Blood Vessel Wall and Thrombosis

Blood Vessel Wall and Thrombosis PDF

Author: Taylor & Francis Group

Publisher: Routledge

Published: 2020-12

Total Pages: 332

ISBN-13: 9780367262075

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First published in 1988, this 2 volume set presents the latest, authoritative information on the regulatory role of the blood vessel wall on the process of hemostasis in health and disease.

Blood Vessels

Blood Vessels PDF

Author: S. Effert

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 176

ISBN-13: 3642664717

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Platelet-Vessel Wall Interactions in Hemostasis and Thrombosis

Platelet-Vessel Wall Interactions in Hemostasis and Thrombosis PDF

Author: Rolando E. Rumbaut

Publisher: Biota Publishing

Published: 2010-02-01

Total Pages: 77

ISBN-13: 1615040404

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Platelets are essential mediators of the physiologic process of hemostasis and pathologic thrombosis. While platelets do not interact with vascular walls under normal conditions, vascular injury or inflammation result in a coordinated series of events including platelet adhesion, aggregation, and promotion of coagulation. In this review, we describe the primary mechanisms involved in these responses in various vascular beds of both macro- and microvessels, and outline key unresolved aspects of these important interactions.

Mechanisms of Vascular Disease

Mechanisms of Vascular Disease PDF

Author: Robert Fitridge

Publisher: University of Adelaide Press

Published: 2011

Total Pages: 589

ISBN-13: 1922064009

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New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Platelets, Thrombosis and the Vessel Wall

Platelets, Thrombosis and the Vessel Wall PDF

Author: Michael C Berndt

Publisher: CRC Press

Published: 2003-09-02

Total Pages: 471

ISBN-13: 0203304322

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Platelets, Thrombosis and the Vessel Wall aims to highlight the key areas of platelet function in the regulation of haemostasis and thrombosis and covers areas such as platelet production, interaction of platelets with leucocytes, mechanisms of cross-talk between platelets, leukocytes, and endothelium. The two major clinical causes of thrombosis, anti-phospholipid antibodies and genetic predisposition, are also addressed.

The Endothelium

The Endothelium PDF

Author: Michel Félétou

Publisher: Morgan & Claypool Publishers

Published: 2011

Total Pages: 309

ISBN-13: 1615041230

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The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References