Biomembranes

Biomembranes PDF

Author: Robert B. Gennis

Publisher: Springer Science & Business Media

Published: 2013-04-17

Total Pages: 549

ISBN-13: 1475720653

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New textbooks at all levels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical thermody namics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the graduate level, suffer from a real lack of up-to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research which is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive introductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In some cases, the availability of texts in active research areas should help stimulate the creation of new courses.

Lipid Peroxidation In Biomembranes

Lipid Peroxidation In Biomembranes PDF

Author: Valerian E. Kagan

Publisher: CRC Press

Published: 2018-01-18

Total Pages: 189

ISBN-13: 1351090984

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This book will explain the colossal potential of life to cope with different living environments is possible owing to the exceptionally well developed mechanisms of adaptation to environmental conditions. There is an innumerable variety of concrete mechanisms which make it possible for living creatures to adapt to different and changing environmental conditions. Nevertheless, all this variety is the manifestation of the three strategic line of the adaptation process: 1. Evolutional or genotypic adaptation. 2. Phenotypic adaptation. 3. Rapid adaptation.

Physical Principles of Biomembranes and Cells

Physical Principles of Biomembranes and Cells PDF

Author: Kazuo Ohki

Publisher: Springer

Published: 2018-10-10

Total Pages: 170

ISBN-13: 4431568417

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This book describes how biologically available free energy sources (ATP, chemical potential, and membrane potentials, among others) can be used to drive synthetic reactions, signaling in cells, and various types of motion such as membrane traffic, active transport, and cell locomotion. As such, it approaches the concept of the energy cycle of life on Earth from a physical point of view, covering topics ranging from an introduction to chemical evolution, to an examination of the catalytic activity of enzymes associated with the genome in Darwinian evolution. The author introduces the relationship between functions and physical properties in biomembranes, explaining the methods and equipment used in biophysics research to help researchers unravel the still-unsolved mysteries of life. The physical principles needed to understand the cellular functions are provided; these functions are associated with biomembranes and regulated by physical properties of the lipid bilayer such as membrane fluidity, phase transition, and phase separation, as shown in lipid rafts. Other key dynamic aspects of life (cell locomotion, cytoskeletal dynamics, and sensitivities of the cell to physical stimuli such as external forces and temperature) are also discussed. Lastly, readers will learn how life on Earth and its ecological system are maintained by solar energy, and be provided further information on the problems accompanying global warming.

New Techniques for Studying Biomembranes

New Techniques for Studying Biomembranes PDF

Author: Taylor & Francis Group

Publisher: CRC Press

Published: 2021-12-13

Total Pages: 180

ISBN-13: 9781032242378

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This book describes methods used to investigate the function and distribution of lipids in membranes. Contributors present discoveries that have to do with lipid analysis and lipid interactions with other components of membranes, such as proteins, receptors, transporters and ion channels.

Physics of Biological Membranes

Physics of Biological Membranes PDF

Author: Patricia Bassereau

Publisher: Springer

Published: 2018-12-30

Total Pages: 623

ISBN-13: 3030006301

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This book mainly focuses on key aspects of biomembranes that have emerged over the past 15 years. It covers static and dynamic descriptions, as well as modeling for membrane organization and shape at the local and global (at the cell level) scale. It also discusses several new developments in non-equilibrium aspects that have not yet been covered elsewhere. Biological membranes are the seat of interactions between cells and the rest of the world, and internally, they are at the core of complex dynamic reorganizations and chemical reactions. Despite the long tradition of membrane research in biophysics, the physics of cell membranes as well as of biomimetic or synthetic membranes is a rapidly developing field. Though successful books have already been published on this topic over the past decades, none include the most recent advances. Additionally, in this domain, the traditional distinction between biological and physical approaches tends to blur. This book gathers the most recent advances in this area, and will benefit biologists and physicists alike.

Mechanics and Thermodynamics of Biomembranes

Mechanics and Thermodynamics of Biomembranes PDF

Author: Eustace Anthony Evans

Publisher: CRC Press

Published: 2018-01-18

Total Pages: 262

ISBN-13: 1351082787

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This tutorial provides an introduction to the determination of mechanical properties of biological membranes and methods of analysis useful in their interpretation. These methods are based on fundamentals of continuum mechanics, thermodynamics, and mechanics of thin shells. This article is intended primarily for engineering and physical scientists who are interested in the physical behaviour and structure of biological membranes.

