Bone Health and Osteoporosis

Bone Health and Osteoporosis PDF

Author: United States Public Health Service

Publisher:

Published: 2004-12

Total Pages: 0

ISBN-13: 9781410219275

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This first-ever Surgeon General's Report on bone health and osteoporosis illustrates the large burden that bone disease places on our Nation and its citizens. Like other chronic diseases that disproportionately affect the elderly, the prevalence of bone disease and fractures is projected to increase markedly as the population ages. If these predictions come true, bone disease and fractures will have a tremendous negative impact on the future well-being of Americans. But as this report makes clear, they need not come true: by working together we can change the picture of aging in America. Osteoporosis, fractures, and other chronic diseases no longer should be thought of as an inevitable part of growing old. By focusing on prevention and lifestyle changes, including physical activity and nutrition, as well as early diagnosis and appropriate treatment, Americans can avoid much of the damaging impact of bone disease and other chronic diseases. This Surgeon General's Report brings together for the first time the scientific evidence related to the prevention, assessment, diagnosis, and treatment of bone disease. More importantly, it provides a framework for moving forward. The report will be another effective tool in educating Americans about how they can promote bone health throughout their lives. This first-ever Surgeon General's Report on bone health and osteoporosis provides much needed information on bone health, an often overlooked aspect of physical health. This report follows in the tradition of previous Surgeon Generals' reports by identifying the relevant scientific data, rigorously evaluating and summarizing the evidence, and determining conclusions.

Bone and Development

Bone and Development PDF

Author: Felix Bronner

Publisher: Springer Science & Business Media

Published: 2010-03-10

Total Pages: 321

ISBN-13: 1848828225

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This, the sixth volume in a series of reviews centered on a single major topic in osteopathy, examines pediatric bone development. It covers problematic aspects from basic skeletal growth to tooth mineralization, and synthesizes theory and practice.

Bones and Cartilage

Bones and Cartilage PDF

Author: Brian K. Hall

Publisher: Academic Press

Published: 2014-12-23

Total Pages: 911

ISBN-13: 0124166857

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Bones and Cartilage provides the most in-depth review and synthesis assembled on the topic, across all vertebrates. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage develop in embryos and are maintained in adults, how bone is repaired when we break a leg, or regenerates when a newt grows a new limb, or a lizard a new tail. The second edition of Bones and Cartilage includes the most recent knowledge of molecular, cellular, developmental and evolutionary processes, which are integrated to outline a unified discipline of developmental and evolutionary skeletal biology. Additionally, coverage includes how the molecular and cellular aspects of bones and cartilage differ in different skeletal systems and across species, along with the latest studies and hypotheses of relationships between skeletal cells and the most recent information on coupling between osteocytes and osteoclasts All chapters have been revised and updated to include the latest research. Offers complete coverage of every aspect of bone and cartilage, with updated references and extensive illustrations Integrates development and evolution of the skeleton, as well a synthesis of differentiation, growth and patterning Treats all levels from molecular to clinical, embryos to evolution, and covers all vertebrates as well as invertebrate cartilages Includes new chapters on evolutionary skeletal biology that highlight normal variation and variability, and variation outside the norm (neomorphs, atavisms) Updates hypotheses on the origination of cartilage using new phylogenetic, cellular and genetic data Covers stem cells in embryos and adults, including mesenchymal stem cells and their use in genetic engineering of cartilage, and the concept of the stem cell niche

Cartilage and Bone Development and Its Disorders

Cartilage and Bone Development and Its Disorders PDF

Author: C. Camacho-Hübner

Publisher: Karger Medical and Scientific Publishers

Published: 2011-08-23

Total Pages: 132

ISBN-13: 3805597932

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In systemic childhood diseases, including cancer, gastrointestinal, pulmonary and cardiac disorders, childhood growth is severely impaired. In addition, almost 400 known genetic diseases inhibit the ability of the growth plate to form new bone, leaving affected children with growth failure and bony deformities which can severely impact their quality of life and may lead to morbidity and early mortality.This book provides a comprehensive review of bone and cartilage development, growth and disease. Focusing on novel treatment strategies, regulatory signals and molecular mechanisms are discussed in relation to the diseases affecting them. Furthermore, novel methodologies in bone and cartilage research based on recent advances in skeletal stem cell biology, cartilage tissue engineering and allele-specific gene silencing is covered.Providing insight into the basic mechanisms of bone growth, structure and metabolism, research methodology, as well as discussing the clinical management of related diseases, this book is of particular value to physicians with a special interest in bone and cartilage biology; in particular endocrinologists and pediatric endocrinologists that see patients with growth disorders, osteoporosis, osteogenesis imperfecta, and skeletal dysplasias.

