-PDF Download- Carnitine Biosynthesis Metabolism And Functions EBOOK

Carnitine Biosynthesis Metabolism, And Functions

Author: Rene Frenkel

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 377

ISBN-13: 0323153402

Carnitine Biosynthesis, Metabolism, and Functions contains the proceedings of the Virginia Lazenby O'Hara Biochemistry Symposium held in Dallas, Texas, from March 31 to April 1, 1979. The papers explore all aspects of carnitine metabolism, including its biosynthesis, regulation, transport, and functions. Comprised of 24 chapters divided into four sections, this book opens with a brief review of the situation which led to the discovery of carnitine as a vitamin and its role in acetylation. The discussion then turns to the chemistry and biosynthesis of carnitine in Neurospora crassa, rat kidney, and humans. The purification of enzymes involved in the conversion of trimethyllysine to trimethylaminobutyrate is also considered. The following chapters examine carnitine transport across the plasma membrane; formation and utilization of isobutyrylcarnitine; regulation of blood carnitine and carnitine acyltransferases in the perinatal period; and inhibitors of carnitine transport and metabolism. The final section is devoted to medical and clinical aspects of carnitine, touching on topics such as the possible causes and effects of carnitine deficiency in humans; carnitine deficiency in cirrhosis; protective effects of L-carnitine on ischemic heart; and changes in carnitine-linked metabolism during ischemia, thermal injury, and shock. This monograph will be a useful resource for biochemists and those interested in the physiological roles of carnitine.

Carnitine Metabolism and Human Nutrition

Author: Benjamin T. Wall

Publisher: CRC Press

Published: 2016-04-19

Total Pages: 184

ISBN-13: 1466554274

DOWNLOAD EBOOK →

Carnitine Metabolism and Human Nutrition offers a contemporary and in-depth look at the biological effects of carnitine metabolism and its application to clinical and sports nutrition, based on decades of robust scientific enquiry. It gathers and distills key results of the last 20 years of carnitine research to provide an invaluable reference tool

Food Components to Enhance Performance

Author: Institute of Medicine

Publisher: National Academies Press

Published: 1994-02-01

Total Pages: 560

ISBN-13: 030905088X

DOWNLOAD EBOOK →

The physiological or psychological stresses that employees bring to their workplace affect not only their own performance but that of their co-workers and others. These stresses are often compounded by those of the job itself. Medical personnel, firefighters, police, and military personnel in combat settingsâ€"among othersâ€"experience highly unpredictable timing and types of stressors. This book reviews and comments on the performance-enhancing potential of specific food components. It reflects the views of military and non-military scientists from such fields as neuroscience, nutrition, physiology, various medical specialties, and performance psychology on the most up-to-date research available on physical and mental performance enhancement in stressful conditions. Although placed within the context of military tasks, the volume will have wide-reaching implications for individuals in any job setting.

Clinical Aspects of Human Carnitine Deficiency

Author: Peggy R. Borum

Publisher: Pergamon

Published: 1986

Total Pages: 296

ISBN-13:

DOWNLOAD EBOOK →

Abstract: The proceedings of a 1985 international symposium for food scientists, clinicians, and nutritionists reviews the current status of research in the carnitine field and the current status of medical care of patients who may benefit from treatment with exogenous carnitine. The text includes 15 detailed reviews grouped among 5 major areas, with numerous abstracts of poster presentations appended to each of these 5 areas. The 5 areas include: carnitine metabolism and function in normal subjects; assay methods for carnitine, carnitine-biosynthetic enzymes, and enzymes that utilize carnitine as a substrate; human carnitine deficiency; deficiencies of enzymes that use carnitine as a substrate; and situations in which carnitine deficiency is secondary to chronic disease states. The use of carnitine supplementation also is discussed. Five workshop summaries concerning the analysis, deficiency diagnosis, and supplementation of carnitine are appended.

