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Cardiovascular and Metabolic Comorbidities in Pituitary Disorders

Author: Pawel Krzesinski

Publisher: Frontiers Media SA

Published: 2024-06-12

Total Pages: 108

ISBN-13: 2832550347

Pituitary disorders may be associated with an increased risk of cardiovascular and metabolic complications and, in consequence, increased mortality. Excessive secretion of pituitary hormones provokes functional and systemic abnormalities which can be manifested by cardiovascular complications such as eg. arterial hypertension, heart failure, arrhythmia, as through metabolic disturbances, including obesity and diabetes. Subclinical effects of pituitary diseases, such as cardiac and vascular dysfunction, also modifies prognosis but due to its asymptomatic course are frequently diagnosed with significant time delay. Even successful surgery and pharmacological treatment of pituitary disorders do not guarantee that metabolic and cardiovascular comorbidities can be completely resolved after primary disease remission. This Research Topic aims to provide insights into the cross-talk between pituitary and cardiometabolic disorders in respect to effective diagnosis and targeted therapy. We also especially welcome studies that advance our knowledge on molecular mechanisms and pathogenic pathways explaining these phenomena. Another issue that still needs clarification is an effective model of interdisciplinary care focused on holistic approach to patients with pituitary disorders. We would like to turn on a light of attention towards the importance of psychological, dietary, and rehabilitation care. We aim to collect the up-to-date studies presenting novel results and future perspectives in this area. In this Research Topic, we welcome the submission of original research, reviews, and expert opinions, that include but are not limited to the following areas in pituitary disorders: • prevalence of cardiovascular and metabolic comorbidities • molecular mechanisms and pathogenic pathways of cardiovascular and metabolic complications • novel diagnostic tools and biochemical markers to detect early cardiovascular and metabolic complications • individualized treatment of cardiovascular and metabolic complications • reversibility of cardiovascular and metabolic abnormalities after biochemical control of primary endocrine dysfunction • optimal model of interdisciplinary care • diet, psychological support, rehabilitation

The Hypothalamic-Pituitary-Adrenal Axis in Health and Disease

Author: Eliza B. Geer

Publisher: Springer

Published: 2016-12-01

Total Pages: 327

ISBN-13: 3319459503

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Cushing ́s syndrome is a rare disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function, and psychiatric disease, all of which severely reduce quality of life and life expectancy. This book reviews the role of cortisol in the human body, focusing on the effects of excess cortisol due to Cushing’s syndrome as well as the role of the HPA axis in metabolism, inflammation, and neuropsychiatric function. The volume will cover basic mechanistic data, clinical outcomes data, and novel therapies. Also discussed are everything from abnormalities of the HPA axis, to the role of the HPA axis in the development of neuropsychiatric disorders and metabolic disorders, to new definitions of Cushing’s remission and recurrence. The Hypothalamic Pituitary Adrenal Axis in Health and Disease will provide a comprehensive and multi-disciplinary review of the pathophysiology and outcomes of excess cortisol in the human body and brain as well as the role of the HPA axis in other disease states.

Growth Hormone And The Heart

Author: Andrea Giustina

Publisher: Springer Science & Business Media

Published: 2000-11-30

Total Pages: 538

ISBN-13: 9780792372127

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Growth Hormone and the Heart endeavors to bring together knowledge that has been accumulated in the area of GH and the heart, from basic to clinical studies, by research groups working on this topic throughout the world. Lessons from different experimental models and from several human diseases (acromegaly, adult GH deficiency, heart failure) suggest to endocrinologists and cardiologists that GH may not only have a role in the physiology and pathophysiology of heart function, but that GH itself may have a place in the treatment of primary heart diseases (such as dilated cardiomyopathy) or of cardiac complications of hypopituitarism. Growth Hormone and the Heart will be a useful update of the research produced in the field of cardiovascular endocrinology. The Editors also hope that this book will serve as the primary step in the recognition of the wide physiological and clinical significance of GH and heart interactions.

Pituitary Disorders, An Issue of Endocrinology and Metabolism Clinics of North America

Author: Niki Karavitaki

Publisher: Elsevier Health Sciences

Published: 2020-09-01

Total Pages: 241

ISBN-13: 0323755038

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This issue of Endocrinology and Metabolism Clinics will cover Pituitary Disorders. Curated by Dr. Niki Karavitaki, this issue will explore topics in the field that are relevant for practicing clinicians. This issue is one of four selected each year by the series Consulting Editor, Adriana G. Ioachimescu. The volume will include articles on: Epidemiology of pituitary disease, Advances in the imaging of pituitary tumours, WHO 2017 classification of pituitary tumours, Cancer immunotherapy and pituitary function, Advances in the medical treatment of Cushing’s disease, Nelson’s syndrome, Update on genetics of pituitary tumours, Dopamine agonists for pituitary tumours: benefits and risks, Acromegaly: Update on management and long-term morbidities, Endoscopic surgery for pituitary tumours, Aggressive pituitary adenomas and carcinomas, Diabetes insipidus: an update, Management of hypothalamic obesity, and Pituitary Centers of Excellence.

