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Chemistry and Biology of Ellagitannins

Author: Stphane Quideau

Publisher: World Scientific

Published: 2009

Total Pages: 395

ISBN-13: 9812797408

This book is the first of its kind that focuses on the chemistry and biology of ellagitannins, a special class of naturally occurring polyphenols which have so far not received the attention they deserve. These polyphenolic substances are found in many plants, including numerous food sources. They not only exhibit unique structural features that fascinate most chemists who are aware of their existence, but also express remarkable biological activities that have yet to attract the interest of the pharmaceutical industry. This is surprising because ellagitannins have been identified as active principles in traditional Chinese medicines. The principal aim of this book is to set the record straight. Most, if not all, worldwide experts in each aspect of the chemistry and biology of this underestimated class of natural products have contributed to this book. It covers topics such as their structural determination and natural occurrence; the most up-to-date knowledge of their biosynthesis; the current state of the art of their total chemical synthesis; their main physicochemical properties and principal biological activities; their presence in food and beverages; and their related health effects. All together, nine chapters compose this book whose content is placed into historical perspective in a yet inspiring preface written by one of the pioneers in modern polyphenol research, Professor Edwin Haslam. This book will be useful not only to scientists involved in natural product research, but also to lecturers and their students as a source of key references and/or a textbook.

Chemistry and Biology of Ellagitannins

Author: Stephane Quideau

Publisher: World Scientific

Published: 2009

Total Pages: 395

ISBN-13: 9812797416

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Dietary Polyphenols

Author: Francisco A . Tomás-Barberán

Publisher: John Wiley & Sons

Published: 2020-12-15

Total Pages: 560

ISBN-13: 1119563720

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Presents recent research on metabolism and the health effects of polyphenols Consumer interest in the health benefits of many phenolic compounds found in plant foods and derivatives has grown considerably in recent years, giving rise to an increased demand for functional foods. Although preclinical and observational studies have promoted the protective properties of polyphenols for a range of chronic diseases, evidence has shown that most dietary polyphenols have little bioavailability. Once ingested, most of them are metabolized by either the intestinal enzymes or by the gut microbiota and then undergo extensive phase-II metabolism reaching significant concentrations of conjugated metabolites. They remain in the systemic circulation and target systemic tissues where trigger biological effects. The polyphenol-derived metabolites produced in humans are dependent upon the composition of the gut microbiota and the subject genetics. Thus all the metabolites do not show the same biological activity in different individuals. To fully understand the health effects of polyphenols, further clinical investigations are required. Dietary Polyphenols describes the latest findings on the polyphenol metabolism and reviews the current evidence on their health effects and that of their bioavailable metabolites. Emphasizing the importance of interindividual variability and the critical role of gut microbiota, this authoritative volume features contributions from recognized experts in the field, exploring specific families of extractable and non-extractable phenolic compounds that exhibit potential health effects. Topics include structural diversity of polyphenols and distribution in foods, bioavailability and bioaccessibility of phenolics, metabolism, and gastrointestinal absorption of various metabolites and their health effects. This comprehensive volume: Discusses the bioavailability, bioaccessibility, pharmacokinetics studies, and microbial metabolism of different groups of phenolic compounds Examines the interaction between polyphenols and gut microbiota Describes analytical methods for identifying and quantifying polyphenols in foods and biological samples Reviews recent epidemiological and clinical intervention studies showing protective effects of polyphenols Dietary Polyphenols: Metabolism and Health Effects is an important resource for scientists working in the area of dietary polyphenols and health effects, microbiota, and their interaction with other nutritional compounds, and for health professionals, nutritionists, dieticians, and clinical researchers with interest in the role of polyphenols in the prevention and treatment of chronic diseases.

Ellagic Acid

Author: Edmund Brewer

Publisher: Nova Science Publishers

Published: 2016

Total Pages: 0

ISBN-13: 9781634856584

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Ellagic acid is a powerful bioactive polyphenolic compound showing a wide range of biological activities and potential beneficial effects on human health. In this book, Chapter One offers an overview of the main food sources of ellagic acid, its glycosides and ellagitannins. Chapter Two studies two Brazilian fruits rich in ellagic acid: the Camu-camu (M. dubia) and the Jaboticaba (M.cauliflora). Chapter Three also presents a collection of the main sources of ellagic acid, as well as structural and safety features related to its applications on diet. Chapter Four shows the effect of ellagic acid on mitochondrial related diseases with an emphasis on its mitochondrial targeting which contribute to these pathological conditions.

Handbook of Dietary Phytochemicals

Author: Jianbo Xiao

Publisher: Springer

Published: 2021-09-02

Total Pages: 1953

ISBN-13: 9789811541476

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This book summarizes recent advances in the chemistry, bioactivity, nutrition, and functional aspects of dietary phytochemicals, as well as the health and functional aspects of foods rich in phytochemicals. Consisting of forty-four chapters, it discusses the different chemical types of phytochemicals in our diets and food and presents data collected from animal or human experiments that are directly related to human health. Each chapter covers the chemistry, epidemiological study, bioavailability, bioactivity (animal experiments) function in humans and safety, as well as products on the market. Moreover, the more than 200 figures make it easy to grasp the main findings in each area.

