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Biopolymers in Drug Delivery and Regenerative Medicine

Author: Carlos A Garcia-Gonzalez

Publisher: Mdpi AG

Published: 2021-06-16

Total Pages: 194

ISBN-13: 9783036509006

Biopolymers including natural (e.g., polysaccharides, proteins, gums, natural rubbers, bacterial polymers), synthetic (e.g., aliphatic polyesters and polyphosphoester), and biocomposites are of paramount interest in regenerative medicine, due to their availability, processability, and low toxicity. Moreover, the structuration of biopolymer-based materials at the nano- and microscale along with their chemical properties are crucial in the engineering of advanced carriers for drug products. Finally, combination products including or based on biopolymers for controlled drug release offer a powerful solution to improve the tissue integration and biological response of these materials. Understanding the drug delivery mechanisms, efficiency, and toxicity of such systems may be useful for regenerative medicine and pharmaceutical technology.

Natural Biopolymers in Drug Delivery and Tissue Engineering

Author: Rangasamy Jayakumar

Publisher: Elsevier

Published: 2023-08-24

Total Pages: 709

ISBN-13: 032398648X

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Natural Biopolymers in Drug Delivery and Tissue Engineering systematically examines a broad range of natural polymers and their applications in drug delivery and tissue engineering. The book thoroughly collates the most relevant and up-to-date research on natural biopolymers, covering a variety of key natural polymer types such as chitin, chitosan, alginate, guar gum and collagen. It is divided into two sections, covering drug delivery and tissue engineering applications. Each section focuses on natural biopolymers in the form of scaffolds, membranes, films, gels and nanoparticles, thus helping the reader select not only the most appropriate polymer type, but also the most relevant structure. This comprehensive resource is ideal for materials scientists, biomedical engineers, tissue engineers, pharmaceutical scientists and anyone interested in developing novel materials for biomedical applications. Covers both drug delivery and tissue engineering applications of natural biopolymers, helping bridge the gap between the two Details a range of natural polymer types, ensuring all relevant options are presented Discusses the benefits, challenges and clinical translation of natural biopolymers

Biopolymers for Medical Applications

Author: Juan M. Ruso

Publisher: CRC Press

Published: 2017-02-17

Total Pages: 373

ISBN-13: 1498744974

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This book presents an experimental and computational account of the applications of biopolymers in the field of medicine. Biopolymers are macromolecules produced by living systems, such as proteins, polypeptides, nucleic acids, and polysaccharides. Their advantages over polymers produced using synthetic chemistry include: diversity, abundance, relatively low cost, and sustainability. This book explains techniques for the production of different biodevices, such as scaffolds, hydrogels, functional nanoparticles, microcapsules, and nanocapsules. Furthermore, developments in nanodrug delivery, gene therapy, and tissue engineering are described.

Biopolymers In Drug Delivery: Recent Advances and Challenges

Author: Michael U. Adikwu

Publisher: Bentham Science Publishers

Published: 2010-05-13

Total Pages: 232

ISBN-13: 1608050785

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"This Ebook describes the applicability of diverse natural and synthetic biopolymers and their blends in drugs, vaccines and gene delivery. It would serve as a concise body of information on biopolymers for researchers, industries and students of pharmaceu"

Biopolymers for Biomedical and Biotechnological Applications

Author: Bernd H. A. Rehm

Publisher: John Wiley & Sons

Published: 2021-07-06

Total Pages: 400

ISBN-13: 3527345302

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Provides insight into biopolymers, their physicochemical properties, and their biomedical and biotechnological applications This comprehensive book is a one-stop reference for the production, modifications, and assessment of biopolymers. It highlights the technical and methodological advancements in introducing biopolymers, their study, and promoted applications. "Biopolymers for Biomedical and Biotechnological Applications" begins with a general overview of biopolymers, properties, and biocompatibility. It then provides in-depth information in three dedicated sections: Biopolymers through Bioengineering and Biotechnology Venues; Polymeric Biomaterials with Wide Applications; and Biopolymers for Specific Applications. Chapters cover: advances in biocompatibility; advanced microbial polysaccharides; microbial cell factories for biomanufacturing of polysaccharides; exploitation of exopolysaccharides from lactic acid bacteria; and the new biopolymer for biomedical application called nanocellulose. Advances in mucin biopolymer research are presented, along with those in the synthesis of fibrous proteins and their applications. The book looks at microbial polyhydroxyalkanoates (PHAs), as well as natural and synthetic biopolymers in drug delivery and tissue engineering. It finishes with a chapter on the current state and applications of, and future trends in, biopolymers in regenerative medicine. * Offers a complete and thorough treatment of biopolymers from synthesis strategies and physiochemical properties to applications in industrial and medical biotechnology * Discusses the most attracted biopolymers with wide and specific applications * Takes a systematic approach to the field which allows readers to grasp and implement strategies for biomedical and biotechnological applications "Biopolymers for Biomedical and Biotechnological Applications" appeals to biotechnologists, bioengineers, and polymer chemists, as well as to those working in the biotechnological industry and institutes.