Hormonal and Metabolic Abnormalities in Heart Failure Patients: Pathophysiological Insights and Clinical Relevance, An Issue of Heart Failure Clinics, Ebook

Author: Pasquale Perrone Filardi

Publisher: Elsevier Health Sciences

Published: 2019-05-11

Total Pages:

ISBN-13: 0323678009

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This issue of Heart Failure Clinics, Guest Edited by Dr. Pasquale Perrone Filardi, will focus on Hormonal and Metabolic Abnormalities in Heart Failure Patients. This issue is one of four selected for the year by the series Consulting Editor, Eduardo Bossone. Topics include, but are not limited to, Glucose metabolism abnormalities in heart failure patients, Diabetic cardiomyopathy, New oral antidiabetics in chronic heart failure, Metabolic syndrome and heart failure, Eritropoietin anemia and iron vs. exercise capacity in chronic heart failure, Prognostic value of hormonal abnormalities in heart failure patients, Hormonal Replacement Therapy in Heart Failure, The management of thyroid abnormalities in chronic heart failure, Acromegaly and heart failure, Beta-receptor signaling and heart failure, and Evaluation of cardiac metabolism by magnetic resonance spectroscopy in heart failure.

Metabolic Syndrome consequent to Endocrine Disorders

Author: V. Popovic

Publisher: Karger Medical and Scientific Publishers

Published: 2018-04-05

Total Pages: 174

ISBN-13: 3318063355

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Hormonal dysfunction can have a major and often complex impact on all key components of the metabolic syndrome. This book comprises state-of-the-art reviews on the subject written by recognized experts in the field of endocrinology. Each chapter covers specific manifestations associated with the metabolic syndrome in classic endocrine diseases. Compelling questions are highlighted and future directions presented. The topics covered include hypopituitarism, adrenal insufficiency, acromegaly, glucocorticoid excess, androgen excess, hypogonadism, prolactin, and thyroid and parathyroid hormone abnormalities. This book is meant to inspire subsequent research related to metabolic complications in endocrine diseases, thus enabling early detection as well as prompt and appropriate management.

Comorbidity of Mental and Physical Disorders

Author: N. Sartorius

Publisher: Karger Medical and Scientific Publishers

Published: 2014-11-26

Total Pages: 202

ISBN-13: 3318026042

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This publication presents evidence about the magnitude and severe consequences of comorbidity of mental and physical illnesses from a personal and societal perspective. Leading experts address the huge burden of co-morbidity to the affected individual as well as the public health aspects, the costs to society and interaction with factors stemming from the context of socioeconomic developments. The authors discuss the clinical challenge of managing cardiovascular illnesses, cancer, infectious diseases and other physical illness when they occur with a range of mental and behavioral disorders, including substance abuse, eating disorders and anxiety. Also covered are the organization of health services, the training of different categories of health personnel and the multidisciplinary engagement necessary to prevent and manage comorbidity effectively. The book is essential reading for general practitioners, internists, public health specialists, psychiatrists, cardiologists, oncologists, medical educationalists and other health care professionals.

Cardiovascular Diseases and Depression

Author: Bernhard T. Baune

Publisher: Springer

Published: 2016-08-01

Total Pages: 533

ISBN-13: 3319324802

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The world is witnessing a burgeoning global epidemic of chronic cerebro- and cardiovascular disease and depression disorders. The reader will find this comprehensive book to be a long-needed, up-to-date knowledge base on these increasingly recognized comorbid conditions that have long-term consequences for individual function and well-being and society in general. This comprehensive book outlines the complex and bidirectional relationship between various types of depression and cerebro- and cardiovascular diseases. It is written by a range of experts in the field, including psychiatrists, cardiologists, neuroscientists, psychologists, and epidemiologists, with the aim of presenting and discussing the most recent evidence on the pathophysiology, neurobiology, and clinical presentation of these common and disabling comorbid conditions and the available pharmacological, psychological, and behavioral interventions. By elucidating the underlying clinical and neurobiological mechanisms in the brain and the rich interplay between the body and the brain biology, the book brings together the latest knowledge of this overlapping area in Psychiatry and Cardiology. The clear descriptions of evidence-based approaches to clinical treatment ensure that it will serve as both an up-to-date overview and a future guide for practicing clinicians and graduate students.

Bottom-Up Approach: a Route for Effective Multi-modal Imaging of Tumors

Author: Min Wu

Publisher: Frontiers Media SA

Published: 2022-02-21

Total Pages: 295

ISBN-13: 2889744531

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Eating Disorders and Obesity in Children and Adolescents

Author: Johannes Hebebrand

Publisher: Elsevier Health Sciences

Published: 2018-12-07

Total Pages: 400

ISBN-13: 0323548539

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Get a quick, expert overview of best practices for diagnosis and treatment of eating disorders in children and adolescents. This concise resource by Drs. Johannes Hebebrand and Beate Herpertz-Dahlmann provides psychiatrists and pediatricians with current information in this increasingly important field, including practical sections on developmental aspects of eating disorders, symptomology, epidemiology, etiology and pathyphysiology, treatment and outcomes, and prevention. Discusses general concepts for feeding, eating, and weight disorders; body weight and composition, appetite regulation, and the emergence of body perception and image. Covers genetics of eating and weight disorders, influence of hormones, intergenerational effects, and food addiction. Includes information on cognitive behavioral therapy, family-based therapies, early intervention, pharmacotherapy, bariatric surgery, and other treatments. Consolidates today’s available information on this timely topic into a single convenient resource.