flow structures in the presence of diseases within the vessel wall or diseased blood content. This volume also illustrates the progress of tissue engineering for the intervention of re-engineered blood vessels. Blood vessel organoid models, their controlling aspects, and blood vessels based on microfluidic platforms are illustrated following on from the understanding of flow physics of blood on a similar platform. The purpose of this book is to provide an overview of regenerative medicine and fluid mechanics principles for the management of clinically diseased blood vessels. Authors discuss tissue engineering aspects and computational fluid mechanical principles, and how they can be used to understand the state of blood vessels in diseased conditions. Key Features Computational and experimental fluid dynamics principles have been used to explore the modelling of diseased blood vessels Principles of fluid dynamics and tissue engineering are used to propose innovative designs of bioreactors for blood vessel regeneration Offers experimental analytical studies of blood flow in vessels with pathological conditions Controlling aspects of various parameters while developing blood-vessel bioreactors and organoid models are presented critically, and optimization techniques for these parameters are also provided

Dynamics Of The Vascular System: Interaction With The Heart (Second Edition)

Author: Li John K-j

Publisher: World Scientific

Published: 2018-09-05

Total Pages: 296

ISBN-13: 9814723762

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The first edition of the book was written employing mathematical techniques to formulate the physical principles involved in the structural and functional correlates of the underlying physiology.This current and self-contained second edition updates many of the new findings since its first edition a decade ago. It also includes a new chapter on the 'Interaction with the Heart'. The dynamics of the arterial system, the venous system, the microcirculation and their interaction with the heart are quantitatively described in terms of their structures and functions. Clinical measurements, applications to the cardiovascular field and physiological mechanisms are clearly identified throughout the text. Most importantly, worked examples are provided, such that the readers can appreciate the application aspects of the underlying formulation.

Modeling the Heart and the Circulatory System

Author: Alfio Quarteroni

Publisher: Springer

Published: 2015-04-24

Total Pages: 238

ISBN-13: 3319052306

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The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. The contributions cover a wide range of topics, from the preprocessing of clinical data to the development of mathematical equations, their numerical solution, and both in-vivo and in-vitro validation. They discuss the flow in the systemic arterial tree and the complex electro-fluid-mechanical coupling in the human heart. Many examples of patient-specific simulations are presented. This book is addressed to all scientists interested in the mathematical modeling and numerical simulation of the human cardiocirculatory system.

Cardiovascular Dynamics

Author: Robert Frazer Rushmer

Publisher: Saunders Limited.

Published: 1970

Total Pages: 584

ISBN-13:

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Cardiovascular Fluid Dynamics

Author: D.H. Bergel

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 388

ISBN-13: 0323152694

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Cardiovascular Fluid Dynamics, Volume 1 explores some problems and concepts of mammalian cardiovascular function, with emphasis on experimental studies and methods. It considers pressure measurement in experimental physiology, including the measurements of pulsatile flow, flow velocity, lengths, and dimensions; the use of control theory and systems analysis in cardiovascular dynamics; the application of computer models in cardiovascular research; the meaning and measurement of myocardial contractility; and the consequences of the steady-state analysis of arterial function. Organized into 10 chapters, this volume begins with an overview of the mammalian cardiovascular system and the essential features of cardiovascular function. It then discusses the practical problems associated with the use of pressure transducers in physiological and cardiac laboratories, the challenges involved in pulsatile flow measurement using flowmeters and thermal devices, and the mechanical analysis of the circulatory system. It explains some computer modeling techniques used in investigating the hemodynamics of the cardiovascular system, including the heart and heart muscle; basic concepts of muscle mechanics and the mechanical properties of cardiac muscle; the fluid mechanics of heart valves; and the pressure and flow in large arteries. The book concludes with a chapter on vascular resistance and vascular input impedance. This book is intended for biologists, physical scientists, and others interested in cardiovascular physiology.

Cardiovascular Mathematics

Author: Luca Formaggia

Publisher: Springer Science & Business Media

Published: 2010-06-27

Total Pages: 528

ISBN-13: 8847011523

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Mathematical models and numerical simulations can aid the understanding of physiological and pathological processes. This book offers a mathematically sound and up-to-date foundation to the training of researchers and serves as a useful reference for the development of mathematical models and numerical simulation codes.