Hydrogels

Author: Thakur Raghu Raj Singh

Publisher: CRC Press

Published: 2018-02-28

Total Pages: 309

ISBN-13: 1351648276

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Hydrogels are crosslinked, macromolecular polymeric materials arranged in a three-dimensional network, which can absorb and retain large amounts of water. Hydrogels are commonly used in clinical practice and experimental medicine for a wide range of applications, including drug delivery, tissue engineering and regenerative medicine, diagnostics, cellular immobilization, separation of biomolecules or cells, and barrier materials to regulate biological adhesions. This book elucidates the underlying concepts and emerging applications of hydrogels and will provide key case studies and critical analysis of the existing research.

Biopolymer-Based Composites

Author: Sougata Jana

Publisher: Woodhead Publishing

Published: 2017-06-15

Total Pages: 422

ISBN-13: 0081019157

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Biopolymer-Based Composites: Drug Delivery and Biomedical Applications presents a comprehensive review on recent developments in biopolymer-based composites and their use in drug delivery and biomedical applications. The information contained in this book is critical for the more efficient use of composites, as detailed up-to-date information is a pre-requirement. The information provided brings cutting-edge developments to the attention of young investigators to encourage further advances in the field of bio-composite research. Currently, biopolymers are being investigated for the design of various drug delivery and biomedical devices due to their non-toxic, biodegradable and biocompatible nature. Mostly, biopolymer-based solid orals, gels, hydrogel beads, and transdermal matrices have been designed in order to control drug/protein release in simulated bio-fluids. Presents the most updated information in the field of pharmaceutical and biological sciences Contains color figures and illustrations to help users understand key topics Useful guide for young researchers working towards new innovations Includes chapters covered by eminent scientists in the field

Plant and Algal Hydrogels for Drug Delivery and Regenerative Medicine

Author: Tapan Kumar Giri

Publisher: Woodhead Publishing

Published: 2021-06-12

Total Pages: 592

ISBN-13: 0128216506

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Plant and Algal Hydrogels for Drug Delivery and Regenerative Medicine offers a materials-focused and systematic overview of biopolymeric hydrogels utilized for biomedical applications. The book details the synthesis and characterization of plant and algal-based hydrogels, with each chapter addressing a separate polysaccharide hydrogel type. Specific applications in drug delivery and regenerative medicine are also discussed, highlighting the efficacy, biocompatibility, benefits and challenges for each polysaccharide hydrogel subtype. There is increasing demand for biomaterials which reduce/prevent the host response, inflammation and rejection, hence this book provides a timely resource. Biopolymeric hydrogels have skyrocketed because of their necessity in in vivo applications. They create an environment similar to living tissue, which is both biocompatible and biodegradable. Plant and algal polysaccharides in particular are well-equipped with functional groups that are easily modified for beneficial results. Systematically covers each plant and algal polysaccharide hydrogel subtype, from starch-based hydrogels to pectin and alginate-based hydrogels Provides an end-to-end description of the synthesis, characterization and application of biopolymeric hydrogels for drug delivery and regenerative medicine Appeals to a diverse readership, including those in biomedicine, pharmacy, polymer chemistry, biochemistry, materials science, biomedical engineering, and other biotechnology related disciplines

Cationic Polymers in Regenerative Medicine

Author: Sangram Keshari Samal

Publisher: Royal Society of Chemistry

Published: 2014-11-14

Total Pages: 612

ISBN-13: 1782620109

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The unique physico-chemical properties of cationic polymers and their ability to be easily modified make them attractive for many biological applications. As a result there is a vast amount of research focussed on designing novel natural or synthetic cationic polymers with specific biological functionality. Cationic Polymers in Regenerative Medicine brings together the expertise of leading experts in the field to provide a comprehensive overview of the recent advances in cationic polymer synthesis, modification and the design of biomaterials with different structures for therapeutic applications. Chapters cover recent developments in novel cationic polymer based systems including poly(L-lysine), Poly(N,N-dimethylaminoethyl methacrylate) and cationic triazine dendrimers as well as cationic polymer-coated micro- and nanoparticles and cationic cellulose and chitin nanocrystals. Applications discussed in the book include drug and gene delivery, therapeutics in thrombosis and inflammation as well as gene therapy. Suitable both for an educational perspective for those new to the field and those already active in the field, the book appeals to postgraduates and researchers. The broad aspects of the topics covered are suitable for polymer chemists interested in the fundamentals of the materials systems as well as pharmaceutical chemists, bioengineering and medical professionals interested in their applications.

Recent Advances in Biopolymers

Author: Farzana Khan Perveen

Publisher: BoD – Books on Demand

Published: 2016-03-09

Total Pages: 290

ISBN-13: 953512255X

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This book contains 10 Chapters divided into three Sections. Section A covers synthesis of biopolymers. Lignocellulosic feedstock contains cellulose, hemicellulose, and lignin, which are used for synthesis of biopolymers. Polymer-coated noble metal nanoparticles are used in nanobiomedicine and fundamental biomaterials. Section B describes applications of biopolymers in biomedical, antimicrobial, industrial, nanotechnology, laser-based thin films, and regenerative medicines. Section C is dedicated for advancement and engineering in biopolymers for personal protective garments, equipments, membrane separation processes, purifications, and new generation of high-performance biomaterials. A new numerical-cum-graphical method called TI2BioP (Topological Indices to BioPolymers) has been developed to estimate topological indices (TIs) from two-dimensional (2D) graphical approaches for the natural biopolymers DNA, RNA, and proteins.