Biosafety First

Biosafety First PDF

Author: Terje Traavik

Publisher: Fagbokforlaget

Published: 2007

Total Pages: 616

ISBN-13:

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The challenges for risk identification, assessment and management posed by genetic engineering and genetically modified organisms are some of the most demanding issues facing many countries and societies today. The evolving field of biosafety has developed in response to these challenges. BIOSAFETY FIRST is a stimulating collection of the latest thinking concerning biosafety science. It is a unique work as its approach to biosafety is holistic, encompassing not only the scientific, but also the socio-economic, cultural, policy and regulatory spheres. It does not claim to give all the answers, but acknowledges the issues and points to the uncertainties and knowledge gaps that still need to be addressed. Drawing on the new scientific field of gene ecology, and advocating a precautionary approach, this book provides a foundation on which countries can start to openly and responsibly appraise these new technologies and their products.

Biological Safety

Biological Safety PDF

Author: Dawn P. Wooley

Publisher: John Wiley & Sons

Published: 2017-02-01

Total Pages: 953

ISBN-13: 1683673131

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Biological safety and biosecurity protocols are essential to the reputation and responsibility of every scientific institution, whether research, academic, or production. Every risk—no matter how small—must be considered, assessed, and properly mitigated. If the science isn't safe, it isn't good. Now in its fifth edition, Biological safety: Principles and Practices remains the most comprehensive biosafety reference. Led by editors Karen Byers and Dawn Wooley, a team of expert contributors have outlined the technical nuts and bolts of biosafety and biosecurity within these pages. This book presents the guiding principles of laboratory safety, including: the identification, assessment, and control of the broad variety of risks encountered in the lab; the production facility; and, the classroom. Specifically, Biological Safety covers protection and control elements—from biosafety level cabinets and personal protection systems to strategies and decontamination methods administrative concerns in biorisk management, including regulations, guidelines, and compliance various aspects of risk assessment covering bacterial pathogens, viral agents, mycotic agents, protozoa and helminths, gene transfer vectors, zooonotic agents, allergens, toxins, and molecular agents as well as decontamination, aerobiology, occupational medicine, and training A resource for biosafety professionals, instructors, and those who work with pathogenic agents in any capacity, Biological safety is also a critical reference for laboratory managers, and those responsible for managing biohazards in a range of settings, including basic and agricultural research, clinical laboratories, the vivarium, field study, insectories, and greenhouses.

Laboratory Biorisk Management

Laboratory Biorisk Management PDF

Author: Reynolds M. Salerno

Publisher: CRC Press

Published: 2015-12-01

Total Pages: 198

ISBN-13: 1498749747

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Over the past two decades bioscience facilities worldwide have experienced multiple safety and security incidents, including many notable incidents at so-called "sophisticated facilities" in North America and Western Europe. This demonstrates that a system based solely on biosafety levels and security regulations may not be sufficient. Setting the stage for a substantively different approach for managing the risks of working with biological agents in laboratories, Laboratory Biorisk Management: Biosafety and Biosecurity introduces the concept of biorisk management—a new paradigm that encompasses both laboratory biosafety and biosecurity. The book also provides laboratory managers and directors with the information and technical tools needed for its implementation. The basis for this new paradigm is a three-pronged, multi-disciplinary model of assessment, mitigation, and performance (the AMP model). The application of the methodologies, criteria, and guidance outlined in the book helps to reduce the risk of laboratories becoming the sources of infectious disease outbreaks. This is a valuable resource for those seeking to embrace and implement biorisk management systems in their facilities and operations, including the biological research, clinical diagnostic, and production/manufacturing communities.

Laboratory Biosafety Manual

Laboratory Biosafety Manual PDF

Author: World Health Organization

Publisher: World Health Organization

Published: 2004-12-28

Total Pages: 196

ISBN-13: 9789241546508

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This is the third edition of this manual which contains updated practical guidance on biosafety techniques in laboratories at all levels. It is organised into nine sections and issues covered include: microbiological risk assessment; lab design and facilities; biosecurity concepts; safety equipment; contingency planning; disinfection and sterilisation; the transport of infectious substances; biosafety and the safe use of recombinant DNA technology; chemical, fire and electrical safety aspects; safety organisation and training programmes; and the safety checklist.

