Biostatistical Design and Analysis Using R

Biostatistical Design and Analysis Using R PDF

Author: Dr Murray Logan

Publisher: John Wiley & Sons

Published: 2011-09-20

Total Pages: 578

ISBN-13: 144436247X

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R — the statistical and graphical environment is rapidly emerging as an important set of teaching and research tools for biologists. This book draws upon the popularity and free availability of R to couple the theory and practice of biostatistics into a single treatment, so as to provide a textbook for biologists learning statistics, R, or both. An abridged description of biostatistical principles and analysis sequence keys are combined together with worked examples of the practical use of R into a complete practical guide to designing and analyzing real biological research. Topics covered include: simple hypothesis testing, graphing exploratory data analysis and graphical summaries regression (linear, multi and non-linear) simple and complex ANOVA and ANCOVA designs (including nested, factorial, blocking, spit-plot and repeated measures) frequency analysis and generalized linear models. Linear mixed effects modeling is also incorporated extensively throughout as an alternative to traditional modeling techniques. The book is accompanied by a companion website www.wiley.com/go/logan/r with an extensive set of resources comprising all R scripts and data sets used in the book, additional worked examples, the biology package, and other instructional materials and links.

Biostatistics with R

Biostatistics with R PDF

Author: Babak Shahbaba

Publisher: Springer Science & Business Media

Published: 2011-12-15

Total Pages: 355

ISBN-13: 1461413028

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Biostatistics with R is designed around the dynamic interplay among statistical methods, their applications in biology, and their implementation. The book explains basic statistical concepts with a simple yet rigorous language. The development of ideas is in the context of real applied problems, for which step-by-step instructions for using R and R-Commander are provided. Topics include data exploration, estimation, hypothesis testing, linear regression analysis, and clustering with two appendices on installing and using R and R-Commander. A novel feature of this book is an introduction to Bayesian analysis. This author discusses basic statistical analysis through a series of biological examples using R and R-Commander as computational tools. The book is ideal for instructors of basic statistics for biologists and other health scientists. The step-by-step application of statistical methods discussed in this book allows readers, who are interested in statistics and its application in biology, to use the book as a self-learning text.

Foundational and Applied Statistics for Biologists Using R

Foundational and Applied Statistics for Biologists Using R PDF

Author: Ken A. Aho

Publisher: CRC Press

Published: 2016-03-09

Total Pages: 598

ISBN-13: 1439873399

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Full of biological applications, exercises, and interactive graphical examples, Foundational and Applied Statistics for Biologists Using R presents comprehensive coverage of both modern analytical methods and statistical foundations. The author harnesses the inherent properties of the R environment to enable students to examine the code of complica

Using R for Biostatistics

Using R for Biostatistics PDF

Author: Thomas W. MacFarland

Publisher: Springer Nature

Published: 2021-03-02

Total Pages: 929

ISBN-13: 3030624048

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This book introduces the open source R software language that can be implemented in biostatistics for data organization, statistical analysis, and graphical presentation. In the years since the authors’ 2014 work Introduction to Data Analysis and Graphical Presentation in Biostatistics with R, the R user community has grown exponentially and the R language has increased in maturity and functionality. This updated volume expands upon skill-sets useful for students and practitioners in the biological sciences by describing how to work with data in an efficient manner, how to engage in meaningful statistical analyses from multiple perspectives, and how to generate high-quality graphics for professional publication of their research. A common theme for research in the diverse biological sciences is that decision-making depends on the empirical use of data. Beginning with a focus on data from a parametric perspective, the authors address topics such as Student t-Tests for independent samples and matched pairs; oneway and twoway analyses of variance; and correlation and linear regression. The authors also demonstrate the importance of a nonparametric perspective for quality assurance through chapters on the Mann-Whitney U Test, Wilcoxon Matched-Pairs Signed-Ranks test, Kruskal-Wallis H-Test for Oneway Analysis of Variance, and the Friedman Twoway Analysis of Variance. To address the element of data presentation, the book also provides an extensive review of the many graphical functions available with R. There are now perhaps more than 15,000 external packages available to the R community. The authors place special emphasis on graphics using the lattice package and the ggplot2 package, as well as less common, but equally useful, figures such as bean plots, strip charts, and violin plots. A robust package of supplementary material, as well as an introduction of the development of both R and the discipline of biostatistics, makes this ideal for novice learners as well as more experienced practitioners.

Biostatistics with R

Biostatistics with R PDF

Author: Jan Lepš

Publisher: Cambridge University Press

Published: 2020-07-30

Total Pages: 385

ISBN-13: 1108480381

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A straightforward introduction to a wide range of statistical methods for field biologists, using thoroughly explained R code.

Applied Meta-Analysis with R

Applied Meta-Analysis with R PDF

Author: Ding-Geng (Din) Chen

Publisher: CRC Press

Published: 2013-05-03

Total Pages: 338

ISBN-13: 1466505990

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In biostatistical research and courses, practitioners and students often lack a thorough understanding of how to apply statistical methods to synthesize biomedical and clinical trial data. Filling this knowledge gap, Applied Meta-Analysis with R shows how to implement statistical meta-analysis methods to real data using R. Drawing on their extensive research and teaching experiences, the authors provide detailed, step-by-step explanations of the implementation of meta-analysis methods using R. Each chapter gives examples of real studies compiled from the literature. After presenting the data and necessary background for understanding the applications, various methods for analyzing meta-data are introduced. The authors then develop analysis code using the appropriate R packages and functions. This systematic approach helps readers thoroughly understand the analysis methods and R implementation, enabling them to use R and the methods to analyze their own meta-data. Suitable as a graduate-level text for a meta-data analysis course, the book is also a valuable reference for practitioners and biostatisticians (even those with little or no experience in using R) in public health, medical research, governmental agencies, and the pharmaceutical industry.

