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Biosensing

Author: Jerome Schultz

Publisher: Springer Science & Business Media

Published: 2006-07-15

Total Pages: 409

ISBN-13: 140204058X

We have come to know that our ability to survive and grow as a nation to a very large degree depends upon our scientific progress. Moreover, it is not enough simply to keep abreast of the rest of the world in scientific matters. 1 We must maintain our leadership. President Harry Truman spoke those words in 1950, in the aftermath of World War II and in the midst of the Cold War. Indeed, the scientific and engineering leadership of the United States and its allies in the twentieth century played key roles in the successful outcomes of both World War II and the Cold War, sparing the world the twin horrors of fascism and totalitarian communism, and fueling the economic prosperity that followed. Today, as the United States and its allies once again find themselves at war, President Truman’s words ring as true as they did a half-century ago. The goal set out in the Truman Administration of maintaining leadership in science has remained the policy of the U.S. Government to this day: Dr. John Marburger, the Director of the Office of Science and Technology (OSTP) in the Executive Office of the President made remarks to that effect during his confirmation hearings in October 2 2001.

Biosensing Using Nanomaterials

Author: Arben Merkoci

Publisher: John Wiley & Sons

Published: 2009-03-25

Total Pages: 523

ISBN-13: 0470447729

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An interdisciplinary approach to one of the hottest topics in nanotechnology and nanoscience Biosensing Using Nanomaterials introduces novel concepts in the area of bioanalysis based on nanomaterials, opening new opportunities for basic research and new tools for real bioanalytical applications. In fifteen chapters, readers are introduced to the most successful nanomaterials used so far in biosensing, including carbon nanotubes, nanoparticles, and nanochannels. Each chapter provides a theoretical overview of the topic, a discussion of the published data relating to the bioanalytical system, and a selected list of references for further investigation. The result is a book that provides a comprehensive forum of interest to scientists, engineers, researchers, manufacturers, teachers, and students. Biosensing Using Nanomaterials is an important resource for a broad audience involved in the research, teaching, learning, and practice of integrating nanomaterials into biosensing systems for clinical, environmental, and industrial applications.

Optical Whispering Gallery Modes for Biosensing

Author: Frank Vollmer

Publisher: Springer Nature

Published: 2020-10-16

Total Pages: 424

ISBN-13: 3030602354

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This interdisciplinary book covers the fundamentals of optical whispering gallery mode (WGM) microcavities, light–matter interaction, and biomolecular structure with a focus on applications in biosensing. Novel biosensors based on the hybridization of WGM microcavities and localized surface plasmon resonances (LSPRs) in metal nanoparticles have emerged as the most sensitive microsystem biodetection technology that boasts single molecule detection capability without the need for amplification and labeling of the analyte. The book provides an ample survey of the physical mechanisms of WGMs and LSPRs for detecting affinity, concentration, size, shape and orientation of biomarkers, while informing the reader about different classes of biomolecules, their optical properties and their importance in label-free clinical diagnostics. For the more advanced reader, advanced applications of WGMs and LSPRs in exploring the fundamental nature of quantum physics are discussed.

Wearable Biosensing in Medicine and Healthcare

Author: Kohji Mitsubayashi

Publisher: Springer Nature

Published: 2024-01-03

Total Pages: 483

ISBN-13: 9819981220

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This book contains chapters on wearable biomedical sensors and their assistive technologies for promoting behavioral change in medical and health care. Part I reviews several wearable biomedical sensors based on biocompatible materials and nano and micro-electromechanical systems (MEMS) technologies in the medical and dental fields. Part II introduces the latest approaches to wearable biosensing using unique devices for various skin targets such as sweat, interstitial fluid, and transcutaneous gases. Part III presents technologies supporting wearable sensors, including soft and flexible materials, manufacturing methods, skin volatile-marker imaging, and energy harvesting devices. This book is intended for graduate students, academic researchers, and professors that work in medical and healthcare research fields, as well as industry professionals involved in the development of wearable and flexible sensing devices and measurement systems for human bio/chemical sensing, medical monitoring, and healthcare services, and for medical professionals and government officials who are driving behavior change in health care.

Biophotonics and Biosensing

Author: Andrea Armani

Publisher: Elsevier

Published: 2024-06-03

Total Pages: 520

ISBN-13: 0443188416

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Biophotonics and Biosensing: From Fundamental Research to Clinical Trials Through Advances of Signal and Image Processing brings together the knowledge of the basic principles of the field of light-biological tissue interaction, detection methods, data processing techniques, and research, diagnostic and clinical applications. It is suitable for new entrants, while also highlighting the latest developments for experts in the field. This volume includes perspectives by leading experts from the biophotonics, biomedical engineering, and data science communities. The reader will receive a basic grounding in the key theoretical principles and practical components of biophotonics and biosensing. Working principles of devices used in spectroscopy, microscopy, and optical sensing are presented along with their application domains. The reader will learn about existing microscopy-based techniques used in biomedical applications for diagnosis and get to know different signal processing algorithms as used in biophotonics. Finally, through concrete examples, including sample preparation and measurement approaches, see how the field has developed thanks to the integration of biophotonics and optical biosensing with signal processing. Introduces key principles of light-biological tissue interactions and biosensing Discusses how the most promising optical diagnostic methods can exploit contemporary signal and image processing algorithms and data analytics Includes examples of clinical studies with detailed descriptions of their implementation, along with practical guidance