Working in Biosafety Level 3 and 4 Laboratories

Working in Biosafety Level 3 and 4 Laboratories PDF

Author: Manfred Weidmann

Publisher: John Wiley & Sons

Published: 2013-12-04

Total Pages: 0

ISBN-13: 9783527334674

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The first training manual for new staff working in BSL3/4 labs. This guide is based on a course developed in 2007 by the EU COST action group 28b which serves as a standard for many courses BSL3/4 training courses worldwide. The four-day course consists of lectures and practical training with the lecturers covering all the different possibilities of organising a BSL-3/4 lab including the adaptation to the local requirements of biosafety, safety at work, and social regulations. This book covers bio-containment, hazard criteria and categorisation of microbes, technical specifications of BSL-3 laboratories and ABSL-3 laboratories, personal protective gear, shipping BSL-3 and BSL-4 organisms according to UN and IATA regulations, efficacy of inactivation procedures, fumigation, learning from a history of lab accidents, handling samples that arrive for diagnostic testing and bridging the gap between the requirements of bio-containment and diagnostics. Course participants can not only use the book for their actual training event but it will remain a useful reference throughout their career in BSL3/4 labs.

How to Be a Laboratory Biosafety Officer First Edition

How to Be a Laboratory Biosafety Officer First Edition PDF

Author: Philip Dauterman

Publisher: Createspace Independent Publishing Platform

Published: 2018-01-30

Total Pages: 102

ISBN-13: 9781983589157

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How to be a Laboratory Biosafety Officer. The Lab Biosafety Officer position is responsible for ensuring laboratory safety and security against all hazards including biological, chemical and physical hazards. This includes containment of infectious organisms, knowledge of Biosafety Containment Levels (BSL), proper use of Personal Protective Equipment (PPE), Biosafety Cabinets (BSC), isolation precautions and infection control, knowledge of disinfection, high level disinfection, sterilization, autoclaves and proper disposal of lab waste. This position is also responsible for chemical hazard containment and decontamination including knowledge of fire cabinets, corrosive cabinets, emergency eyewashes and emergency showers. The Lab BSO is also responsible for hazardous materials (dangerous goods) shipping, responding to spills and accidents, making risk assessments, writing procedures, writing the Biosafety Manual and making reports. The lab Biosafety Officer is responsible for disaster planning, preparedness and responding to spills, accidents and incidents.

Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories

Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories PDF

Author: National Research Council

Publisher: National Academies Press

Published: 2012-04-02

Total Pages: 216

ISBN-13: 0309225752

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During July 10-13, 2011, 68 participants from 32 countries gathered in Istanbul, Turkey for a workshop organized by the United States National Research Council on Anticipating Biosecurity Challenges of the Global Expansion of High-containment Biological Laboratories. The United States Department of State's Biosecurity Engagement Program sponsored the workshop, which was held in partnership with the Turkish Academy of Sciences. The international workshop examined biosafety and biosecurity issues related to the design, construction, maintenance, and operation of high-containment biological laboratories- equivalent to United States Centers for Disease Control and Prevention biological safety level 3 or 4 labs. Although these laboratories are needed to characterize highly dangerous human and animal pathogens, assist in disease surveillance, and produce vaccines, they are complex systems with inherent risks. Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories summarizes the workshop discussion, which included the following topics: Technological options to meet diagnostic, research, and other goals; Laboratory construction and commissioning; Operational maintenance to provide sustainable capabilities, safety, and security; and Measures for encouraging a culture of responsible conduct. Workshop attendees described the history and current challenges they face in their individual laboratories. Speakers recounted steps they were taking to improve safety and security, from running training programs to implementing a variety of personnel reliability measures. Many also spoke about physical security, access controls, and monitoring pathogen inventories. Workshop participants also identified tensions in the field and suggested possible areas for action.

Biosafety in Microbiological and Biomedical Laboratories

Biosafety in Microbiological and Biomedical Laboratories PDF

Author: L. Casey Chosewood

Publisher: DIANE Publishing

Published: 2007-08

Total Pages: 426

ISBN-13: 9781422315361

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¿Biosafety in Microbiological & Biomedical Labs.¿ quickly became the cornerstone of biosafety practice & policy upon first pub. in 1984. The info. is advisory in nature even though legislation & reg¿n., in some circumstances, have overtaken it & made compliance with the guidance mandatory. This rev. contains these add¿l. chap.: Occupat¿l. med. & immunization; Decontam. & sterilization; Lab. biosecurity & risk assess.; Biosafety Level 3 (Ag.) labs.; Agent summary state. for some ag. pathogens; & Biological toxins. Also, chapters on the principles & practices of biosafety & on risk assess. were expanded; all agent summary state. & append. were rev.; & efforts were made to harmonize recommend. with reg¿s. promulgated by other fed. agencies.