Vortex Formation in the Cardiovascular System

Author: Arash Kheradvar

Publisher: Springer Science & Business Media

Published: 2012-02-01

Total Pages: 166

ISBN-13: 1447122887

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Vortex Formation in the Cardiovascular System will recapitulate the current knowledge about the vortex formation in the cardiovascular system, from mechanics to cardiology. This can facilitate the interaction between basic scientists and clinicians on the topic of the circulatory system. The book begins with a synopsis of the fundamentals aspects of fluid mechanics to give the reader the essential background to address the proceeding chapters. Then the fundamental elements of vortex dynamics will be discussed, explaining the conditions for their formation and the rules governing their dynamics. The main equations are accompanied by mathematical models. Cardiovascular vortex formation is first analyzed in physiological, healthy conditions in the heart chambers and in the large arterial vessels. The analysis is initially presented with an intuitive appeal grounded on the physical phenomena and a focus on its clinical significance.In the proceeding chapters, the knowledge gained from either clinical or basic science literature will be discussed. The corresponding mathematical elements will finally be presented to ensure the adequate diligence. The proceeding chapters ensue to the analysis of pathological conditions, when the reader may have developed the ability to recognize normal from abnormal vortex formation phenomenon. Pathological vortex formation represents vortices that develop at sites where normally laminar flow should exist, e.g. stenosis and aneurisms. This analysis naturally leads to the interaction of vortices due to the surgical procedures with respect to prediction of changes in vortex formation. The existing techniques, from medical imaging to numerical simulations, to explore vortex flows in the cardiovascular systems will also be described. The presentations are accompanied by the mathematical definitions can that be understandable for reader without the advanced mathematical background, while an interested reader with more advanced knowledge in mathematics can be referred to references for further quantitative analyses. The book pursues the objective to transfer the fundamental vortex formation phenomena with application to the cardiovascular system to the reader. This book will be a valuable support for physicians in the evaluation of vortex influence on diagnosis and therapeutic choices. At the same time, the book will provide the rigorous information for research scientists, either from medicine and mechanics, working on the cardiovascular circulation incurring with the physics of vortex dynamics.

Cardiovascular System Dynamics

Author: Jan Baan

Publisher: MIT Press (MA)

Published: 1978

Total Pages: 640

ISBN-13:

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This book offers a novel approach to the study of the mammalian cardiovascular system. Instead of focusing on a particular part of the system or on a particular group of techniques, or approaching the system from a particular point of view, it stresses a balanced presentation of ideas: —all the major component parts of the system are discussed, as well as the behavior of the system as an integrated whole —both basic and clinical viewpoints are represented —both detailed analysis and comprehensive synthesis are offered. In addition, trends in modern instrumentation and the use of computers in improving patient care are important and recurrent themes. Spirited discussions of current controversies and philosophies highlight the presentations. The 62 papers in this volume were invited for a major international conference, held in April 1975, which marked the coming of age of this field and led to the founding of the Cardiovascular System Dynamics Society. The conference brought together outstanding researchers in the life sciences (biology, physiology, medicine) and the physical sciences (biophysics, bioengineering) in order to integrate their findings more intricately and to chart the present state and future directions of the field. Since the cardiovascular system has been one of the first areas to receive attention under the newly emerging symbiosis between engineering and medicine, the book also serves a useful secondary purpose as a model of what can be accomplished by such integrated effort. The papers are organized into 12 sections. The first 9 offer a tour of the cardiovascular system, with papers arranged within each section to lead the reader from theoretical to clinical viewpoints. Included are sections on cardiac muscle, coronary circulation, ventricular dynamics, systemic arterial tree, microcirculation, systemic veins, pulmonary vasculature, control mechanisms in specific vascular beds, and cardiovascular system control. The last 3 sections offer tutorial overviews of theoretical and experimental methods applied to the cardiovascular system and of cardiovascular instrumentation and computer analysis.