The R Book

The R Book PDF

Author: Michael J. Crawley

Publisher: John Wiley & Sons

Published: 2007-06-13

Total Pages: 953

ISBN-13: 9780470515068

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The high-level language of R is recognized as one of the mostpowerful and flexible statistical software environments, and israpidly becoming the standard setting for quantitative analysis,statistics and graphics. R provides free access to unrivalledcoverage and cutting-edge applications, enabling the user to applynumerous statistical methods ranging from simple regression to timeseries or multivariate analysis. Building on the success of the author’s bestsellingStatistics: An Introduction using R, The R Book ispacked with worked examples, providing an all inclusive guide to R,ideal for novice and more accomplished users alike. The bookassumes no background in statistics or computing and introduces theadvantages of the R environment, detailing its applications in awide range of disciplines. Provides the first comprehensive reference manual for the Rlanguage, including practical guidance and full coverage of thegraphics facilities. Introduces all the statistical models covered by R, beginningwith simple classical tests such as chi-square and t-test. Proceeds to examine more advance methods, from regression andanalysis of variance, through to generalized linear models,generalized mixed models, time series, spatial statistics,multivariate statistics and much more. The R Book is aimed at undergraduates, postgraduates andprofessionals in science, engineering and medicine. It is alsoideal for students and professionals in statistics, economics,geography and the social sciences.

Clinical Trial Data Analysis Using R and SAS

Clinical Trial Data Analysis Using R and SAS PDF

Author: Ding-Geng (Din) Chen

Publisher: CRC Press

Published: 2017-06-01

Total Pages: 310

ISBN-13: 1351651145

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Review of the First Edition "The goal of this book, as stated by the authors, is to fill the knowledge gap that exists between developed statistical methods and the applications of these methods. Overall, this book achieves the goal successfully and does a nice job. I would highly recommend it ...The example-based approach is easy to follow and makes the book a very helpful desktop reference for many biostatistics methods."—Journal of Statistical Software Clinical Trial Data Analysis Using R and SAS, Second Edition provides a thorough presentation of biostatistical analyses of clinical trial data with step-by-step implementations using R and SAS. The book’s practical, detailed approach draws on the authors’ 30 years’ experience in biostatistical research and clinical development. The authors develop step-by-step analysis code using appropriate R packages and functions and SAS PROCS, which enables readers to gain an understanding of the analysis methods and R and SAS implementation so that they can use these two popular software packages to analyze their own clinical trial data. What’s New in the Second Edition Adds SAS programs along with the R programs for clinical trial data analysis. Updates all the statistical analysis with updated R packages. Includes correlated data analysis with multivariate analysis of variance. Applies R and SAS to clinical trial data from hypertension, duodenal ulcer, beta blockers, familial andenomatous polyposis, and breast cancer trials. Covers the biostatistical aspects of various clinical trials, including treatment comparisons, time-to-event endpoints, longitudinal clinical trials, and bioequivalence trials.

Biostatistical Analysis

Biostatistical Analysis PDF

Author: Jerrold H. Zar

Publisher:

Published: 2014

Total Pages: 756

ISBN-13: 9781292024042

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Zar's Biostatistncal Analysis, Fifth Edition, is the ideal textbook for graduate and undergraduate students seeking practncal coverage of statistncal analysis methods used by researchers to collect, summarize, analyze and draw conclusnons from biologic E research. The latest editnon of this best-selling textbook is both comprehensive and easy to read. It is suitable as an introductnon for begnnnnng students and as a comprehensive reference book for biologic E researchers and for advanced students. This book is appropriate for a one- or two-semester, junior or graduate-level course in biostatistncs, biometry, quantitatnve biology, or statistics, and assumes a prerequisite ofalgebra.

Biostatistics for Epidemiology and Public Health Using R

Biostatistics for Epidemiology and Public Health Using R PDF

Author: Bertram K.C. Chan, PhD

Publisher: Springer Publishing Company

Published: 2015-11-05

Total Pages: 500

ISBN-13: 0826110266

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Since it first appeared in 1996, the open-source programming language R has become increasingly popular as an environment for statistical analysis and graphical output. This is the first textbook to present classical biostatistical analysis for epidemiology and related public health sciences to students using the R language. Based on the assumption that readers have minimal familiarity with statistical concepts, the author uses a step-by-step approach to building skills. The text encompasses biostatistics from basic descriptive and quantitative statistics to survival analysis and missing data analysis in epidemiology. Illustrative examples, including real-life research problems drawn from such areas as nutrition, environmental health, and behavioral health, engage students and reinforce the understanding of R. These examples illustrate the replication of R for biostatistical calculations and graphical display of results. The text covers both essential and advanced techniques and applications in biostatistics that are relevant to epidemiology. Also included are an instructor's guide, student solutions manual, and downloadable data sets. Key Features: First overview biostatistics textbook for epidemiology and public health that uses the open-source R program Covers essential and advanced techniques and applications in biostatistics as relevant to epidemiology Features abundant examples to illustrate the application of R language for biostatistical calculations and graphical displays of results Includes instructor's guide, student solutions manual, and downloadable data sets.