Studies on Carnitine and Related Metabolism in End Stage Renal Disease

Author: Lavon L. Bartel

Publisher:

Published: 1979

Total Pages: 374

ISBN-13:

DOWNLOAD EBOOK →

Industrial Biotechnology of Vitamins, Biopigments, and Antioxidants

Author: Erick J. Vandamme

Publisher: John Wiley & Sons

Published: 2016-04-25

Total Pages: 580

ISBN-13: 3527337342

DOWNLOAD EBOOK →

Vitamins are a group of physiologically very important, chemically quite complex organic compounds, that are essential for humans and animals. Some vitamins and other growth factors behave as antioxidants, while some can be considered as biopigments. As their chemical synthesis is laborious, their biotechnology-based synthesis and production via microbial fermentation has gained substantial interest within the last decades. Recent progress in microbial genetics and in metabolic engineering and implementation of innovative bioprocess technology has led to a biotechnology-based industrial production of many vitamins and related compounds. Divided into three sections, this volume covers: 1. water-soluble vitamins 2. fat-soluble vitamin compounds and 3. other growth factors, biopigments, and antioxidants. They are all reviewed systematically: from natural occurrence and assays, via biosynthesis, strain development, to industrially-employed biotechnological syntheses and applications.

Nutrient Metabolism

Author: Martin Kohlmeier

Publisher: Elsevier

Published: 2003-10-01

Total Pages: 841

ISBN-13: 0080537898

DOWNLOAD EBOOK →

Nutrient Metabolism defines the molecular fate of nutrients and other dietary compounds in humans, as well as outlining the molecular basis of processes supporting nutrition, such as chemical sensing and appetite control. It focuses on the presentation of nutritional biochemistry; and the reader is given a clear and specific perspective on the events that control utilization of dietary compounds. Slightly over 100 self-contained chapters cover all essential and important nutrients as well as many other dietary compounds with relevance for human health. An essential read for healthcare professionals and researchers in all areas of health and nutrition who want to access the wealth of nutrition knowledge available today in one single source. Key Features * Highly illustrated with relevant chemical structures and metabolic pathways * Foreword by Steven Zeisel, Editor-in-chief of the Journal of Nutritional Biochemistry * First comprehensive work on the subject

The Carnitine System

Author: J.W. de Jong

Publisher: Springer

Published: 2012-01-11

Total Pages: 400

ISBN-13: 9789401041225

DOWNLOAD EBOOK →

In the last few years, derivatives of L-carnitine, such as acetyl-L-carnitine and propionyl-L-carnitine, have been made available to doctors for treatment of specific pathologies. The effects of this family of related carnitine compounds on cardiovascular systems and diseases constitute the major issue addressed in this volume. Although several books on carnitine have been published, a treatise focusing on experimental and clinical aspects of the carnitine family and cardiovascular diseases was lacking. The present book provides the reader with a concise update in this field. The information collected from experts on various aspects of the fascinating compound, carnitine, will be useful for both clinicians and basic scientists.

The Heterogeneity of Cancer Metabolism

Author: Anne Le

Publisher: Springer

Published: 2018-06-26

Total Pages: 186

ISBN-13: 331977736X

DOWNLOAD EBOOK →

Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Nutritional Epigenomics

Author:

Publisher: Academic Press

Published: 2019-07-20

Total Pages: 478

ISBN-13: 0128173106

DOWNLOAD EBOOK →

Nutritional Epigenomics offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition’s role in the epigenomic regulation of disease, health and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet’s role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes. Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders. Diet-gut microbiome interactions in the epigenomic regulation of disease are also discussed, as is the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease. Empowers the reader to employ nutritional epigenomics approaches in their own research Discusses the latest topics in nutritional epigenomics in the regulation of aging, circadian rhythm, inheritance and fetal development, as well as metabolism and disease Offers a full grounding in epigenetic reprogramming and nutritional intervention in the treatment and prevention of disease, as informed by population-based studies