Biomembrane Simulations

Biomembrane Simulations PDF

Author: Max L. Berkowitz

Publisher: CRC Press

Published: 2019-04-30

Total Pages: 258

ISBN-13: 1351060309

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Due to recent advancements in the development of numerical algorithms and computational hardware, computer simulations of biological membranes, often requiring use of substantial computational resources, are now reaching a mature stage. Since molecular processes in membranes occur on a multitude of spatial and time scales, molecular simulations of membranes can also serve as a testing ground for use of multi-scale simulation techniques. This book addresses some of the important issues related to understanding properties and behavior of model biological membranes and it Shows how simulations improve our understanding of biological membranes and makes connections with experimental results. Presents a careful discussion of the force fields used in the membrane simulations including detailed all-atom fields and coarse-grained fields. Presents a continuum description of membranes. Discusses a variety of issues such as influence of membrane surfaces on properties of water, interaction between membranes across water, nanoparticle permeation across the membrane, action of anesthetics and creation of inhomogeneous regions in membranes. Discusses important methodological issues when using simulations to examine phenomena such as pore creation and permeation across membranes. Discusses progress recently achieved in modeling bacterial membranes. It will be a valuable resource for graduate students, researchers and instructors in biochemistry, biophysics, pharmacology, physiology, and computational biology.

Electromagnetic Fields and Biomembranes

Electromagnetic Fields and Biomembranes PDF

Author: M. Markov

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 301

ISBN-13: 146159507X

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The First International School on "Electromagnetic Fields and Biomembranes" took place in Pleven, Bulgaria on 6-12 October 1986. It was designed as an advanced course through a collaboration of the Biological Faculty of Sofia University and the Council of the Bioelectrochemical Society. In an advanced course the lecturers are specialized in particular areas, and the students are usually specialists in related areas. We have captured the expertise of both groups of participants in this volume. The longer papers prepared by the lecturers are joined with the shorter papers based on the posters presented by the "students" to provide a summary of the school as well as an indication of current research directions in the field. The course was designed to provide the latest information about biomembrane structure and function, covering the properties of both the lipid matrix and the recently characterized proteins that function as specialized channels and receptors. Real membranes and various models were covered, with an emphasis on understanding their mechanisms of interaction with various exogenous stimuli (e.g., electric, magnetic, light, etc.). Several practical applications of this information (e.g., electroporation, electro-fusion) were also presented with indications of the possibilities for new developments in biotechnology. The mixture of basic science with practical applications, together with the int~rmingling of lecturers and students from many different countries produced a stimulating atmosphere and effective teaching. We hope that this volume will transmit some of this atmosphere.

Structure and Dynamics of Membranes

Structure and Dynamics of Membranes PDF

Author: R. Lipowsky

Publisher: Elsevier

Published: 1995-06-15

Total Pages: 537

ISBN-13: 0080541917

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The first volume of the Handbook deals with the amazing world of biomembranes and lipid bilayers. Part A describes all aspects related to the morphology of these membranes, beginning with the complex architecture of biomembranes, continues with a description of the bizarre morphology of lipid bilayers and concludes with technological applications of these membranes. The first two chapters deal with biomembranes, providing an introduction to the membranes of eucaryotes and a description of the evolution of membranes. The following chapters are concerned with different aspects of lipids including the physical properties of model membranes composed of lipid-protein mixtures, lateralphase separation of lipids and proteins and measurement of lipid-protein bilayer diffusion. Other chapters deal with the flexibility of fluid bilayers, the closure of bilayers into vesicles which attain a large variety of different shapes, and applications of lipid vesicles and liposomes. Part B covers membrane adhesion, membrane fusion and the interaction of biomembranes withpolymer networks such as the cytoskeleton. The first two chapters of this part discuss the generic interactions of membranes from the conceptual point of view. The following two chapters summarize the experimental work on two different bilayer systems. The next chapter deals with the process ofcontact formation, focal bounding and macroscopic contacts between cells. The cytoskeleton within eucaryotic cells consists of a network of relatively stiff filaments of which three different types of filaments have been identified. As explained in the next chapter much has been recently learned aboutthe interaction of these filaments with the cell membrane. The final two chapters deal with membrane fusion.