Pediatric Bone

Pediatric Bone PDF

Author: Francis H. Glorieux

Publisher: Academic Press

Published: 2011-09-28

Total Pages: 885

ISBN-13: 0123820405

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Pediatric osteology, a medical specialty that has come of age, has contributed to the understanding of adult bone diseases as well. This second edition reference updates the 2003 edition with more emphasis on management as well as new and revised contributions. Thirty chapters present basic information regarding bone development, tools and techniques for evaluation (including a new chapter on radiographic imaging), and the specifics of various diseases. The three editors are affiliated as follows: Francis H. Glorieux (McGill U., Canada), John M. Pettifor (Chir Hani Baragwanath Hospital, South Africa), and Harald Juppner (Harvard Medical School, US). Academic Press is an imprint of Elsevier. Annotation ©2012 Book News, Inc., Portland, OR (booknews.com).

Bone Pathology

Bone Pathology PDF

Author: Jasvir S. Khurana

Publisher: Springer Science & Business Media

Published: 2009-12-02

Total Pages: 419

ISBN-13: 1597453471

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Bone Pathology is the second edition of the book, A Compendium of Skeletal Pathology that published 10 years ago. Similar to the prior edition, this book complements standard pathology texts and blends new but relatively established information on the molecular biology of the bone. Serving as a bench-side companion to the surgical pathologist, this new edition reflects new advances in our understanding of the molecular biology of bone. New chapters on soft-tissue sarcomas and soft-tissue tumors have been added as well as several additional chapters such as Soft-tissue pathology and Biomechanics. The volume is written by experts who are established in the field of musculoskeletal diseases. Bone Pathology is a combined effort from authors of different specialties including surgeons, pathologists, radiologists and basic scientists all of whom have in common an interest in bone diseases. It will be of great value to surgical pathology residents as well as practicing pathologists, skeletal radiologists, orthopedic surgeons and medical students.

Developmental Juvenile Osteology

Developmental Juvenile Osteology PDF

Author: Craig Cunningham

Publisher: Academic Press

Published: 2016-07-26

Total Pages: 632

ISBN-13: 012382107X

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Developmental Juvenile Osteology was created as a core reference text to document the development of the entire human skeleton from early embryonic life to adulthood. In the period since its first publication there has been a resurgence of interest in the developing skeleton, and the second edition of Developmental Juvenile Osteology incorporates much of the key literature that has been published in the intervening time. The main core of the text persists by describing each individual component of the human skeleton from its embryological origin through to its final adult form. This systematic approach has been shown to assist the processes of both identification and age estimation and acts as a core source for the basic understanding of normal human skeletal development. In addition to this core, new sections have been added where there have been significant advances in the field. Identifies every component of the juvenile skeleton, by providing a detailed analysis of development and ageing and a detailed description of each bone in four ways: adult bone, early development, ossification and practical notes New chapters and updated sections covering the dentition, age estimation in the living and bone histology An updated bibliography documenting the research literature that has contributed to the field over the past15 years since the publication of the first edition Heavily illustrated, including new additions

Osteogenesis and Bone Regeneration

Osteogenesis and Bone Regeneration PDF

Author: Haisheng Yang

Publisher: BoD – Books on Demand

Published: 2019-04-24

Total Pages: 143

ISBN-13: 1789857678

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Osteogenesis is a core component of the skeletal system and depends on the well-coordinated proliferation and differentiation of osteogenic cells. Multiple signaling pathways and transcriptional factors tightly regulate the process of osteogenesis. Any abnormities in bone formation could cause severe disorders such as osteogenesis imperfecta and osteoporosis. Bone regeneration, a complex and well-orchestrated physiological process of osteogenesis, remains a medical challenge in the field of orthopedics and maxillofacial surgery. This book provides an overview of the current developments in osteogenesis and bone regeneration, including molecular and cellular mechanisms, physical therapies (low-level laser, distraction osteogenesis), biological therapies (mesenchymal stem cells, stem cell derived exosomes, inflammatory factor, Chinese medicine), as well as tissue engineering approaches promoting bone regeneration by targeting osteogenesis.

Bone

Bone PDF

Author: Brian K. Hall

Publisher: CRC Press

Published: 1992-11-09

Total Pages: 376

ISBN-13: 9780849388279

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Bone: A Treatise is a series of seven volumes devoted to providing the most up-to-date, comprehensive, and authoritative coverage of all aspects of bone. Seventy-four chapters have been written by 127 respected authors, all of whom are actively engaged in basic, applied, and clinical bone research. The seven volumes in this unique series are organized thematically; each volume integrates structure, function, biochemistry, metabolism, and the molecular and clinical aspects of a particular aspect of the biology of bone. Bone-forming cells are treated in Volume I. Bone resorbing cells are covered in Volume II. Volumes III and IV examine the extracellular matrix of bone, with Volume III concentrating on the structure of bone matrix and on bone-specific proteins, while Volume IV focuses on the mineralization (calcification) of that matrix. Volume V addresses the repair and regeneration of bone. Volumes VI and VII explore bone growth and development.