Functionalized Nanomaterials for Biosensing and Bioelectronics Applications

Author: Sudheesh K. Shukla

Publisher: Woodhead Publishing

Published: 2024-06-28

Total Pages: 378

ISBN-13: 0128238437

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Functionalized Nanomaterials for Biosensing and Bioelectronics Applications: Trends and Challenges describes current and future opportunities for integrating the unique properties of two-dimensional nanomaterials with bioelectronic interfaces. Sections focus on background information and fundamental concepts, review the available functionalized nanomaterials and their properties, explore the integration of functionalized nanomaterials with bioelectronics, including available fabrication and characterization methods, electrical behavior at the interface, and design and synthesis guidelines, and review examples of microsystems where functionalized nanomaterials are being integrated with bioelectronics. This book is suitable for researchers and practitioners in academia and R&D working in materials science and engineering, analytical chemistry and related fields. Introduces the most common functionalized nanomaterials and their morphologies, properties, and mechanisms for sensing applications Reviews functionalization and fabrication methods and techniques for the integration of one- and two-dimensional materials for sensing applications Addresses the most relevant applications of functionalized nanomaterials for biosensing and bioelectronics applications

Sensing and Biosensing with Optically Active Nanomaterials

Author: Suban K. Sahoo

Publisher: Elsevier

Published: 2021-10-21

Total Pages: 596

ISBN-13: 0323902456

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Sensing and Biosensing with Optically Active Nanomaterials summarizes the potential sensing applications of optically (chromogenic and fluorogenic) active, nano-sized, organic, and inorganic materials for the selective detection of ionic analytes (such as metal ions and anions) in various environmental and biological samples. Sections cover design, synthesis, sensing mechanisms and applications for detecting ionic analytes. Each chapter deals with the sensing applications of one kind of nanomaterial. This book is an important reference source for materials scientists and engineers seeking to increase their understanding on how nanomaterials are being used for sensing applications. Provides information on the various types of optically active inorganic and organic nanomaterials, including quantum dots, SPR active noble metal nanoparticles, metal nanoclusters, organic nanoparticles and carbon dots Summarizes the synthesis, design and development of sensors, along with their mechanisms Explains major sensing applications and manufacturing challenges

Biosensing Technologies for the Detection of Pathogens

Author: Toonika Rinken

Publisher: BoD – Books on Demand

Published: 2018-03-21

Total Pages: 218

ISBN-13: 9535139150

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Rapid multiplex detection of pathogens in the environment and in our food is a key factor for the prevention and effective treatment of infectious diseases. Biosensing technologies combining the high selectivity of biomolecular recognition and the sensitivity of modern signal detection platforms are a prospective option for automated analyses. They allow rapid detection of single molecules as well as cellular substances. This book, including 12 chapters from 50 authors, introduces the principles of identification of specific pathogen biomarkers along with different biosensor-based technologies applied for pathogen detection.

Advances in Biosensing Technology for Medical Diagnosis

Author: Han-Sheng Chuang

Publisher: Bentham Science Publishers

Published: 2020-10-14

Total Pages: 530

ISBN-13: 9811464766

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Biosensing technology is rapidly flourishing in recent years due to the advancement of bio-MEMS/NEMS. However, the booming development of biosensors has not been very well addressed to the unmet clinical needs. Advances in Biosensing Technology for Medical Diagnosis initiates a headway into the realm of cutting-edge diagnostic tools which are expected to become routine clinical practice. This book aims to broaden the readers’ horizon and guide them in tailoring different biosensing techniques for specific diagnostic procedures. Key Features: - 12 chapters cover several aspects of biosensing technologies including working principles and clinical validations - highlights the state-of-the-art biosensing technology developed in all fields - provides information about specific applications of novel biosensors used in clinical diagnosis, - provides step-by-step guidance of microfabrication for biosensors - focuses on bridging the gap between the scientific and the clinical communities - provides information about the diagnostic applications of biosensors for different diseases (including infectious diseases and neurodegenerative diseases). - covers Information about unconventional nano/microfluidic biosensor systems - features contributions from renowned experts in the field of biomedical engineering Advances in Biosensing Technology for Medical Diagnosis serves as a reference for healthcare providers and biomedical engineers who are interesting in biosensing techniques in medicine. The information provided in this reference will also benefit healthcare policymakers who are interested in new technologies that can impact the delivery of diagnostic services in healthcare systems.

Optical and Electrochemical Biosensing

Author: Junjie Zhu

Publisher: Frontiers Media SA

Published: 2022-09-27

Total Pages: 90

ISBN-13: 2832500943

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The transduction of unreadable chemical/biological components to readable optical or electrochemical signals utilizing different biosensing technologies is one of the important pathways of understanding the principles of nature. To achieve this ambitious goal, many biosensors have been developed to obtain useful information from complex systems (e.g. cells, tissues, and humans) ever since the first glucose biosensor was invented in 1967. Nowadays, biosensors are spread all over every branch of frontier science ranging from fundamental measurement science to advanced artificial intelligence technology. Although many transduction technologies are available so far, optical and electronic signals are still two of the most commonly used techniques as the detectable outputs for biosensors. Taking advantage of the development of additive manufacturing techniques such as 3D printing and the improved understanding of the biomolecules, optical and electrochemical biosensing technologies have also been developed on their sensitivity, selectivity and speed. In view of the fast development in the area, we propose a Research Topic focused on the recent development of optical and electrochemical biosensing. The topics of the Research Topic cover various optical and electrochemical biosensors, which potentially promote the revolution of modern measurement techniques. Notably, this issue will not only cover the topics in individually used optical or electrochemical biosensors but also receive interconnection techniques between optical and electrochemical signals. We welcome submissions in the following themes, but not limited to: • Fundamental studies of the optical and electrochemical biosensing • Optical biosensing techniques • Electrochemical biosensing techniques • Combined optical and electrochemical biosensors • Commercializing of the optical and electrochemical biosensors • In vivo and in vitro optical and electrochemical biosensing