Recent Advances in Polyphenol Research, Volume 2

Author: Celestino Santos-Buelga

Publisher: John Wiley & Sons

Published: 2011-01-04

Total Pages: 535

ISBN-13: 1444390406

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Recent Advances in Polyphenol Research Volume 2 Edited by Santos-Buelga, Escribano-Bailon and Lattanzio Plant phenolics are secondary metabolites that constitute one of the most common and widespread groups of substances in plants. Polyphenols have a large and diverse array of beneficial effects on both plants and animals. For example they are famous as antioxidants, hormones, constituents of essential oils and natural neurotransmitters. Sponsored by Groupe Polyphenols, this publication, which is the second volume in this ground-breaking series, is edited by Celestino Santos-Buelga, Maria Teresa Escribano-Bailon, and Vincenzo Lattanzio, who have drawn together an impressive list of internationally respected authors, each providing cutting edge chapters covering some of the major topics of recent research and interest. Information included in this important new addition to the series include the following areas: • Flavonoid chemistry of the leguminosae • Chemistry and biological activity of ellagitannins • Chemistry and function of anthocyanins in plants • An update of chemical pathways leading to new phenolic pigments during wine ageing • Metabolic engineering of the flavonoid pathway • The translation of chemical properties of polyphenols into biological activity with impacts in human health • Plant phenolic compounds controlling leaf movement • Biological activity of phenolics in plants Chemists, biochemists, plant scientists, pharmacognosists and pharmacologists, food scientists and nutritionists will all find this book an invaluable resource. Libraries in all universities and research establishments where these subjects are studied and taught should have copies on their shelves.

Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases

Author: Solomon Habtemariam

Publisher: Academic Press

Published: 2019-06-08

Total Pages: 1180

ISBN-13: 0081029233

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Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases: The Chemical and Pharmacological Basis of their Action focuses on active pharmacological principles that modulate diabetes, associated risk factors, complications and the mechanism of action of widely used anti-diabetic herbal plants—rather than just the nutritional composition of certain foods. The book provides up-to-date information on acclaimed antidiabetic super fruits, spices and other food ingredients. Sections cover diabetes and obesity at the global level, the physiological control of carbohydrate and lipid metabolism, the pathophysiology of type-2 diabetes, the chemistry and pharmacology of a variety of spices, and much more. This book will be invaluable for research scientists and students in the medical and pharmaceutical sciences, medicinal chemistry, herbal medicine, drug discovery/development, nutrition science, and for herbal practitioners and those from the nutraceutical and pharm industries. Provides background knowledge on type-2 diabetes and its pathophysiology and therapeutic targets down to the molecular level Explores, in detail, the chemistry or secondary metabolites of the indicated foods that potentially modify diabetes and/or associated diseases Examines the pharmacological findings on medicinal foods, including available clinical trials

Plant Polyphenols

Author: Richard W. Hemingway

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 1027

ISBN-13: 1461534763

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This book was developed from the proceedings of the 2nd North American Tan nin Conference held in Houghton, Michigan, June, 1991. The objective of this con ference was to bring together people with a common interest in plant polyphenols and to promote interdisciplinary interactions that will lead to a bet ter understand ing of the importance of these substances. Another objective of this conference was to extend the 'tannin family' by making special efforts to encourage participation by scientists outside the United States, obtain more coverage of the hydrolyzable tannins, and further broaden the scope of coverage from the initial concentration on forestry and forest products. Com parison of the contents of this book with 'Chemistry and Significance of Condensed Tannins' that resulted from the proceedings of the 1st North American Tannin Conference shows the degree that these objectives were met. In developing the second conference, care was taken to assure that this book extends rather than duplicates the coverage of the first conference. Therefore, the two books should be taken together to obtain an up to date coverage of the broad area of chemistry and significance of plant polyphenols. Our thanks go to the authors who so kindly contributed chapters and so pa tiently responded to our requests. We thank the Conference Assistance Staff of Michigan Technological University for their help in planning and conducting the conference.

Tannins

Author: Alfredo Aires

Publisher: BoD – Books on Demand

Published: 2020-01-08

Total Pages: 150

ISBN-13: 1789847966

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Tannins are one of the polyphenols group found in plants and are mainly studied because of their structural properties and bioactive behavior. Every year new findings concerning their properties and functions are made, and today concerns are mainly focused on how they can be used efficiently in the wood, food, textile, health, and pharmaceutical industries. Thus, the aim of this book is to present the most updated information on the structural properties of tannins, their food sources and variations, biological properties, and health, among other important issues. In addition, the most recent methods used for their isolation, quantifications, and industrial applications will also be covered.

Special Issue Dedicated to Late Professor Takuo Okuda

Author: Hideyuki Ito

Publisher: MDPI

Published: 2019-04-30

Total Pages: 318

ISBN-13: 3038978345

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Antioxidative polyphenols represented by tannins and flavonoids are rich in numerous food sources and traditional natural medicines and currently attracting increased attention in health care and food industries because of their multiple biological activities that are favorable to human health. Commemorating the outstanding achievements on tannins by Dr. Takuo Okuda on the occasion of his passing away in December 2016, his colleagues, friends, and worldwide experts of polyphenol research have contributed 18 papers on their recent study to the Special Issue of Molecules. This book is its reprinted form. This covers reviews of structural features, historical usages, and biological activities of unique class of ellagitannins and condensed tannins, and original articles on the most up-to-date findings on the anticancer effect of green tea catechins, the antivirus effect of tannins comparing with the clinically used drugs, the analytical method of ellagitannins using quantitative NMR, the chemical structures of Hydrangea-blue complex (pigment) and condensed tannins in Ephedra sinica and purple prairie clover, and the relationship of condensed tannins in legumes and grape-marc with methane production in the in vitro ruminant system, and others. This book will be useful to natural product chemists and also to researchers in pharmaceutical and/or food industry.